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Lyssette Cardona, MD

Lyssette Cardona, MD

Appointed: 2002


Biographical Sketch

Lyssette L. Cardona, MD, MPH, MSHA, AAHIVS,FIDSA has been on Staff in the Department of Infectious Diseases Medicine at Cleveland Clinic Florida in Weston, Fla., since 2002. She was appointed Chairman of the Section of Infectious Diseases in 2006, now Department Chair under the Institute of Medicine. Her specialty interests are in HIV/AIDS,bone-joint infections,mycobacterial infections, travel medicine, general infectious diseases, outpatient antimicrobial therapy, quality in healthcare, women's health and risk management. Dr. Cardona has joint academic appointments as Adjunct Professor at  Barry University in Miami, Fla., and Adjunct Professor in the School of Public Health at Nova Southeastern University,as well as FIU and FAU Schools of Medicine.

Dr. Cardona received her BS in biology from the University of Puerto Rico, Mayaguez, in 1979. She then completed an MPH in epidemiology at Tulane School of Public Health and Tropical Medicine in New Orleans, La. Dr. Cardona earned her medical degree from the University of Puerto Rico Medical School in Rio Piedras in 1983. She completed an internship in internal medicine and residencies in internal medicine and preventive medicine, followed by an infectious disease fellowship, at Tulane University Medical Hospital in New Orleans. Additionally, she completed an MS in health administration at Barry University in Miami, Fla., in 2005. The Infectious Diseases Society inducted Dr. Cardona as a Fellow in 2009.

Her professional experience includes working as Infectious Disease Consultant and Director of AIDS Research Protocols for the Keith Medical Practice Group in Los Angeles, Calif., from 1989 to 1993. She also worked in private practice in internal medicine and infectious disease in Los Angeles during that time. After that, she was Medical Director of the Los Angeles Immune Suppressed/AIDS Unit of the Medical Center of North Hollywood in North Hollywood, Calif (1993-1995). She was Infectious Disease Consultant for the Pacific Oaks Medical Group and Medical Director of the Pacific Oaks Women's Education and Resource Center for HIV in 1994-1995.

From 1995-2002, she served as Infectious Disease Consultant for the Friedberg Medical Group in Ft. Lauderdale, Fla., and Infectious Disease Consultant for Travel Medicine for Weston International Clinic in Weston, Fla. In 2002, she was appointed to Staff in the Department of Infectious Diseases at Cleveland Clinic Florida. Presently, she is Chair of the Department of Infectious Diseases at Cleveland Clinic Florida under the Institute of Medicine.

Dr. Cardona is certified by the American Board of Internal Medicine with subspecialty certification in infectious diseases. She is also certified by the American Academy of HIV Medicine. Dr. Cardona was certified in risk management by the AHCA, Florida, in 2006. She is currently licensed to practice in the state of Florida.

Professional Highlights

AMA CPT E/M Task Force IDSA Representative,2013-4

Broward County Medical Association, Women's Task Force,Co-Chair, 2013-14

Education Committee,Quality Task Force Member, ID Society of America , 2009-present

Clinical Affairs Committee, Member, ID Society of America , 2009-12

HIV/ID MOC Program, Member & Reviewer, ABIM/IDSA , 2010-11,2014

Staph aureus Metrics(SAM) Task Force, ID Society of America, 2012-2014

ID Society of America, Fellow

Department Chair, Infectious Diseases, Cleveland Clinic Florida, 2008–Present

Chair, Infection Control, 2006–2013

Chair, CME Committee, Cleveland Clinic Florida,2010-2014

Co-Chair, CME Committee, Cleveland Clinic Florida, 2005–2010

Employee Health Medical Director, Cleveland Clinic Florida, 2005–2013

Florida Board Member, American Academy HIV Medicine, 2005–2012

Chair,Founding Member, Women's Professional Staff Association,Cleveland Clinic Florida, 2005–2014

Education & Fellowships

Fellowship - Tulane University Hospital & Clinics
Infectious Disease
New Orleans, LA USA
Residency - Tulane University Hospital & Clinics
Internal Medicine
New Orleans, LA USA
Internship - Tulane University Hospital & Clinics
Internal Medicine
New Orleans, LA USA
Medical School - University of Puerto Rico School of Medicine
San Juan Puerto Rico


  • Internal Medicine- Infectious Diseases
  • Internal Medicine

Specialty Interests

HIV/AIDS, bone and joint infections, mycobacterial infections, international travel health, C. difficile, STDs, healthcare and quality in infectious diseases and preventative medicine

Awards & Honors

100 Outstanding Women of Broward County, Honoree, Florida, 2014

Women's Professional Staff Association Achievement Awards,Cleveland Clinic Florida 2007, 2008, 2010, 2012

Castle Connolly List, Top Doctor in South Florida, Infectious Diseases, 2012,2013,2014

Women of Merit, International Business Women Association, Weston, Fla., 2008

Physician of the Year, Cleveland Clinic Florida WPSA, 2007,2012

Certificate of Appreciation, Hospice by the Sea, 2006

Ritter Foundation Merit Scholarships, Barry University, Miami, Fla., 2003–2004

Doctor Congeniality, Cleveland Clinic Hospital, Florida, 2003

Physician of the Month, Cleveland Clinic Hospital, Florida, December 2002

Alpha Omega Alpha Honors Society, Elected 1983

Outstanding Graduate, Medical Class of 1983, Puerto Rico

Tulane Musser-Burch Honor Society, Elected August 1983, New Orleans, La.

Who’s Who of New Orleans, Award of Achievement, 1993

Women of Achievement Award, Tri-Valley Professional Business Clubs, Los Angeles, Calif., 1993

POMG Commendation/AIDS Services Award, Mayor of Los Angeles, 1994

Nuestros Recuerdos, AIDS Community Service Award, 1994

Additional Training

TB/NTM Denver Course, National Jewish Health, 2013

Board-certified, American Academy HIV Medicine, 2005-Present

Florida Risk Management Institute, licensed Risk Manager, AHCA, 2006

International HIV Physician Mentor Certification, 2006

Master's in Health Services Administration, Barry University, Fla., 2005


IDSA, AAHIVS, AMA, Broward County Medical Association, Transplant Society, APIC, SHEA, ASM

Treatment & Services

  • 2nd Opinion Evaluations
  • Clinical Trials
  • Infectious Disease Consultation
  • Infectious Disease Treatment
  • Outpatient Antibiotic Therapy
  • Travel Vaccines

Specialty in Diseases and Conditions

  • AIDS & HIV
  • Bacteremia
  • Bone and Joint Infection
  • Bone Marrow Transplant Related Infections
  • Breast Infections
  • Cardiac Device Infections
  • Cardiac Implantable Electronic Device Infection
  • Cellulitis
  • Chlamydia Trachomatis
  • Defibrillator Infections
  • Encephalitis
  • Endocarditis
  • Fever
  • Fever In Transplant Recipients
  • Fungal Infections
  • General Infectious Diseases
  • General Infectious Transplant
  • General Outpatient Infectious Disease
  • Giardiasis
  • Gonorrhea
  • Herpes
  • Histoplasmosis
  • Infections In Leukemia And Oncology Patients
  • Infective Endocarditis
  • International Travel Related Preparation And Diseases
  • Kidney Infections
  • Meningitis
  • MRSA (Methicillin-resistant Staphylococcus aureus)
  • Mycobacterial Infections
  • Mycobacterium Avium Complex
  • Neurologic Infections
  • Non-Tuberculosis Mycobacteria (ASB)
  • Prosthetic Joint Infections
  • Sepsis
  • Solid Organ Transplant Related Infections
  • Spinal Infections
  • Staphylococcus Aureus Infections
  • Surgical Site and Hospital Acquired Infections
  • Syphilis
  • Transplant Infections
  • Tropical Diseases
  • Tuberculosis
  • Ventricular Shunt Infections

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 5/3/2014, Dr. Cardona has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers’ discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Languages Spoken

  • English
  • Spanish