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CASE 16112   |   12-1352
Association between Mammostrat score and pathologic response to neoadjuvant chemotherapy in Estrogen Receptor positive (ER+) early stage breast cancer

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  1. The primary objective of this study is to assess whether the Mammostrat test is predictive of response to chemotherapy by determining whether there is an association between Mammostrat score on preoperative breast cancer tissue and pCR rate to NAC.
  1. Preoperative Mammostrat scores will also be correlated with residual tumor burden as measured pathologically after NAC.

Inclusion Criteria
  1. Patients with ER-positive clinical stage I-III breast cancer who received NAC
  2. Core biopsy tissue must be available at CCF
  3. Surgical pathology specimen from definitive surgery (mastectomy or partial mastectomy) must also be available.

Exclusion Criteria
  1. Patients for whom adequate clinical records or adequate tissue samples are unavailable are excluded.

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