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Cancer Research

Cleveland Clinic Florida's Cancer Research staff is dedicated to providing patients innovative therapies through clinical research trials which include new targeted agents and therapies. Cancer specialists from The Maroone Cancer's Departments of Hematology and Oncology serve as principal investigators for the trials, working closely with the research staff and collaborating with the world-renowned Taussig Cancer Institute at Cleveland Clinic in Ohio. Cleveland Clinic Florida also participates in many clinical trials with the National Cancer Institute.

For more information about our clinical trials, please contact:
Abel Rodriguez, Clinical Research Supervisor
Phone: 954.487.2258

Areas of Cancer Clinical Trials

Breast Cancer

BERENICE: A Multicenter, Multinational, Phase II Study to Evaluate Pertuzumab in Combination With Trastuzumab and Standard Neoadjuvant Anthracycline-based Chemotherapy in Patients With HER2-Positive, Locally Advanced, Inflammatory, or Early-Stage Breast Cancer

A Phase 2 Double-Blinded, Randomized, Placebo- Controlled Study of Indoximod in Combination with a Taxane Chemotherapy in Metastatic Breast Cancer

A Phase III Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less.

A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer.

Frequency and Clinical Spectrum of Germline PTEN Mutations in a Hospital Population Bases Series of Incident Breast Cancer Cases

  • Sponsor Study Number: CASE 2107
  • Cleveland Clinic Study Number: IRB CC302
  • Principal Investigator: Thomas Samuel, MD

Molecular Mechanisms Involved in Cancer Predisposition

  • Cleveland Clinic Study Number: IRB 8458
  • Principal Investigator: Charis Eng, MD / Asheley Supik, MS, CGC
Colon Cancer

A Phase III Trial Of 6 Versus 12 Treatments Of Adjuvant Folfox Plus Celecoxib Or Placebo For Patients With Resected Stage III Colon Cancer


A Randomized Phase II Study of Co-Expression Extrapolation (COXEN) With Neoadjuvant Chemotherapy for Localized, Muscle-Invasive Bladder Cancer

Lung Cancer
Prostate Cancer