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About Outcomes Research

About Outcomes Research

The Department of Outcomes Research was founded by Daniel Sessler, MD in 2005 and now has more than 45 permanent members, including 23 attending physicians, 18 research fellows, five statisticians, and regulatory coordinators. It is the largest single-center clinical research group in the field of anesthesiology.

The Department supports every aspect of clinical research, including sample-size estimates, trial coordination, data handling, statistical analysis, and regulatory functions. Most importantly, it provides academic collaboration and assistance with study design and execution for investigator-initiated research. As part of Cleveland Clinic, the Department is non-profit with the mission of “Providing the evidence for evidence-based medicine.”

The Department’s mission is to be acknowledged as the world’s leading clinical anesthesia research site. We aspire to:

  • Publish more high-impact, peer-reviewed clinical research papers (quantified as number multiplied by impact) than any other anesthesia department.
  • Recruit more extra-mural clinical research funding than any other anesthesia department, with “clinical research” being defined as research conducted with human subjects.
  • Train clinical investigators, including residents, fellows, and staff throughout Cleveland Clinic's healthcare system.

The Department on average published a full peer-reviewed paper per week. This makes it by far the world's most prolific clinical anesthesia research site.


Daniel Sessler, MD
Daniel Sessler, MD

Michael Cudahy Professor & Chair
Cleveland Clinic
9500 Euclid Ave — P77
Cleveland, OH 44195
Phone: 216.444.4900
Fax: 216.444.6135

Dr. Daniel Sessler attended medical school at Columbia University, and subsequently completed pediatric and anesthesia residencies at the University of California, Los Angeles.

The Outcomes Research Collaboration, which Dr. Sessler founded, includes 120 investigators in more than 20 countries. The Consortium currently coordinates more than 100 studies, including a dozen large, multi-center outcome trials. Dr. Sessler has published a book on therapeutic hypothermia and more than 600 full research papers; his papers have been cited more than 25,000 times.

Dr. Sessler has trained more than 100 research fellows, five of whom subsequently chaired departments of Anesthesiology. He has given lectures at more than 300 institutions and has been a principal or co-investigator on grants exceeding $35 million, more than half of which was from NIH and other peer-reviewed sources. Among his notable awards are a Fulbright Fellowship and the 2002 American Society of Anesthesiology Excellence in Research prize.

Dr. Sessler’s administrative work includes two stints as acting-chair of the Department of Anesthesiology at the University of Louisville. He was also Vice Dean and Associate Vice President for Health Affairs at the University of Louisville, granting him responsibility for research throughout the Health Sciences Campus. During his five years at the University of Louisville, he tripled the NIH funding to the Schools of Medicine, Dentistry, and Nursing.

Andrea Kurz, M.D.
Andrea Kurz, MD

Professor & Vice-Chair
Cleveland Clinic
9500 Euclid Ave — P77
Cleveland, OH 44195
Phone: 216.445.9924

Dr. Andrea Kurz attended the University of Vienna School of Medicine (1983–1987), and completed an anesthesia residency and fellowship at the University of Vienna (1987–1993). She became a research fellow in the Outcomes Research Consortium Laboratory in San Francisco and an Associate Professor in the Department of Anesthesia and Critical Care at the University of California in San Francisco (1993–1996).

She was Professor of Anesthesia in the Department of Anesthesia and General Intensive Care at the University of Vienna. Dr. Kurz was an Associate Professor of Anesthesia at Washington University in St. Louis for four years, where she directed the Department of Anesthesia Clinical Research Center.

Dr. Kurz went on to chair the Department of Anesthesiology at the University of Bern for four years, during a period of extraordinary research productivity for the Department. Dr. Kurz is now Vice-chair, Department of Outcomes Research at Cleveland Clinic.

Free CME Classes

Research Education

21 research fellows are fully immersed in all aspects of research in this two year commitment. In addition, 29 Cleveland Clinic residents have substantial involvement in one of our clinical research projects. Also, our department offers the Fundamentals of Clinical Research course, which is open to all Cleveland Clinic employees.

Research education is a top priority for the Department. Research topics include, but are not limited to: ethics, human subject protection, statistics, study design, data collection, abstract and manuscript composition, presentation, and participation in peer reviews of scientific submissions.

Additional opportunities for education through orientation sessions, weekly Fundamentals of Clinical Research Conferences, CA-1 Research Seminar and Annual Resident Research Day (featuring a distinguished visiting professor with recognized research credentials) are made available to residents within the program.

The academic productivity of our residents is encouraged and tracked using our Academic Portfolio, which incorporates complex literature, research skills, written presentation, and oral presentation. Teaching interventions encourage resident development to match resident expectations.

In addition to the education and support provided to the residents, a three-to-six month period of dedicated research in the Department of Outcomes Research is available to CA-3 residents. Residents choosing this option participate in data collection and are immersed into studies that give them a basic understanding of clinical research. Scheduled didactic education in research topics is reinforced through mentorship by the Department of Outcomes Research. Each resident who selects dedicated research time as a CA-3 is encouraged to present one or more abstracts and to co-author manuscripts in major journals.

Resident Presentations & Publications

Anesthesiology residents and fellows have the opportunity to participate in ongoing, productive, thematic research work. Each project is designed to maximize research experience. Residents can choose a research rotation in their third year of training, but many start earlier.

In addition to presenting their research work at regional and national meetings, our goal is to publish at least 20 full papers per year with resident co-authors.