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Details

Title Cytokine Induced Gene Expression

IRB 3164

Hospital Main Campus

Disease Advanced Disease

Description

Description

  1. Primary
    • To obtain data for the genes induced by interferons (IFNs), chemotherapy drugs, and cytokines in tumor cells and immune cells in cancer patients and healthy volunteers.
    • To ascertain differing patterns of gene and tumor response that occur with different interferons, cytokines and chemotherapy drugs.
Inclusion Criteria

Inclusion Criteria

  1. Patients must have a clinical and/or a histological diagnosis of malignancy.
  2. Age ≥ 18 years
  3. All patients must be informed of the investigational nature of this study and must provide written informed consent in accordance with institutional and federal guidelines.
Exclusion Criteria

Exclusion Criteria

  1. Patients who are known to be HIV, or HBsAg positive.
  2. No patient may have a second malignancy other than the following exceptions:
    • Basal cell carcinoma ofthe skin.
    • Carcinoma in-situ of the uterine cervix.
    • Any malignancy treated with curative intent and in complete remission for ≥ 3 years.