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Gynecologic Infectious Disease Program

Our center focuses on diagnosing and treating infections that impact a woman’s gynecologic and reproductive health. The infections may be those of the female reproductive tract and female genitalia, infections during pregnancy, pelvic infections, post-operative infections, and sexually transmitted infections.

In addition, we evaluate and manage non-infectious disorders of the vulva as well as vulvar diseases and/or care for women with recurrent or resistant vulvar or vaginal infections.

About Dr. Goje (Jaiyeoba)

Oluwatosin Goje (Jaiyeoba), who leads the Reproductive Infectious Diseases Program at Cleveland Clinic, is an Obstetrician Gynecologist fellowship-trained in Infectious Diseases at the Medical University of South Carolina, Charleston, SC, one of four academic centers that offer this specialty training in North America.

Auto-Immune Disorders (like Bechet’s)

In auto-immune disorders, the body’s immune system is triggered to attack healthy cells and tissues.

Bartholin’s Cyst

When a Bartholin’s gland becomes blocked and the gland becomes inflamed a cyst may result.

Condyloma Accuminata (Genital Warts)

Genital warts are growths or bumps on the penis, vagina, vulva (vaginal lips), cervix (the opening between the vagina and the womb), rectum, or groin. The warts are caused by a number of different viruses. These viruses are among a group of more than 60 viruses that are called HPV.

Contact or Irritant Dermatitis of the Vulva

Skin condition characterized by exposure to allergens or irritants that produce vulvar or vaginal itching and burning.

Desquamative Inflammatory Vaginitis

With this condition, the lining of the vagina becomes inflamed and is often characterized by greenish-yellow vaginal discharge, vulvar irritation and pain during intercourse.

Hepatitis A

Hepatitis is a disease that damages the liver. Viruses cause most cases of hepatitis, but alcohol, drugs, and other factors can also cause the disease.

Hepatitis B

Hepatitis B is a serious form of hepatitis caused by a virus. It affects people of all ages around the world. The hepatitis B virus attacks the liver. The virus can lead to serious illness, liver damage and, in some cases, death.

Hepatitis C

Hepatitis C is a virus that infects the liver. It is mainly transmitted by parenteral means (by way of infected needles or blood, not by contaminated food).

Herpes Simplex Virus (HSV)

There are two subtypes of herpes simplex viruses. The first type is herpes simplex type 1 (or HSV-1). HSV-1 occurs most often on or near the mouth and appears as a chancre or cold sore. The second type, herpes simplex type 2 (or HSV-2), occurs most often on or near the sex organs and is sometimes called “genital herpes.” Herpes virus is spread by close personal contact, such as kissing or sexual intercourse. Genital herpes is a sexually transmitted infection, or “STI.”

Hidradenitis Suppurativa

A chronic disease characterized by clusters of abscesses or nodules that form under the skin.

Human Immunodeficiency Virus

Human immunodeficiency virus (HIV) is the virus, that causes acquired immune deficiency syndrome (AIDS). The virus weakens a person's ability to fight infections and cancer. People with HIV are said to have AIDS when the virus makes them very sick and they develop certain infections or cancers.

With advances in technology and new drugs, our team is able to manage these patients so that they can have a productive life.

Pelvic Inflammatory Disease

Pelvic inflammatory disease (PID) is an inflammatory condition of the female reproductive organs cause by polymicrobial ascending infection. PID can damage the uterus, ovaries, fallopian tubes or other parts of the female reproductive system. It also can cause severe pain and make it difficult to become pregnant.

Post Herpetic Pain/Neuralgia

Nerve pain due to damage caused by the varicella zoster virus.

Recurrent Bacterial Vaginosis

An imbalance of bacteria normally found in the vagina.

Recurrent Vaginal Yeast Infections

If the population of yeast in the vagina increases greatly, a yeast infection is said to occur.

Sexually Transmitted Infections (STI)

Sexually transmitted infections, commonly called STIs, are diseases that are spread by having sex with someone who has an STI.


Syphilis is an infection caused by the bacteria Treponema pallidum. It is a sexually transmitted infection (STI), which means that it is spread by having sex with an infected person.

Tubal Ovarian Abscesses

Tubal Ovarian Abscesses are a complication or severe form of PID, and could be life threatening if not managed appropriately.


"Vaginitis" is a medical term used to describe various disorders that cause infection or inflammation of the vagina. The symptoms of vaginitis can vary depending on what is causing the infection or inflammation. Some women have no symptoms at all.

Vaginitis could be infectious in origin when it is caused by candida, bacterial vaginosis ( BV) or trichomonas vaginalis. It could also be allergic or contact dermatitis or inflammatory vaginitis.

Other conditions of the vagina include atrophic vaginitis, desquamative inflammatory vaginitis, Lichen planus and Lichen sclerosis.

Vulvar Abscess

An infection that develops in vulvar skin or subcutaneous tissues.

Vulvar Lichen Planus

An inflammatory disease that can cause an itchy or burning rash or painful purple lesions, occurring on the skin of the arms or legs, or affecting the vulva and vagina.

Vulvar Lichen Sclerosus

Chronic skin disease that mainly affects the vulva, but it can also involve skin outside the genital region.

Vulvodynia and Vulvar Vestibulitis

Condition characterized by chronic discomfort inside the vulva, the entrance to the vagina and the urethra.

Yeast Infections

A yeast infection is caused by fungi that normally grow in the body. (Yeast is a kind of fungus). A change in the chemical balance in the vagina allows the fungus to grow too rapidly and cause symptoms. Yeast infections most often occur in a woman's vagina.

Vulvar and Vaginal Disorders Clinic (VVDC)

Cleveland Clinic's Ob/Gyn and Women's Health Institute VVDC specializes in the diagnosis and treatment of women with chronic vulvo-vaginal disorders. Vulvo-vaginal disorders could be infectious or non- infectious in etiology. Women who suffer from vulvar or vaginal health conditions may experience any of the following symptoms:

  • Abnormal, or heavy vaginal discharge that is gray, yellow, or milky in color
  • Abnormal vaginal odor
  • Vulvar irritation
  • Vulvar lesions, boils or sores
  • Painful intercourse
  • Itching or burning in the genital area
  • Unusual pain and redness in the genital area
  • Fragile skin in the genital area
  • Hypopigmentation or depigmentation of the skin of the area

Infectious Diseases in Pregnancy

The team using a multi-disciplinary approach manages HIV in pregnancy, syphilis in pregnancy, hepatitis B, hepatitis C, HSV in pregnancy to mention just a few.

In collaboration with Cleveland Clinic's Infectious Disease department, we offer preconception counseling to HIV positive men and women. We provide pre-conception counseling for sero-discordant or sero-concordant HIV couples and offer Pre-exposure prophylaxis ( PreP) counseling, as well.

Sexually Transmitted Diseases (STD) Treatment
  • HIV
  • Syphilis
  • Hepatitis
  • HSV
  • Trichomoniasis
  • HSV
  • Genital warts
  • Gonorrhea
  • Chlamydia

Cleveland Clinic Main Campus

Department of Obstetrics & Gynecology, Desk A81
2049 East 100th St.
Cleveland, Ohio 44195
Phone: 216.444.6601
Toll-free: 800.CCF.CARE, extension 46601

Hillcrest Hospital Medical Building Atrium

6770 Mayfield Rd. #426
Mayfield Heights, Ohio 44124
Phone: 440.312.2229

Vulvar Self-Exam

Self-examination of the vulvar is good practice. Vulvar examination will help you be aware of any changes in the vulva, if any problem occurs, you catch it early and we are able to institute treatment early.

Always wash your hands before starting a self-exam, lie or sit up in a comfortable position with good lighting and a mirror. You may need to prop up on pillows or squat or kneel depending on the position which is more comfortable for you.

Start from the Mons pubis just beneath the lower abdomen and groin area. Continue with the outer lips of vulvar. Be sure you separate the outer lips and look for redness, swelling, dark spots or light spots, blisters or bumps. Check the inner lips for the same. Remember to pool by the skin of the clitoris and check the clitoral hood, followed by urethra, perineum and anal area also. Look for look for redness, swelling, dark spots or light spots, blisters or bumps.

Some Suggested Vulvar Pain & Itching Measure

The vulva is the external genitalia in the female. It is sensitive and can be irritated by moisture, sitting and standing, or by movement. Always endeavor to keep the area dry; it helps with healing. Chemicals found in toilet tissue, bathing soaps and laundry detergent may sometimes irritate women who have sensitive skin. Chemicals in fabric softener used in under garments, feminine products, deodorant soap, bubble baths and panty liners may sometimes irritate the vulva.

If you get irritated easily, we suggest:

  • Wear white 100% cotton underwear
  • Do not wear underwear at bedtime
  • Avoid panty hose, tights and tight fitting clothes
  • Avoid fabric softener or dryer sheets on your undergarments and give undergarments extra rinsing to make sure all detergent residues are gone
  • Rinse with water after using the bathroom
  • Watch out for irritants, e.g., condoms or spermicidal creams

Important Things to Remember About Vulvar Pain

  • Vulvar pain can be difficult to treat. Treatment may take months. Some women may have spontaneous remission of symptoms, while others may need multiple attempts with medical management.
  • Vulvar pain is not generally associated with malignancy.
  • The pain is usually not associated with sexually transmitted disease and is not contagious to your partner.
  • Vulvar pain is usually not due to poor hygiene. Use gentle soap or no soap, allowing water alone to cleanse the perineum.
  • Treatment setbacks can occur; they are not the faults of your heath car provider or you. We understand that chronic pain is exhausting and may be demoralizing.
  • It is not about you, there is nothing wrong with you as a person. The problem is your pain.
  • It is good to seek knowledge and second opinion and to get involved.

Research activity in the areas that comprise gynecologic infectious disease is multi-disciplinary and on-going. For information about women’s infectious disease and pelvic health issues: