Appointments

Request an Appointment

Cancer Answer Line:
866.223.8100

M-F 8 a.m. - 4:30 p.m. ET

Expand Content

View Cancer Clinical Trials

ADL 1112   |   12-475
Automated Systems for Detection and Molecular Characterization of Circulating Tumor Cells

Disease(s)
Breast
Hospital(s)
Main Campus
Phase(s)
N/A
Stage(s)
Type(s)
Therapeutic
Drug(s)

Contact Information
Cancer Answer Line

866.223.8100

8:00 am - 4:30 pm, Monday - Friday


Description
  1. Primary
    • Determine the clinical performance of CTCscope and compare it with the FDA-approved CellSearch system
    • Molecular phenotyping of CTCs for targeted therapy

Inclusion Criteria
  1. The principle inclusion criteria are progressive, measurable metastatic breast cancer with their primary tumor HER2 status known. Prior adjuvant therapy, treatment of metastatic disease, or both are all permitted. We will be focusing on clinical validation of the automated CTCscope system, not proving its clinical utility that would require substantially more resources and longer time frame beyond the scope of this proposal.
  2. The age range is expected to be that of the natural age related incidence of breast cancer. The mean age of participants accrued in the current study is assumed to be approximately 55 with a range 31 to 79.
  3. The mental and physical health status will be such that patients would be able to understand and approve informed consent. Patients must consent to be in the study and must have signed an approved consent form that conforms to federal and institutional guidelines.
  4. Patient must have radiologic or histologic evidence of metastatic breast cancer.
  5. Hemoglobin > 8.5 gm percent
  6. Hematocrit > 25.5 percent
  7. Prior Treatment: No limitations. No medications will exclude patients from this study.

Exclusion Criteria
Exclusion Criteria Not Available

Cancer Answers & Appointments

Speak with a cancer nurse specialist for appointment assistance and for answers to your questions about cancer locally at 216.444.7923 or toll-free 1.866.223.8100.

Monday through Friday from 8 a.m. – 4:30 p.m. (ET).

Referrals

Resources for medical professionals

  • Outpatient appointment referrals: 216.444.7923 or 866.223.8100
  • Inpatient hospital transfers: 800.553.5056
  • Referring Physician Concierge: 216.444.6196 or 216.312.4910.

Clinical Trials

Search available cancer clinical trials by disease, hospital, phase or number.

This information is provided by Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition.

© Copyright 2014 Cleveland Clinic. All rights reserved.