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Neuromuscular

The following clinical studies are available to patients with the corresponding muscle and nerve diseases. Please contact the appropriate person if you are interested in participating in the clinical study.

Amyotrophic Lateral Sclerosis (ALS)
  • Collection of Data and Biomaterial for Repository Banking to facilitate Research into the Etiology of ALS and related Motor Neuron Diseases
    Patients with Amyotrophic Lateral Sclerosis and healthy volunteers (controls) may be eligible to participate in this study. This trial involved one site visit, one blood draw, and a questionnaire. Additional inclusion and exclusion criteria apply. If you have any questions, or would like more information concerning this trial, please contact Tatyana Fernand, NP at 216.444.0055 or toll free 800.223.2273 ext. 40055. [Patient enrollment requirements have been met. Currently actively enrolling control subjects]
  • Clinical Trial of Ceftriaxone in Subjects With Amyotrophic Lateral Sclerosis (ALS)
    Participants will be randomly assigned to receive treatment with ceftriaxone or placebo for at least 12 months. Two thirds of participants will receive ceftriaxone and one third will receive placebo. This is a blinded study, so neither participants nor study staff will know which treatment a participant is receiving. Ceftriaxone is approved by the U.S. Food and Drug Administration (FDA) for treating bacterial infections but not for treating ALS. Also, ceftriaxone has not been given to people over a long period of time, such as months or years. If you have any questions, or would like additional information concerning this trial, please contact Nicole Berry, Research Coordinator, at 216.445.1741 or toll free 800.223.2276 ext. 51741.

Seeking Healthy Research Volunteers 60 Years and Over

Study title:The Significance of the Absent Leg Nerve Response on EMG in the Healthy Elderly

Help determine nerve response values in the leg for patients over the age of 60 as measured by an EMG nerve test.

Research patients will undergo a limited EMG of the leg, skin biopsy, bloodwork, and autonomic laboratory studies. Total participation time should not exceed 3 hours and can be completed within one to two clinic visits. The cost of all testing will be covered by the research study, including parking fees.

You CANNOT be in the study if you have the following:

  1. Numbness, tingling, or weakness in the legs/feet
  2. A history of a peripheral neuropathy or nerve disease
  3. Diabetes
  4. B12 deficiency
  5. A history of chemotherapy for cancer
  6. A family history of nerve disease not related to diabetes
  7. You are on coumadin

This study is being conducted by Dr. Jinny Tavee and Dr. Kerry Levin at the Cleveland Clinic Neurological Institute. For more information, call Dr. Jinny Tavee 216.445.2653.

A Multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of IGIV chromatography (IGIV-C) 10% treatment in subjects with chronic inflammatory Demyelinating Polyneuropathy (Bayer Health Care, Biologics Products Division).