Jonathan Scharfstein, MD


4.8 out of 5
281 Patient Satisfaction Ratings 13 Comments
Jonathan Scharfstein, MD
Department: Cardiovascular Medicine
Location: Hillcrest Medical Building 2
Mail Code Suite 300
6801 Mayfield Road
Mayfield Heights, OH 44124
Type of Doctor:
Adults Only

Biographical Sketch

Jonathan S. Scharfstein, MD, FACC, is a staff physician in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Sydell and Arnold Miller Family Heart & Vascular Institute and practices at Hillcrest Hospital with office in the Hillcrest Medical Building. Dr. Scharfstein is Chief of the Division of Cardiology, Medical Director of the Coronary Care Unit and has been the Medical Director of the Chest Pain Center since 2007 at Hillcrest Hospital. He is board -certified in internal medicine, cardiovascular disease and interventional cardiology.

Prior to his appointment to the Cleveland Clinic staff, Dr. Scharfstein was in private practice with Cardiovascular Associates of Cleveland. He has been on the medical staff at Hillcrest since 2000. His previous positions include appointments at Brigham and Women’s and University Hospitals in Boston, MA, Director of Interventional Cardiology and the cardiology fellowship training program at The Mt. Sinai Medical Center, Cleveland, and Co-Director of the cardiology fellowship training program at University Hospitals of Cleveland.

Specialty Interests: Coronary artery disease, angina, heart valve disease, hyperlipidemia, chest pain, heart catheterization, coronary angioplasty, coronary stenting

Number of Procedures Performed: Dr. Scharfstein has performed more than 6,000 heart catheterizations and 2,000 coronary interventions throughout his career.

Success Rates: Cleveland Clinic has been ranked the #1 hospital for cardiology and heart surgery by U.S. News & World Report since 1994. Success rates for specific procedures are available at:

Education and Training: Dr. Scharfstein earned his undergraduate degree from Princeton University and his medical degree from the University of Pennsylvania School of Medicine. He served an internship and residency in medicine at The Johns Hopkins Hospital, Baltimore, MD. He completed fellowships in clinical cardiology and interventional cardiology at Brigham and Women’s Hospital, Boston, MA, a research fellowship in medicine at Harvard University, Cambridge, MA, and a second fellowship in interventional cardiology at University Hospital, Boston.

In addition to his research fellowship at Harvard, which included teaching responsibilities, Dr. Scharfstein’s academic appointments have included clinical instructor positions at Harvard Medical School and Boston University School of Medicine. He has been an Assistant Professor of Medicine at Case Western Reserve University School of Medicine in Cleveland since 1995.

Research, Publications and Speaking: Dr. Scharfstein has been an investigator on a number of significant clinical trials related to interventional strategies for heart attack, and has published more than a dozen original papers, reviews and abstracts in professional journals.

About Dr. Scharfstein: “I enjoy cardiology because of the diversity of diseases in the field, all with their unique acute and chronic challenges.  I also enjoy meeting patients for the first time in the midst of an acute illness, such as a heart attack, providing them emergency care, getting them through their initial crisis, and then providing follow-up care over long periods of time.”

Leisure time activities: In his leisure time, Dr. Scharfstein enjoys golfing, travel, exercise and spending time with his family

Education & Fellowships

Fellowship - Boston Medical Center
Interventional Cardiology
Boston, MA USA
Fellowship - Brigham & Women's Hospital
Cardiovascular Disease
Boston, MA
Residency - Johns Hopkins Hospital
Internal Medicine
Baltimore, MD USA
Medical School - University of Pennsylvania School of Medicine
Philadelphia, PA USA
Undergraduate - Princeton University
Princeton, NJ USA


  • Internal Medicine
  • Internal Medicine- Cardiovascular Disease
  • Internal Medicine- Interventional Cardiology

Specialty Interests

Coronary artery disease, angina, heart valve disease, hyperlipidemia, chest pain, heart catheterization, coronary angioplasty, coronary stenting

Awards & Honors

2009 – present, Best Doctors in America


  • Fellow, American College of Cardiology
  • American Heart Association

Treatment & Services

  • Abnormal Stress Test
  • Cardiac Catheterization
  • Cardiovascular Medicine Department
  • Catheterization (and Pre-Cath Exam)
  • Coronary Artery Atherectomy
  • Coronary Artery Stenting
  • Coronary Balloon Angioplasty (PTCA)
  • Electrocardiograph Tests
  • General Cardiology
  • Preventive Cardiology
  • Regional Heart and Vascular
  • Stress Testing

Specialty in Diseases and Conditions

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. The Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 5/5/2015, Dr. Scharfstein has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English

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