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Mary E. Rayborn, M.S.

  1. Smelser, G.K., V. Ozanics, M.E. Rayborn and D. Sagun (1973) The fine structure of the retinal transient layer of Chievitz. Invest. Ophthalmol. 12:504-512.

  2. Smelser, G.K., V. Ozanics, M.E. Rayborn and D. Sagun (1974) Retinal synaptogenesis in the primate. Invest. Ophthalmol. 13:340-361.

  3. Ozanics, V., M.E. Rayborn and D. Sagun (1976) Some aspects of corneal and scleral differentiation in the primate. Exp. Eye Res. 22:305-327.

  4. Bridges, C.D., J.G. Hollyfield, J.C. Besharse and M.E. Rayborn (1976) Visual pigment loss after light induced shedding of rod outer segments. Exp. Eye Res. 23:673-641.

  5. Hollyfield, J.G., J.C. Besharse and M.E. Rayborn (1976) Effect of light on the quantity of phagosomes in the pigment epithelium. Exp. Eye Res. 23:623-635.

  6. Ozanics, V., M.E. Rayborn and D. Sagun (1977) Observations on the morphology of the developing primate cornea: Epithelium, its innervation and anterior stroma. J. Morph. 153:263-298.

  7. Hollyfield, J.G., J.C. Besharse and M.E. Rayborn (1977) Variations in the phagosome content of the pigment epithelium in relationship to cyclic lighting. Atti G. Ronchi 32:309-313.

  8. Lolley, R.N., D.B. Farber, M.E. Rayborn, and J.G. Hollyfield (1977) Accumulation of cyclic guanosine monophosphate causes degeneration of photoreceptor cells: Simulation in normal retina of an inherited disease. Science 196:664-666.

  9. Besharse, J.C., J.G. Hollyfield and M.E. Rayborn (1977) Photoreceptor outer segments: Accelerated membrane renewal in rods after light exposure. Science 196:536-537.

  10. Hollyfield, J.G., J.C. Besharse and M.E. Rayborn (1977) Turnover of rod photoreceptor outer segments: Membrane addition and loss in relationship to temperature. J. Cell Biol. 75:490-506.

  11. Besharse, J.C., J.G. Hollyfield and M.E. Rayborn (1977) Turnover of rod photoreceptor outer segments: Membrane addition and loss in relationship to light. J. Cell Biol. 75:507-527.

  12. Ozanics, V., M.E. Rayborn and D. Sagun (1978) Observations on the ultrastructure of the developing primate choroid coat. Exp. Eye Res. 26:25-45.

  13. Currie, J., J.G. Hollyfield and M.E. Rayborn (1978) Rod outer segments elongate in constant light: Darkness is required for normal shedding. Vis. Res.18:995-1004.

  14. Hollyfield, J.G. and M.E. Rayborn (1978) Photoreceptor outer segment development: Light and dark regulate the rate of membrane addition and loss. Invest. Ophthalmol. Vis. Sci. 18:117-132.

  15. Hollyfield, J.G., M.E. Rayborn, P.V. Sarthy and D.M.K. Lam (1979) The emergence, localization and maturation of neurotransmitter systems during development of the retina in Xenopus laevis. I. g-aminobutyric acid. J. Comp. Neurol. 188:587-598.

  16. Hollyfield, J.G., M.E. Rayborn and S.F. Basinger (1980) Membrane turnover in rod outer segments: Changing patterns of shedding after extended periods of constant light and darkness. In: The Effects of Constant Light on Visual Processes (Williams and Baker editors), Plenum Publishing Corp, pp. 389-400.

  17. Hollyfield, J.G., M.E. Rayborn, P.V. Sarthy and D.M.K. Lam (1980) Retinal development: Time and order of appearance of specific neuronal properties. Neurochem. 1:93-101.

  18. Hollyfield, J.G., M.E. Rayborn and D.L. Medford (1980) Damaging effects of constant light and darkness on the retina of the frog, Rana pipiens. In: The Effect of Constant Light on the Visual Process (Williams and Baker, editors), Pergamon Press, pp. 401-407.

  19. Lolley, R.N., M.E. Rayborn, J.G. Hollyfield and D.B. Farber (1980) Cyclic GMP and visual cell degeneration in the inherited disorder of rd mice: A progress report. Vis. Res. 20:1157-1161.

  20. Rayborn, M.E., P.V. Sarthy, D.M.K. Lam and J.G. Hollyfield (1981) The emergence, localization and maturation of neurotransmitter systems during development of the retina in Xenopus laevis II. Glycine. J. Comp. Neurol. 195:585-593.

  21. Sarthy, P.V., M.E. Rayborn, J.G. Hollyfield and D.M.K. Lam (1981) The emergence, localization and maturation of neurotransmitter systems during development of the retina in Xenopus laevis. III. Dopamine. J. Comp. Neurol. 195:595-602.

  22. Hollyfield, J.G., M.E. Rayborn, D.B. Farber and R.N. Lolley (1982) Selective photoreceptor degeneration during retinal development: The role of altered phosphodiesterase activity and increased levels of cyclic nucleotides. In: Structure of the Eye (Hollyfield, editor) Elsevier North Holland, Inc., pp. 97-114.

  23. Hollyfield, J.G. and M.E. Rayborn (1982) Membrane assembly in photoreceptor outer segments: Progressive increase in open basal discs with increased temperature. Exp. Eye Res. 34:115-119.

  24. Hollyfield, J.G., M.E. Rayborn, G.E. Verner and M.B. Maude (1982) Membrane addition to rod photoreceptor outer segments: Light stimulates membrane assembly in the absence of increased membrane biosynthesis. Invest. Ophthalmol. Vis. Sci. 22:417-427.

  25. Hollyfield, J.G., J.M. Frederick, D.M.K. Lam, and M.E. Rayborn (1982) The appearance of specific neuronal properties during the development of photoreceptors and horizontal cells in Xenopus laevis. In: Visual Cells in Evolution (Jane A. Westfall, editor) Raven Press, New York, pp. 57-64.

  26. Frederick, J.M., M.E. Rayborn, A.M. Laties, D.M.K. Lam and J.G. Hollyfield (1982) Dopaminergic neurons in the human retina. J. Comp. Neurol. 210:65-79.

  27. Rayborn, M.E., L.C. Moorhead, and J.G. Hollyfield (1982) A dominantly inherited chorioretinal degeneration resembling sectoral retinitis pigmentosa. Ophthalmol. 89:1441-1454.

  28. Anderson, R.E., M.B. Maude, P.A. Kelleher, M.E. Rayborn and J.G. Hollyfield (1982) Phosphoinositide metabolism in the retina: Localization to horizontal cells and regulation by light and divalent cations. J. Neurochem. 41:764-771.
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  29. Moorhead, L.C., M.E. Rayborn, R.P. Borda, C.A. Garcia and J.G. Hollyfield (1982) Chorioretinal degeneration resembling sector retinitis pigmentosa: A clinical and histopathological study. Proceedings of the XXIV International Congress of Ophthalmology. 1:463-469.

  30. Hollyfield, J.G., J.M. Frederick and M.E. Rayborn (1983) Neurotransmitter properties of the newborn human retina. Invest. Ophthalmol. Vis. Sci. 24:893-897.

  31. Hollyfield, J.G., M.E. Rayborn and J. Rosenthal (1984) Two populations of rod photoreceptors in the retina of Xenopus laevis identified with 3H-fucose autoradiography. Vis. Res. 24:777-782.

  32. Frederick, J.M., M.E. Rayborn and J.G. Hollyfield (1984) Glycinergic neurons in the human retina. J. Comp. Neurol. 226:159-172.

  33. ollyfield, J.G., S.J. Fliesler, M.E. Rayborn, S.L. Fong, R.A. Landers and C.D. Bridges (1985) Synthesis and secretion of interstitial retinol-binding protein by the human retina. Invest. Ophthalmol. Vis. Sci. 26:58-67.
  34. Fliesler, S.J., M.E. Rayborn, and J.G. Hollyfield (1985) Membrane morphogenesis in retinal rod outer segments: Inhibition by tunicamycin. J. Cell Biol 100:574-587.

  35. Frederick, J.M., M.E. Rayborn, L.C. Moorhead and J.G. Hollyfield (1985) Retinitis pigmentosa: correlative studies of histopathology and in vitro retinal metabolism in an autosomal dominant chorioretinal degeneration. In: Research in Retinitis Pigmentosa: Advances in the Biosciences (Zrenner, Krastel and Goedel, editors) Pergamon Press, pp. 367-380.

  36. Hollyfield, J.G., H.H. Varner, M.E. Rayborn, G.I. Liou, and C.D. Bridges (1985) Endocytosis and degradation of interstitial retinol-binding protein: Differential capabilities of cells that border the interphotoreceptor matrix. J. Cell Biol. 100:1676-1681.

  37. Hollyfield, J.G., M.E. Rayborn, R.J. Ulshafer and S.J. Fliesler (1985) Simulation of an inherited disease in the normal retina. Involvement of cyclic nucleotides. In: Retinal Degeneration: Experimental and Clinical Studies (LaVail, Hollyfield and Anderson, editors) Alan R. Liss, New York, pp. 341-348.

  38. Rayborn, M.E., J.M. Frederick, R.J. Ulshafer, G.A. Tabor, L.C. Moorhead and J.G. Hollyfield (1985) Histopathology and in vitro metabolic studies on tissues from a family with an autosomal dominant form of retinitis pigmentosa. In: Retinal Degeneration: Experimental and Clinical Studies (LaVail, Hollyfield and Anderson, editors) Alan R. Liss, New York, pp. 37-49.

  39. Fliesler, S.J., L.M. Rapp, M.E. Rayborn and J.G. Hollyfield (1985) Defects in retinal glycoprotein metabolism: Putative role in photoreceptor degeneration. In: Retinal Degeneration: Experimental and Clinical Studies (LaVail, Hollyfield and Anderson, editors) Alan R. Liss, New York, pp. 349-371.

  40. Hollyfield, J.G., S.J. Fliesler, M.E. Rayborn and C.D. Bridges (1985) Rod photoreceptors in the human retina synthesize and secrete interstitial retinol-binding protein. In: Interphotoreceptor Matrix in Health and Disease (Bridges and Adler, editors). Alan R. Liss, New York, pp. 141-149.

  41. Hollyfield, J.G., H.H. Varner, M.E. Rayborn, and C.D. Bridges (1985) Participation of photoreceptor cells in retrieval and degradation of components in the inter photoreceptor matrix. In: Interphotoreceptor Matrix in Health and Disease (Bridges and Adler, editors) Alan R. Liss, New York, pp. 171-175.

  42. Fliesler, S.J., M.E. Rayborn and J.G. Hollyfield (1986) Inhibition of oligosaccharide processing and membrane morphogenesis in retinal rod photoreceptor cells. Proc. Nat. Acad. Sci. USA 83:6435-6439.

  43. Fliesler, S.J., M.E. Rayborn and J.G. Hollyfield (1986) Protein-bound carbohydrate involvement in plasma membrane assembly: The retinal rod photoreceptor cell as a model. In: Protein-Carbohydrate Interactions in Biological Systems, Academic Press, Inc., London, pp. 191-205.

  44. Varner, H.H., M.E. Rayborn, A.M. Osterfeld and J.G. Hollyfield (1987) Localization of proteoglycan within the matrix sheath of cone photoreceptors. Exp. Eye Res. 44:633-642.

  45. Hollyfield, J.G. and M.E. Rayborn (1987) Endocytosis in the inner segment of rod photoreceptors: Analysis of Xenopus laevis retinas using horseradish peroxidase. Exp. Eye Res. 45:703-719.

  46. Hollyfield, J.G., M.E. Rayborn and R.A. Landers (1990) A technique for isolation of the photoreceptor layer from other neurons in the human retina. Exp. Eye Res. 50:335-338.

  47. Hollyfield, J.G., M.E. Rayborn, R.A. Landers and K.M. Myers (1990) Insoluble interphotoreceptor matrix domains surround rod photoreceptors in the human retina. Exp. Eye Res. 51:107-110.

  48. Hollyfield, J.G., H.H. Varner and M.E. Rayborn (1990) Regional variations within the interphotoreceptor matrix from fovea to the retinal periphery. Eye 4:333-339.

  49. Iwasaki, M., M.E. Rayborn, A. Tawara and J.G. Hollyfield (1992) Proteoglycans in the mouse interphotoreceptor matrix. V. Distribution at the apical surface of the pigment epithelium before and after retinal separation. Exp. Eye Res. 54:415-432.

  50. Tien, L., M.E. Rayborn and J.G. Hollyfield (1992) Characterization of the interphotoreceptor matrix surrounding rod photoreceptors in the human retina. Exp. Eye Res. 55:297-306.

  51. Iwasaki, M., K.M. Myers, M.E. Rayborn and J.G. Hollyfield (1992) Interphotoreceptor matrix in the human retina. Cone-like domains surround a small population of rod photoreceptors. J. Comp. Neurol. 319:277-284.

  52. Gonzales-Fernandez, F., K.L. Kittredge, M.E. Rayborn, J.G. Hollyfield, R.A. Landers, M. Saha and R.M. Grainger (1993) Interphotoreceptor retinoid-binding protein (IRBP), a major 124kD glycoprotein in the interphotoreceptor matrix of Xenopus laevis: Characterization, molecular cloning and biosynthesis. J. Cell Sci. 105:7-21.

  53. Stiemke, M.M., R.A. Landers, M.R. Al-Ubaidi, M.E. Rayborn and J.G. Hollyfield (1994) Photoreceptor outer segment development in Xenopus laevis: Influence of the pigment epithelium. Dev. Biology 162:169-180.

  54. Landers, R.A., M.E. Rayborn, K.M. Myers and J.G. Hollyfield (1994) Increased retinal synthesis of heparan sulfate proteoglycan and HNK-1 glycoproteins following photoreceptor degeneration. J. of Neurochem. 63:737-750.

  55. Kamei, M., S.S. Apte, M.E. Rayborn, H. Lewis and J.G. Hollyfield (1997) TIMP-3 accumulation in Bruch's membrane and drusen in eyes from normal and age-related macular degeneration donors. Degenerative Retinal Diseases, Plenum Press, p. 11-16, New York, 1997.

  56. Rayborn, M.E., K.M. Myers and J.G. Hollyfield (1997) Photoreceptor rosettes in age-related macular degeneration donor tissues. Degenerative Retinal Diseases, Plenum Press, p. 17-22, New York, 1997.

  57. Hollyfield, J.G., M.E. Rayborn and R. Tammi (1997) Hyaluronan localization in tissues of the mouse posterior eye wall: Absence in the interphotoreceptor matrix. Exp. Eye Res. 65:603-608.

  58. Hollyfield, J.G., M.E. Rayborn and R. Tammi (1998) Hyaluronan in the interphotoreceptor matrix of the eye: Species differences in content distribution, ligand binding and degradation. Exp. Eye Res. 66:241-248.

  59. Acharya, S., M.E. Rayborn and J.G. Hollyfield (1998) Characterization of a SialoProtein Associated with Cones and Rods (SPACR) in the Interphotoreceptor Matrix of the Human Retina: Immunological and Carbohydrate Analysis. Glyco Biol. 8:997-1006.

  60. Hollyfield, J.G., M.E. Rayborn, R. Midura, K. Shadrach, and S. Acharya. (1999) Chondroitin sulfate proteoglycan core protein in the interphotoreceptor matrix: a comparative study using biochemical and immunocytochemical analysis. Exp. Eye Res. 69: 311-322.

  61. Acharya, S., V. Foletta, M.E. Rayborn, I.R. Rodriguez, S.W. Young III, and J.G. Hollyfield (1999) Spacrcan, a novel human hyaluronan binding proteoglycan synthesized by photoreceptors and pinealocytes. J. Biol. Chem. 27: 56945-6955.

  62. Hollyfield, J., M.E. Rayborn, S. Acharya (1999) Organization of the interphotoreceptor matrix: Binding of SPACR to hyaluronan. In: Retinal Degenerative Diseases and Experimental Therapy, Eds. Joe G. Hollyfield et al., Plenum Press N, p.443-448,.

  63. Acharya, S., V. Foletta, J.W. Lee, M.E. Rayborn, I. Rodriguez, S. Young III, J.G. Hollyfield (2000 ) SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes. J. Biol. Chem. 275:6945-66955.

  64. Lee, J.W., Q. Chen, M. E. Rayborn, K. Shadrach, J. Crabb. I. Rodriguez, J.G. Hollyfield (2000) SPACR in the interphotoreceptor matrix of the mouse retina: molecular, biochemical and immunohistochemical characterization. Exp. Eye Res. 71(4):341-52.

  65. Marmorstein, A., L. Marmorstein, M. E. Rayborn, X. Wang, J. Hollyfield, K. Petrukhin (2000) Bestrophin, the product of Best Vitelliform Macular Dystrophy gene (VMD2) localizes to the basolateral membrane of the retinal pigment epithelium where it can affect the electro-oculogram. Proc. Nat. Acad. Sci. USA 97(23):12758-63.

  66. Hollyfield, J.G., M.E. Rayborn, P. deS. Senanayake, and A. Calabro (2000) Hyaluronan is the organization scaffold of the interphotoreceptor matrix of the retina. In: Retinal Degenerative Disease and Experimental Therapy, Eds. Joe G. Hollyfield et al. Plenum Press, New York.

  67. Hollyfield, J.G., M.E. Rayborn, K. Nishiyama, K. Shadrach, M. Miyagi, J. Crabb, I. Rodriguez (2001) Interphotoreceptor matrix of the fovea and peripheral retina in the primate Macaca mulatta: distribution and glycoforms of SPACR and SPACRCAN. Exp. Eye Res. 72(1):49-61.

  68. Hollyfield, J.G., M.E. Rayborn, P.deS. Senanayake, and A. Calabro (2001) Hyaluronan is the organization scaffold of the interphotoreceptor matrix of the retina. Retinal Degenerative Disease and Experimental Therapy, Plenum Press, New York, in press

  69. Foletta, V.C., K. Nishiyama, M.E. Rayborn, K.G. Shadrach, W.S. Young and J.G. Hollyfield (2001) SPACRCAN in the developing retina and pineal gland of the rat: spatial and temporal pattern of gene expression and protein synthesis. J. Comp. Neurol, 435:354-365.

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