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Brian Rini, MD


Brian Rini, MD
Department: Hematology and Oncology
Location: Cleveland Clinic Main Campus
Mail Code R35
9500 Euclid Avenue
Cleveland, OH 44195
Brian Rini, MD
Department: Urology
Location: Cleveland Clinic Main Campus
Mail Code R35
9500 Euclid Avenue
Cleveland, OH 44195
Type of Doctor:
Adults Only

Biographical Sketch

Brian I. Rini, MD, is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University in Cleveland, Ohio. A Staff member of the Department of Solid Tumor Oncology, Dr. Rini’s work focuses on genitourinary malignancies.

Dr. Rini earned his medical degree at the Ohio State University College of Medicine in Columbus, Ohio. After completing a residency program in internal medicine at University of Chicago Hospitals in Illinois, Dr. Rini was awarded a fellowship in hematology and oncology at the University of Chicago. Dr. Rini was an Assistant Professor at the University of California San Francisco before moving to Cleveland Clinic.

At Cleveland Clinic, Dr. Rini’s primary research has been in renal cell carcinoma (RCC) and prostate cancer, with special focus on antiangiogenic therapy and immunotherapy. Dr. Rini’s research has been published in peer-reviewed journals that include Journal of the National Cancer Institute, Journal of Clinical Oncology, Cancer, Lancet and JAMA. He is a member of the editorial boards of Journal of Clinical Oncology, Cancer and British Journal of Urology.

Certified in Medical Oncology by the American Board of Internal Medicine, Dr. Rini is active in numerous professional organizations, including the American Society of Clinical Oncology (ASCO), American Association for Cancer Research and the Kidney Cancer Association National Medical Advisory Board. He serves on the ASCO Board of Experts and on the External Review Board for the ASCO Cancer Therapy Evaluation Program.

Education & Fellowships

Fellowship - University of Chicago Hospitals
Hematology / Oncology
Chicago, IL USA
Residency - University of Chicago Hospitals
Internal Medicine
Chicago, IL USA
Internship - University of Chicago Hospitals
Internal Medicine
Chicago, IL USA
Medical School - The Ohio State University College of Medicine and Public Health
Columbus, OH USA
Undergraduate - University of Notre Dame
Notre Dame, IN USA


  • Internal Medicine- Medical Oncology

Specialty Interests

Kidney cancer, renal cell cancer, prostate cancer, adrenal cancer, testicular cancer, bladder cancer, anti-angiogenic therapy, immunotherapy, clinical trials, cancer

Awards & Honors

  • Eugene P. Schonfeld Career Achievement Award (KCA) 2015
  • Sam and Maria Miller Professional Excellence Award (Clinical Research) 2011
  • ASCO/AACR Workshop on Methods in Clinical Cancer Research Merrill J. Egorin Outstanding Mentor Award  2011
  • Case Comprehensive Cancer Center Program Leader of the Year 2011
  • Solid Tumor Oncology Teacher of the Year 2011-2012
  • CCF Department of Molecular Cardiology Page Award for Best Publication 2012
  • Cleveland’s Best Doctors 2005-2015
  • Fellow in FACP 2009
  • CCF Research Programs Council Award Project: Immunoregulatory Effects of Cyclooxygenase-2 (COX-2) Expression in Renal Cell Carcinoma 2006, 2007
  • Department of Defense: New Investigator Award: CTLA-4 Blockade Based Immunotherapy in Prostate Cancer 2004
  • Illinois Medical Oncology Society. Best Submitted ASCO Abstract Award 2001
  • ASCO Abstract Merit Award: Rini BI et al.: Allogeneic Stem Cell Transplantation of Metastatic RCC after Non-myeloablative Chemotherapy 2001
  • ASCO/AACR Methods in Clinical Cancer Research workshop 1999


  • American Society of Clinical Oncology
  • American College of Physicians
  • American Urological Association
  • American Association of Cancer Research

Treatment & Services

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/13/2016, Dr. Rini has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Rini receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Pfizer, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English

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