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Alexander Duart Rae-Grant, MD


Alexander Duart Rae-Grant, MD
Department: Mellen Center
Location: Cleveland Clinic Main Campus
Mail Code U10
9500 Euclid Avenue
Cleveland, OH 44195
Alexander Duart Rae-Grant, MD
Department: Neurology
Location: Cleveland Clinic Main Campus
Mail Code U10
9500 Euclid Avenue
Cleveland, OH 44195
Type of Doctor:
Adults Only

Biographical Sketch

Dr. Alex Rae-Grant is a Board Certified Staff Neurologist at the Cleveland Clinic. His areas of expertise are in multiple sclerosis and dementia. He is involved in many educational activities at the Clinic and regionally. He has written a number of text books in neurology and multiple sclerosis.

He joined the staff at the Neurological Institute in 2007 and works at the Mellen Center for MS as well as at the Lou Ruvo Center for Brain Health. At the Mellen Center he directs educational efforts including website management, newly diagnosed classes, regional and national conferences, and patient education material development. He is active in clinical trials in the treatment of MS with the Experimental therapeutics program at the Mellen Center. He also directs the Center for Brain Health at the main Cleveland Clinic campus and is developing clinical trials aimed at early and prodromal Alzheimer's disease at the Mellen Center Campus.

He has written two textbooks of neurology "Neurology for the House Officer" and "Comprehensive Review in Clinical Neurology A Multiple Choice Question Book for the Wards and Boards", and co-edited another textbook of neurology "The 5 minute consult in Neurology". He has co authored a text book on Multiple Sclerosis with Dr. Jeffrey Cohen titled "Handbook of Multiple Sclerosis". He is active in neurology resident education and medical student education and co-directs the neurosciences clerkship at the Cleveland Clinic. He directs a course on critical assessment of the medical literature for the neurology residency at the Cleveland Clinic. In 2009 he was honored as the Teacher of the Year for the neurology program at the Cleveland Clinic. He serves on the Guideline Development Committee of the American Academy of Neurology which develops critical guidelines for patient care in neurology.

He is presently working with a group researching vascular theories of MS using ultrasound, magnetic resonance venography, and pathological anatomy which is supported by the National Multiple Sclerosis society.

Professional Highlights

  • Teacher of the Year Neurology Residency Cleveland Clinic 2009
  • Serves on the Guideline Development Committee of the American Academy of Neurology

Education & Fellowships

Residency - University of Western Ontario, London Health Sciences Centre
London, Ontario Canada
Residency - Sunnybrook Health Science Center
Internal Medicine
North York, Ontario Canada
Internship - Sunnybrook Hospital
Internal Medicine
Ontario Canada
Medical School - McMaster University Faculty of Health Sciences
Hamilton, Ontario Canada
Undergraduate - Yale University
New Haven, CT USA


  • Neurology
  • Royal College of Physicians & Surgeons of Canada

Specialty Interests

multiple sclerosis, Devic's disease, memory impairment, memory loss, mild cognitive impairment, neuroimmunology, neurocognitive disorders including Alzheimer's disease


  • American Academy of Neurology
  • Consortium of Multiple Sclerosis Centers

Treatment & Services

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. The Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, the Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/28/2014, Dr. Rae-Grant has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by the Cleveland Clinic. To learn more about the Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English