Taussig Cancer Institute Awarded $2 Million in Stimulus Funds for Cancer Research Lab Renovation
Taussig Cancer Institute has been awarded more than $2 million from the American Recovery and Reinvestment Act (ARRA) for the renovation and expansion of its translational cancer research facilities. The National Center for Research Resources, part of the National Institutes of Health, awarded the grant, which will create 17 new jobs.
Dr. Lindner Receives Department of Defense Exploration-Hypothesis Development Award for MDS Research
Dr. Daniel Lindner, M.D., Ph.D. received the Exploration-Hypothesis Development Award for a study titled "Complementation of Myelodysplastic Syndrome Clones with Lentivirus Expression Libraries."
In this study, bone marrow cells from patients with Myelodysplastic syndrome (MDS) will be infected with engineered lentivirus that carries a genetic library. That is, each virus caries a single normal human gene. Infection of the patient's MDS cells with virus in culture will result in overexpression of a single, random normal human gene in each of the MDS cells.
If the experiment works, some lentivirus-infected MDS cells will recover the ability to grow and differentiate normally. Researchers will screen for these “recovered” MDS cells and hope to identify the gene(s) that “correct” the behavior of the abnormal MDS cells.
Viruses as a Potential Cause of Bone Marrow Cancers & Other Blood Disorders
In September 2009, Jaroslaw Maciejewski, MD, PhD, Chairman of the Department of Translational Hematology and Oncology Research, received a five-year, $1.9 million grant from the National Institutes of Health (NIH) to help fund his research of viruses as a potential cause of certain types of bone marrow cancers and other blood disorders.