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Apostolos Kontzias, MD


Apostolos Kontzias, MD
Department: Rheumatologic and Immunologic Disease
Location: Cleveland Clinic Main Campus
Mail Code A50
9500 Euclid Avenue
Cleveland, OH 44195
Apostolos Kontzias, MD
Department: Rheumatologic and Immunologic Disease
Location: Mentor Medical Office Building
Mail Code A50
7060 Wayside Drive
Mentor, OH 44060
Type of Doctor:
Adults Only

Biographical Sketch

Apostolos Kontzias, MD, is a Staff Physician in the Orthopedic and Rheumatologic Institute at Cleveland Clinic. Dr. Kontzias is also an Assistant Professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. Dr Kontzias has a research focus on autoinflammatory syndromes which are conditions of innate immunity frequently genetically inherited presenting with fever, rash and arthritis. He is the Director of the Autoinflammatory Clinic which operates within the The R. J. Fasenmyer Center for Clinical Immunology. He has established a biobank registry in collaboration with the Genomics Institute at the Cleveland Clinic and has forged national and international collaborations to study these conditions.

Education & Fellowships

Fellowship - National Institutes of Health
Bethesda, MD USA
Residency - Lincoln Medical and Mental Health Center
Internal Medicine
Bronx, NY USA
Medical School - University of Athens Faculty of Medicine, National & Kapodistrian
Athens Greece


  • Internal Medicine
  • Internal Medicine- Rheumatology

Specialty Interests

Autoinflammatory diseases Innate Immunity diseases Periodic Fever syndromes Fever of Unknown Origin Familial Mediterranean Fever TNF receptor associated periodic syndrome Cryopyrin associated periodic syndromes (Muckle Wells, Familial cold urticarial, NOMID) Adult onset Still's Disease Spondyloarthritis Ankylosing spondylitis

Treatment & Services

  • General Rheumatology
  • General Rheumatology including Lupus
  • Joint Aspiration
  • Medical Management of Early Osteoarthritis
  • Musculoskeletal Evaluation
  • Musculoskeletal Treatment For Joint Pain
  • Pericardial Diseases Center
  • Rheumatology

Specialty in Diseases and Conditions

  • Adult Onset Still's Disease
  • Antiphospholipid Syndrome
  • Arthritic Knee Problems
  • Arthritis
  • Arthritis of the Foot and Ankle
  • Arthritis Of The Hip
  • Arthritis Of The Knee
  • Autoinflammatory Syndromes
  • Blau Syndrome
  • Bursitis
  • Connective Tissue Diseases
  • Connective Tissue Disorders
  • Cryopyrin Associated Periodic Syndromes (CAPS)
  • Familial Cold Urticaria
  • Familial Mediterranean Fever
  • Familial Mediterranean Fever (FMF) Syndrome
  • Fever of Unknown Origin (FUO)
  • Hip Pain
  • Hyper IgD syndrome (HIDS)
  • Inflammatory Arthritis
  • Joint Disorders
  • Knee Joint Disorders
  • Knee Pain
  • Lupus
  • Majeed Syndrome
  • Muckle-Wells syndrome (MWS)
  • Musculoskeletal Disorders
  • Musculoskeletal Pain
  • Myositis
  • Osteoarthritis Of The Hips And Knees In The Elderly
  • Osteopenia
  • Painful Joints
  • Periodic Fever Syndromes
  • Periodic Fevers, Aphthous Stomatitis, Pharyngitis, and Adenopathy (PFAPA) Syndrome
  • Rheumatoid Arthritis: How to Treat
  • SAPHO syndrome
  • Schnitzler Syndrome
  • Seronegative Spondyloarthropathies
  • Shoulder Arthritis
  • Spondylitis
  • TNF-Receptor Associated Periodic Syndrome (TRAPS)

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/29/2016, Dr. Kontzias has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English
  • Greek

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