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Diana L. Karius

Diana L. Karius


Clinical Nurse Specialist, Oncology and Palliative Medicine,
Cleveland Clinic Main Campus

Executive Summary

Diana L. Karius, MSN, RN, AOCN, is a clinical nurse specialist for the oncology and palliative medicine units at Cleveland Clinic main campus. With more than a decade of experience in her current role, Karius is a trusted leader among the caregiver team. She is responsible for education, monitoring and enhancing practice for inpatient oncology and palliative medicine nursing units. She also supports the outpatient oncology and gynecological oncology treatment clinics. Karius serves as a primary chemotherapy resource for the health system.

Karius entered the profession of nursing in 1979, and her extensive career includes healthcare organizations such as the College of Nursing at Valparaiso University, the University of Chicago Medical Center, University Hospital Home Care in Cleveland, and the Cleveland Clinic Taussig Cancer Institute. Throughout her career she has worked as a clinical teaching assistant, research clinical specialist, case manager and oncology clinical nurse specialist. With research and evidence-based practice at the forefront of her patient care philosophy, Karius is a member of several national and local industry associations, has served as a publication content reviewer, and is a well-versed presenter. She has also taught as an adjunct faculty member at three Northeast Ohio schools of nursing.


  • MS, Purdue University, Purdue, Indiana, 1993
  • BSN, Kent State University, Kent, Ohio, 1979


  • Certified Advanced Oncology Nurse (AOCN), Oncology Nursing Certification Corporation
  • Certified Hospice and Palliative Care Nurse (CHPN), National Board for Certification of Hospice and Palliative Nurses


A tenured clinical nurse leader within the units she serves, since 2000, Karius has implemented processes, educational initiatives and more to aid her colleagues in delivering superior patient care. Throughout her career she has been looked at as a clinical resource for physicians and staff members. She has mentored Master’s-prepared clinical nurse specialist students, consulted on nutrition in oncology patients, and acted as a preceptor for oncology and neuro-oncology fellows.

Clinical Practice

Karius’ clinical expertise lies within the area of oncology nursing, chemotherapy, biotherapy and the management of solid tumor patient populations. She has additional experience in palliative care nursing, pain and symptom management as well end-of-life care.


An experienced educator, Karius has served as an external consultant to the Abbott Advisory Board on nutrition in oncology patients for the Oncology Nursing Society’s Congress, and also co-authored a web-based course for the organization. She has precepted for oncology and neuro-oncology fellows in ommaya access and treatment, and has also taught as an adjunct faculty member at the following institutions:

  • Case Western Reserve University, Frances Payne Bolton School of Nursing, Cleveland, Ohio
  • University of Akron College of Nursing, Akron, Ohio
  • Kent State University College of Nursing, Kent, Ohio

Research, Publications & Presentations

With a career history that encompasses many notable publications and presentations, Karius has produced works on topics ranging from intraperitoneal chemotherapy and standardization of chemotherapy administration to improving patient safety on an inpatient palliative medicine unit and more. She served as an article and book reviewer for American Nurse Today and Clinical Nurse Specialist and has conducted research on the comfort and capability of nurses taking care of patients at end of life, and more.

View a selection of her work.


2009. Co-Investigator. Comfort and capability of nurses taking care of patients at end of life.

2003. Principle Investigator. Chloraprep incident study.


Powaski R, Walsh D, Cothren B, Rybicki L, Thomas S, Morgan G, Karius D, Davis M, Shrotriya S. The care of the actively dying in an academic medical center: a survey of registered nurses. American Journal of Hospice and Palliative Medicine. October 16, 2013.

Karius D. Intraperitoneal chemotherapy, Nursing Considerations. American Nurse Today. May 2010.

Karius D, and Marriott P. Immunologic advances in monoclonal antibody therapy: Implications for oncology nursing. Oncology Nursing Forum. April 1997

Karius D, and O’Brien S. Oncology nursing practice in the care of G.U. patients. Comprehensive Textbook of Genitourinary Oncology. Wilkens & Wilkens, 1995. Revised for re-release 2000 under Karius D, O’Brien S, Dumas M.

Stadler WM, Karius D, Rybak ME, Vogelzang NJ. Recombinant Human IL-4 in renal cell carcinoma: Evidence of biologic activity without clinical response. ASCO. 1994. [abstract]

Lestingi TM, Richards JM, Shulman K, Gale D, Karius D, Issacs R, Levitt D. Pilot Phase II Study of recombinant human interlukin-6 and chemotherapy in metastatic melanoma. ASCO. 1994 [abstract].


“Pain Control: Interdisciplinary Process for Improving Pain Management at an Oncology Unit in a Multi-specialty Teaching Institution,” at the ONS Congress; Washington D.C. April 2013. [poster presentation]

“Oncology Education and Practice Council, a model for standardization and collaboration,” at the ICCN Conference; Atlanta, Georgia; March 2010.

“Speaking the Same Language: Nurse, Physician Communication,” Co-presented with Dr. Susan LeGrand at the Annual Hospice and Palliative Medicine Conference; Scottsdale, Arizona; March 2008.

“Improving Patient Safety on an In-patient Palliative Medicine Unit,” at the Annual Hospice and Palliative Medicine Conference; Scottsdale, Arizona; March 2008. [poster presentation]

“ELNEC training for Oncology Nurses,” at the ONS Congress; Boston, Massachusetts; May 2006. [abstract & poster presentation]

ONS Chemotherapy and Biotherapy Course IOL; Pittsburgh, Pennsylvania; November 2006. “Improving Patient Safety: Implementation of a Falls Assessment Tool and Interventions Specific to Hospitalized Oncology Patients,” at the ONS Congress; San Antonio, Texas; 2009. [poster presentation]

“Control of CINV: Sparking a Change in your Practice,” an ONS National Web-cast, September 2005; Presented in Modesto, California 2007; Oakland, California 2008; Toledo, Ohio 2009; Columbus, Ohio 2009.

Hematology and Immunology Progressive Care Certified Nurse Review Course, November 2005 Critical Care Review Course, 2007, 2008 Certified Rehabilitation Nurse Review 2009, 2010; Cleveland, Ohio.

“Symptom Management Oncology Basic Seminar,” at Cleveland State University; Cleveland, Ohio; June 2005.

Oncology Certification Review Course; Cleveland, Ohio; 2004 – 2013.

“Improving Chemotherapy Safety in a Multi-specialty Tertiary Referral,” at the ONS Congress; Denver, Colorado; May 2003. [podium presentation]

“Ethics and Prejudice in patient care. A study in Lung cancer,” at the Medical Service Corporation; Independence, Ohio; September 2002, October 2003.

Professional Involvement

  • Member, Northeast Ohio Association of Vascular Access
  • Member, Oncology Nursing Society
  • Member, Cleveland Chapter Oncology Nursing Society, Past Co-Chair, Program Committee
  • Past Member, Chicago Chapter Oncology Nursing Society
  • Trainer, Critical Care End-of-Life Nursing Education Consortium (ELNEC) and ELNEC Core
  • Trainer, Oncology Genetics
  • Ommaya Access, National Institutes of Health
  • Previous Course Trainer, Oncology Nursing Society Chemotherapy and Biotherapy
  • Member, Oncology Nursing Society Myeloma Mentorship Program
  • Member, Sigma Theta Tau International Society of Nursing, and Charter Memberships Delta XI, Kent
  • State University and Mu Omega, Purdue University

Honors & Awards

  • Best Practice Award, Platinum Level for Taussig Pain Management Team, Cleveland Clinic, July 2013
  • Mary Nowtny Excellence in Cancer Nursing Education, Oncology Nursing Society, 2011
  • Inductee, International Association of Nurses, 2011
  • Who’s Who in American Nursing, Society of Nursing Professionals, 1990-1991 edition

Contact Information

Cleveland Clinic
9500 Euclid Avenue / MC G-70-71
Cleveland, Ohio 44195