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Appointed: 1989

Allan Klein, M.D.

(216) 444-3932

Allan Klein, M.D.

Department: Cardiovascular Medicine
Location: Cleveland Clinic Main Campus
Mail Code J1-5
9500 Euclid Avenue
Cleveland, OH 44195
WorkPhone:(216) 444-3932

Biographical Sketch

Allan Klein, MD, is the Director of Cardiovascular Imaging Research and a staff cardiologist in the Section of Cardiovascular Imaging, the Robert and Suzanne Tomsich Department of Cardiovascular Medicine, at the Sydell and Arnold Miller Family Heart & Vascular Institute, where he is also the Course Director for Diastology and Contrast Echo & New Technologies Courses. He is board-certified in internal medicine and cardiology. His specialty interests include cardiac imaging, echocardiography, valvular heart disease, atrial fibrillation, pericardial diseases and diastolic heart failure.

A Canadian by birth, Dr. Klein speaks fluent French and English. He received his medical degree from McGill University in Montreal, Quebec after completing an undergraduate degree in microbiology and immunology, graduating with honors. While in medical school, he received several scholarships and graduated in the top 10 percent of his class. Dr. Klein completed his clinical training at Mount Sinai Hospital in Toronto and the Royal Victoria Hospital in Montreal. He completed a Cardiology Residency from the University of Ottawa Heart Institute and a Research Fellowship from the Mayo Clinic in Rochester, Minn. He was appointed to Cleveland Clinic in 1989.

In addition to his scholarships and academic achievements, Dr. Klein won the E.G.D. Murray Prize in Microbiology and Immunology and was named as mentor for the nominees of the American Society of Echocardiography Research Finalist Award and for the ASE Fellowship Award.

Dr. Klein has been course director and workshop leader at numerous medical specialty conferences focused on clinical trials, imaging modalities and clinical protocols, to name a few. He currently serves as Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. He is a member of the Admissions committee at the Lerner College of Medicine and teaches the students physical diagnosis of cardiology.

He is principal or co-principal investigator on a number of current research studies related to atrial fibrillation, heart failure and cardiac imaging. His most recent research project was the principal investigator on the ACUTE II Multicenter Study. He has published key articles in such prestigious journals such as New England Journal of Medicine, Lancet and European Heart Journal.

Dr. Klein has served on the Board of Directors of the American Society of Echocardiography. He serves as a peer reviewer for more than 15 professional journals. He also grades abstracts for the American College of Cardiology, the American Society of Echocardiography and the American Heart Association.

He has been an invited lecturer at many national and international symposia and conferences, speaking on topics related to his specialty interests. He has authored or co-authored more than 166 peer-reviewed articles in professional journals, written 12 chapters in medical textbooks and published more than 300 abstracts. He is also an Editor of a book entitled "Diastology: Clinical Approach to Diastolic Heart Failure."

Dr. Klein is a Fellow in the Council on Clinical Cardiology, the American College of Cardiology, and the Royal College of Physicians. In addition, he is a member of the, the American Society of Echocardiography, the American Medical Association and the American Heart Association.

A long-time hockey player, Dr. Klein currently plays in the Auburn Hockey League. He also plays piano.

Professional Highlights

  • 2007:  Grand Rounds presentation at Massachusetts General Hospital on "New Advances in Echocardiography in Atrial Fibrillation:  What's New in the LAA and Pulmonary Veins?"
  • 2006:  Publication of “The use of enoxaparin compared with unfractionated heparin for short-term antithrombotic therapy in atrial fibrillation patients undergoing transesophageal echocardiography-guided cardioversion:  Assessment of Cardioversion Using Transesophageal Echocardiography (ACUTE) II randomized multicentre study” in the European Heart Journal
  • 2006:  Key note speaker on "New Advances in Echocardiography in Atrial Fibrillation" in Rome at the X World Congress of Echocardiography & Cardiovascular Imaging Conference
  • 2004:  Publication of “Pericarditis” in The Lancet
  • 2001:  Publication of “Use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation” in the New England Journal of Medicine

Education & Fellowships

Fellowship - Mayo Clinic
Cardiovascular Diseases
Rochester, MN USA
1988
Residency - University of Ottawa Heart Institute
Cardiology
Ottawa, Ontario Canada
1986
Residency - Royal Victoria Hospital
Internal Medicine
Montreal, Quebec Canada
1984
Internship - Mount Sinai Hospital
Internal Medicine
Toronto, Ontario Canada
1982
Medical School - McGill University Faculty of Medicine
Montreal, Quebec Canada
1981
Undergraduate - McGill University
Montreal, Quebec Canada
1977

Certifications

  • Internal Medicine
  • Internal Medicine- Cardiovascular Disease

Specialty Interests

intraoperative transesophageal echocardiography, clinical cardiology, diastolic function, pericardial diseases and infiltrative cardiomyopathy, valvular heart disease, atrial fibrillation, contrast echocardiography

Awards & Honors

  • Fellowships: American College of Cardiology, Royal College of Physicians (Canada), American Society of Echocardiography, American Heart Association
  • Principal Investigator for harmonic imaging of the left atrial appendage with atrial  fibrillation study (CLOTS)
  • Principal Investigator for the ACUTE II Low Molecular Weight Heparin study
  • Principal Investigator for A Pilot Phase 3, International, Multicenter, Open-label, Dual Injection,
  • Myocardial Imaging and Safety Study of AI-700 in patients with Suspected Ischemic Heart Disease
  • Principal Investigator for the American Society of Echo. Research Award for “Predication of Responses to Beta-Blocker Therapy in Heart Failure Using Doppler Filling Patterns of the Left Ventricle”
  • Principal Investigator for the American Society of Echo. Outcomes Award. The Role of Transesophageal Echocardiography in Pulmonary Vein Ablation: Comparison with Computed Tomography: The ROTEA Study
  • Principal Investigator.  Low Molecular Weight Heparin in Bridging Patients after Mechanical Valve Replacement. (ABRIDGE MVR Study)

Additional Training

  • Participant in the Cleveland Clinic's Cardiovascular CT Training Program in March, 2006 (Level II certification)
  • Participant at the 5th Annual Cardiovascular Magnetic Resonance & Computed Tomography Conference, June,2007. Effective January 2, 2008, met the Level 2 requirements for training in Cardiac CT (CCT) based on the ACCF/AHA Clinical Competency Statement on Cardiac Imaging with Computed Tomography and Magnetic Resonance

Innovations & Patents

Dr. Klein has pioneered the use of transesophageal-guided cardioversion in patients with atrial fibrillation in his landmark paper in the New England Journal of Medicine published in 2001 and the European Heart Journal in 2006. 

He is also the Director of the echocardiographic symposiums entitled Diastology and New Echo Technologies and is the editor of a book entitled "Diastology:  Clinical Approach to Diastolic Heart Failure."

Memberships

  • American Society of Echocardiography
  • American Heart Association
  • American College of Cardiology
  • Royal College of Physicians
  • Society of Cardiovascular Computed Tomography

Treatment & Services

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical education about recent trends. The collaborations are reviewed as part of the Cleveland Clinic’s procedures. The Cleveland Clinic publicly discloses payments to its physicians and scientists for speaking and consulting of $5,000 or more per year, and any equity, royalties, and fiduciary relationships in companies with which they collaborate. In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its doctors’ connections with industry and those of their immediate family members. As of 9/4/2008, Dr. Klein has reported the financial relationships with the companies listed below. Patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic’s policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting. Dr. Klein receives fees of $5,000 or more per year as a paid consultant or speaker for the following companies:

Beacon Bioscience Inc.

ICON

Medicus NY (Sanofi)

Languages Spoken

  • English
  • French