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Appointed: 2008

John Mosher, Ph.D.

(216) 444-3379

John Mosher, Ph.D.

Department: Epilepsy Center
Location: Cleveland Clinic Main Campus
Mail Code S51
9500 Euclid Avenue
Cleveland, OH 44195
WorkPhone:(216) 444-3379

Biographical Sketch

John C. Mosher, PhD, received his Bachelors in Electrical Engineering with Highest Honors from the Georgia Institute of Technology in 1983. From 1981 - 1982 he was an exchange scholar student with the Eidgen'ssische Technische Hochschule Zuerich, Switzerland. From 1979 - 1983 he was also a Cooperative Education student with Hughes Aircraft Company in Fullerton, California. From 1983 - 1993, he worked at TRW in Los Angeles, California, as a scientist and senior scientist researching signal analysis procedures for electromagnetic pulse effects on aircraft. While at TRW, he received his M.S. (1985) and Ph.D. (1993) in Electrical Engineering from the Signal & Image Processing Institute of the University of Southern California. Upon graduation in 1993, he accepted a staff position at the Los Alamos National Laboratory, Los Alamos, New Mexico. In May 2008, Dr. Mosher joined the Physician Staff in the Epilepsy Center to head its new magnetoencephalography (MEG) research program.

Since 1994, Dr. Mosher has been without interruption a Principal Investigator or Co-Investigator on competitive grants from the National Institutes of Health, as well as several competitive Laboratory Directed Research and Development grants. In his research role, he has served as a formal Mentor of Laboratory-employed students and post-docs, and as an informal mentor of his collaborator?s students and post-docs. Working closely with these students and his collaborators, he has continuously published in his field of biomedical research since 1990.

As of October 2007, Dr. Mosher has over 1,400 citations to over 100 papers appearing in the ISI Citation database, with over 160 of these citations since 2006. His landmark paper in 1992 remains today one of the most cited original research papers in magnetoencephalography, with over 400 total citations of the original article, with over 50 citations since 2006 alone. Additionally, this 1992 paper was included in the landmark 1993 review paper, "Magnetoencephalography" theory, instrumentation, and applications to noninvasive studies of the working human brain,  M Hamalainen, R Hari, RJ Ilmoniemi, J Knuutila, Reviews of Modern Physics, which itself now has nearly 1,100 citations (nearly 200 citations since 2006), making Dr. Mosher's notation and approach one of the standard's in MEG signal processing.

Education & Fellowships

Doctorate - University of Southern California
electrical engineering
Los Angeles, CA USA
1993
Undergraduate - Georgia Institute of Technology
electrical engineering
Atlanta, GA USA
1983

Specialty Interests

Epilepsy electroencephalography (EEG) and magnetoencephalography (MEG) recording and analysis for detection of abnormal activity, localization of possible seizure onset zones, imaging of analysis, registration with MRI, fMRI, PET, and SPECT images

Treatment & Services

  • Clinical Trials
  • Dipole Modeling
  • Inverse Imaging
  • Inverse Modeling
  • Magnetoencephalography (meg)
  • Principal Components Analysis
  • Signal Subspace Filtering

Specialty in Diseases and Conditions

Industry Relationships

Cleveland Clinic physicians and scientists report if they have any collaborations with the pharmaceutical or medical device industries as part of the Cleveland Clinic’s procedures. The Cleveland Clinic publicly discloses payments to its physicians and scientists for speaking and consulting of $5,000 or more per year, and any equity, royalties, and fiduciary relationships in companies with which they collaborate. In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its doctors’ connections with industry and those of their immediate family members. As of 7/31/2008, Dr. Mosher has reported no financial relationship with industry that is applicable to this listing. Patients should feel free to contact their doctor about relationships with industry and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic’s policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Languages Spoken

  • English