Joseph Cacchione, MD


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Joseph Cacchione, MD
Department: Heart and Vascular Institute
Chair, Operations and Strategy
Location: Cleveland Clinic Main Campus
Mail Code J2-3
9500 Euclid Avenue
Cleveland, OH 44195
Joseph Cacchione, MD
Department: Cardiovascular Medicine
Location: Cleveland Clinic Main Campus
Mail Code J2-3
9500 Euclid Avenue
Cleveland, OH 44195
Type of Doctor:
Adults Only

Biographical Sketch

Joseph G. Cacchione, MD, FACC, is an interventional cardiologist in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine in the Arnold and Sydell Miller Family Heart & Vascular Institute. He also is Chairman of Operations and Strategy at Cleveland Clinic.

A graduate of Hahnemann University School of Medicine in Philadelphia, Dr. Cacchione served his internship and residency at University Hospitals of Cleveland and a fellowship in clinical cardiology at the University of Rochester, Strong Memorial Hospital in Rochester, NY. He returned to University Hospitals for a one-year research fellowship followed by a one-year fellowship in interventional cardiology, which he completed in 1991. In 2007 he earned Executive Certification at the University of Chicago Graduate School of Business.

Dr. Cacchione's clinical interests include coronary artery disease, heart attack, chest pain and ischemic cardiomyopathy (enlarged heart). He has participated in more than two dozen research projects related to new treatments for chest pain, heart attack and coronary artery disease.  Dr. Cacchione's research has been published in many notable cardiology journals, including Journal of the American College of Cardiology, American Heart Journal and Circulation.

Prior to his appointment to the Cleveland Clinic staff in 2009, Dr. Cacchione was in private cardiology practice and on the cardiology staff at St. Vincent Health Center in Erie, Pa. From 1991 through 2008.

Reflecting his interest in promoting healthcare quality, Dr. Cacchione also has held a number of administrative positions. In the medical arena these have included Chief Quality Officer for Saint Vincent Health System, Chief of the Division of Cardiology, Director of the Cardiac Catheterization Lab and Vice Chairman of the Critical Care Committee at St. Vincent Health Center.

Dr. Cacchione has been an active member of the American College of Cardiology for 15 years.  He is a member of many committees and task forces, including the Payment Reform Taskforce, Clinical Quality Committee, Quality in Technology Work Group and Chair of Partner in Quality.  Dr. Cacchione has recently been named to the prestigious position of ACC Board of Trustees.

Dr. Cacchione is a Fellow of the American College of Cardiology, the American College of Healthcare Executives and the American Medical Association. He is board-certified in cardiovascular medicine and interventional cardiology.

Education & Fellowships

Fellowship - University Hospitals of Cleveland
Interventional Cardiology
Cleveland, OH USA
Research Fellowship - University Hospitals of Cleveland
Cardiovascular Disease
Cleveland, OH USA
Fellowship - Strong Memorial Hospital of The University of Rochester
Clinical Cardiology
Rochester, NY USA
Residency - University Hospitals of Cleveland
Internal Medicine
Cleveland, OH USA
Internship - University Hospitals of Cleveland
Internal Medicine
Cleveland, OH USA
Medical School - Hahnemann University Medical College
Philadelphia, PA USA
Undergraduate - Gannon University
Erie, PA USA


  • Internal Medicine
  • Internal Medicine- Cardiovascular Disease
  • Internal Medicine- Interventional Cardiology

Specialty Interests

Angina, Coronary Artery Disease, Angioplasty, Cardiac Catheterization, Coronary Stenting

Treatment & Services

  • Abnormal Stress Test
  • Angiography
  • Angioplasty
  • Atherectomy
  • Cardiovascular Medicine Department
  • Coronary Artery Atherectomy
  • Coronary Balloon Angioplasty (PTCA)
  • Coronary Intervention
  • C-Reactive Protein Testing
  • Drug Eluting Stenting
  • FFR determination
  • General Cardiology
  • Intervention Section
  • Intra-aortic Balloon Pumping
  • Rotational Atherectomy
  • Stents
  • Stress Testing

Specialty in Diseases and Conditions

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. The Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 5/23/2014, Dr. Cacchione has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Fiduciary Role. Dr. Cacchione serves in a fiduciary capacity, such as an elected officer, director or chief medical officer, for the following companies or other entities:

  • Cadence Health
  • INRange Systems, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English