CURRENTLY RECRUITING
The following studies are currently enrolling. All studies have been approved by the Institutional Review Board.
Genetics
Studies of the Molecular Genetics of Eye Diseases
Objective: To map the genes for inherited eye diseases. To screen candidate genes for mutations in a variety of genetic ocular disorders, including ocular malformations, congenital cataracts and retinal dystrophies.
Contact: E. Traboulsi, M.D., at (216) 444-4363 or S. Crowe, C.O.T., at (216) 445-3840
The Genetics of Strabismus
Objective: To discover the genes that cause some strabismus syndromes, including those for accommodative esotropia, congenital esotropia, congenital ocular fibrosis syndrome, intermittent exotropia, Brown syndrome and Duane syndrome.
Contact: E. Traboulsi, M.D., at (216) 444-4363 or S. Crowe, C.O.T., at (216) 445-3840
Pediatrics
Amblyopia Treatment Study (ATS5): A Randomized Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children 3 to <7 Years Old
Objective: The Amblyopia Treatment Study is a two-part study. The first part is being conducted to determine whether wearing glasses can improve amblyopia. The second part is being conducted to determine whether patching treatment improves amblyopia. Two hours of patching the sound eye combined with at least one hour of near work will be compared with a control group which will wear glasses only. The study is funded by the National Eye Institute and is coordinated by the JAEB center for Health Research, a nonprofit clinical research center. The Pediatric Eye Investigator Group includes pediatric optometrists and pediatric ophthalmologists.
Contact: D. Tucker, O.D., or A. Marcotty, M.D., at (216) 831-0120 or L. Slaby, C.O.A., at (330) 963-4843
Infant Aphakia Treatment Study
Objective: To determine whether infants with a unilateral congenital cataract are more likely to develop better vision following cataract extraction surgery if (1) they undergo the primary implantation of an IOL or if (2) they are treated primarily with a contact lens.
Contact: E. Traboulsi, M.D., at (216) 444-4363 or S. Crowe, C.O.T., at (216) 445-3840
