Department Cardiovascular Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Spanish
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Cardiovascular Medicine
  • Cardiovascular Medicine Department
  • Debridement of Skin and Wound
  • Non-Invasive Diagnostic Testing
  • Non-invasive Testing for Vascular Disease
  • Pseudoaneurysm Injection
  • Sclerotherapy
  • Thrombolytic Therapy
  • Unna Boot Application
  • Vascular Medicine Section
View all 10 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Aortic Aneurysm
  • Adverse Effects Anticoagulants
  • Antiphospholipid Syndrome
  • Aorta Disease
  • Aortic Aneurysms
  • Aortic Occlusion (blockage)
  • Arteriosclerosis Obliterans
  • Atheroembolism
  • Atherosclerosis (vascular)
  • Axillo Subclavian Vein Thrombosis
  • Bleeding Disorders
  • Blood Clots
  • Cardiovascular Risk Prevention
  • Carotid Artery Disease
  • Cellulitis
  • Cerebrovascular Occlusive Disease
  • Chronic Venous Insufficiency (CVI)
  • Coumadin Skin Necrosis
  • Cystic Adventitial Disease
  • Deep Vein Thrombosis
  • Edema
  • Erythema Ab Igne
  • Erythromelalgia
  • External Iliac Artery Endofibrosis
  • Factor V Leiden
  • Fibromuscular Dysplasia (FMD)
  • Frostbite
  • Heparin-induced Thrombocytopenia
  • Hepatic Artery Aneurysm
  • Iliac Artery Occlusion (blockage)
  • Intestinal Ischemic Syndrome
  • Ischemic Digits (Upper Extremity)
  • Klippel-Trenaunay Syndrome (KTS)
  • Leg Circulation Problems
  • Lipedema
  • Lower Extremity Ulcers
  • Lupus Anticoagulant
  • Lymphedema
  • Marfan Syndrome
  • May-Thurner Syndrome (MTS)
  • Median Arcuate Ligament Syndrome
  • Peripheral Artery Disease
  • Popliteal Artery Aneurysms
  • Popliteal Artery Entrapment Syndrome
  • Post-Phlebitic (Thrombotic) Syndrome
  • Protein C and S Deficiencies
  • Prothrombin Gene Mutation
  • Pulmonary Embolism
  • Raynaud's Phenomenon
  • Renal Artery Aneurysm
  • Renovascular Hypertension
  • Restless Leg Syndrome
  • Splenic Artery Aneurysm
  • Stenosis - Spinal
  • Superior Vena Cava Syndrome
  • Swollen Leg
  • Takayasu's Arteritis
  • Thoracic Outlet Syndrome
  • Thromboangitis Obliterans
  • Ulnar Artery Aneurysm
  • Varicose Veins
  • Vascular Anomalies
  • Vascular Diseases
  • Venous Insufficiency
  • Venous Stasis Leg Ulcers
  • Visceral Artery Aneurysms
  • Visceral Ischemic Syndrome
View all 67 Specialties +


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About John Bartholomew, MD

John R. Bartholomew, MD, is Director of the Thrombosis Center and a staff physician in the Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute at Cleveland Clinic. He has a joint appointment to the Department of Hematology/Oncology. Dr. Bartholomew is board-certified as a Diplomat of the American Board of Internal Medicine and the American Board of Vascular Medicine. He is a Professor of Medicine for the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.

Specialty/Clinical interests: New oral anticoagulants, adverse effects of anticoagulants, heparin-induced thrombocytopenia, blood clots, hypercoagulable states (thrombophilia), deep vein thrombosis (DVT), pulmonary embolism, thrombosis in unusual locations, inferior vena cava filters, general vascular medicine, peripheral arterial disease, unusual vascular disorders including erythromelalgia, pernio, lymphedema and lipedema.

Number of Procedures Performed:  Throughout his career, Dr. Bartholomew has performed more than 20,000 sclerotherapy procedures for patients with varicose and spider veins.

Success Rates: The Section of Vascular Medicine at Cleveland Clinic is one of the most active Vascular Medicine programs in the United States. Our specialists treat patients with a wide variety of vascular problems, including all forms of arterial, venous, and lymphatic disorders, cardiovascular risk factor management, thrombotic disorders, hypercoagulable states and wound care. In addition, we have expertise on the use of the new oral anticoagulants. Cleveland Clinic has specialty clinics for patients with a number of disorders, including fibromuscular dysplasia, retrieval of Inferior vena cava filters, endovenous laser ablation (first nationally accredited academic practice), and lymphedema. Patients also benefit from programs designed as a result of the department’s close collaborations with Medical Genetics, Pulmonary Function lab and Physical Therapy. Success rates for specific procedures are available at

Education and Training: Dr. Bartholomew completed his undergraduate work at Central Michigan University, and received his medical degree from the Autonomous Universidad De Guadalajara, in Guadalajara, Jalisco, Mexico. He completed his internship and residency at Maryland General Hospital in Baltimore, where he was Chief Resident. Dr. Bartholomew was awarded a fellowship by the Johns Hopkins Hospital and appointed Senior Clinical Fellow in the Division of Hematology. While at Johns Hopkins, he received the William Bell Award for Patient Care.

Prior to joining the Cleveland Clinic in 1988, Dr. Bartholomew was the Assistant Director of Internal Medicine Education at St. Joseph Hospital at Michigan State University, where he was given the Instructor of the Year Award for the Family Practice Residency Program. He also served as Director of the Eastern Michigan Hemophilia Center.

Dr. Bartholomew is the Director of the Vascular Medicine Section’s anticoagulation clinic. In 2003, Dr. Bartholomew was part of the clinical faculty for the Joint Commission Resources, Inc., for the Joint Commission on Accreditation of Hospital Organizations (JCAHO). He has also been a member of the Deep Vein Thrombosis Steering Committee for the National Quality Forum, which sets the national standards for the care of patients with Deep Vein Thrombosis and Pulmonary Embolism. He currently serves as the Director of the Cleveland Clinic Health Systems efforts to prevent and treat deep vein thrombosis and pulmonary embolism. He has a joint clinic with Interventional Radiology to evaluate patients for retrieval of their inferior vena cava filters and is Co-Director of the Pulmonary Embolism Response Team.

Research, Publications and Speaking: Dr. Bartholomew has published numerous articles and abstracts in professional scientific journals, including the Annals of Internal Medicine, Journal of Thrombosis and Hemostasis, Journal of Thrombosis and Thrombolysis, Transfusion, Cardiovascular Surgery, Circulation, the Cleveland Clinic Journal of Medicine, Chest, Archives of Internal Medicine, American Journal of Cardiology, Journal of American College of Cardiology, Journal of Pediatrics, Vascular and Endovascular Surgery, and Vascular Medicine. His publications focus on topics related to smokeless tobacco and cardiovascular risk, peripheral artery disease, pulmonary embolism, and heparin-induced thrombocytopenia, and deep vein thrombosis, among others. He has written more than 45 chapters in medical textbooks related to atheromatous embolization, stasis leg ulcers, hypercoagulable states, heparin-induced thrombocytopenia, and peripheral arterial disease.

Dr. Bartholomew has spoken at many major national meetings, workshops, symposiums and conferences about the diagnosis and treatment of patients with deep vein and pulmonary embolism and peripheral arterial disease, and the diagnosis and management of patients with hypercoagulable states and heparin-induced thrombocytopenia, as well as patients with unusual vascular disorders and lymphedema and lipedema.

About Dr. Bartholomew: “I enjoy my field because many of the patients I treat have disorders that are not well known to other physicians. In that way, patients are extremely thankful that there are physicians that deal with these unusual and often complicated diseases. Many of our patients go from doctor to doctor before they find the right answer to their medical problems, and it is gratifying to let them know that someone understands what is wrong with them. In addition, I like the opportunity to use the newer anticoagulants to treat patients who have blood clots and to help advance the field of medicine related to those events.”

Leisure Activities: In his spare time, Dr. Bartholomew enjoys fishing, hiking, skiing, writing and reading.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Johns Hopkins Hospital
Baltimore, MD USA

Residency - Maryland General Hospital
Internal Medicine
Baltimore, MD USA

Internship - Maryland General Hospital
Fifth Pathway
Baltimore, MD USA

Medical Education - Universidad Autonoma De Guadalajara
Guadalajara, Jalisco, Mexico

Undergraduate - Central Michigan University
Mt. Pleasant, MI USA


  • Internal Medicine

Specialty Interests

New oral anticoagulants, adverse effects of anticoagulants, heparin-induced thrombocytopenia, blood clots, hypercoagulable states (thrombophilia), deep vein thrombosis (DVT), pulmonary embolism, thrombosis in unusual locations, inferior vena cava filters, general vascular medicine, peripheral arterial disease, unusual vascular disorders including erythromelalgia, pernio, lymphedema and lipedema

Awards & Honors

  • 2014 Regional Top Doctor, Castle Connolly
  • Cleveland’s Best Doctors, Cleveland Magazine
  • Teacher of the Year, Cleveland Clinic Department of Vascular Medicine
Research & Publications

Research & Publications

See publications for John Bartholomew, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/9/2020, Dr. Bartholomew has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

197 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 5

74 Patient Comments

Reviewed on Oct 2, 2020

the doctor was excellent!

Reviewed on Sep 28, 2020

I appreciate the ease and thoroughness in being abl to discuss my condition with Dr. Bartholomew..

Reviewed on Sep 28, 2020

Of course video contact is not as optimal as in person visit, but provides a valuable experience for me to stay in contact with my Cleveland Clinic provider.

Reviewed on Sep 28, 2020

Dr B is the definition of physician. He is amazing

Reviewed on Sep 21, 2020

I have the utmost confidence in Dr. Bartholomew. I would travel anywhere to continue treatment with him. He is a great communicator, concerned about my progress and positive in his comments and direction. He offered me treatment options and did not pigeon-hole me in one plan.

Reviewed on Sep 11, 2020

always a great experience with Dr Bartholamew

Reviewed on Sep 10, 2020

very pleased over all experience with doctor Bartholomew and office team.

Reviewed on Sep 8, 2020

Dr Bartholomew provides excellent personal care. Very thorough, listens and asks questions. Best Dr and best facility I have ever visited. Everyone I come in contact with is friendly, polite, on time and respectful.

Reviewed on Sep 2, 2020

Dr. Bartholomew is an excellent doctor . I would recommend him to anyone.

Reviewed on Sep 2, 2020

I could not have been happier with the appointment that I had with Dr. Bartholomew. I scheduled the appointment to address a number of issues including a pre-existing condition that I had been seen at the clinic for previously (my past physician had left the clinic). He spent time on all of the issues and provided a complete physical exam and conversation to address them. He was thorough in addressing and listening to my questions and concerns and provided needed tests and materials that assisted me in understanding all of the issues. Following the appointment, he followed up to make sure I understood the treatment, tests and further recommendations for the conditions we discussed. His kindness, professional manner and sense of humor made what can be a stressful situation, much more relaxing.

Reviewed on Aug 26, 2020

Dr. B. was very good and caring. he discovered blood clots in my wife's leg. started immediately treatment. He was very busy and was rushed but I think he did the best he could under the circumstances. He did not have time to address all my wife's issues in this visit.

Reviewed on Aug 26, 2020

Dr. Bartholomew was exceptionally kind, patient and took a lot of time with me. he and his staff are amazing.

Reviewed on Aug 26, 2020

Dr. Bartholomew is amazing!

Reviewed on Aug 26, 2020

Dr. Bartholomew and his team are just incredible. They are so kind and patient with me. Dr. Bartholomew takes his time with me, let's me ask as many questions as I need, and never rushes me. I know how busy he must be, and I am so impressed with the time and attention he provides. It is an exceptional level of care. I am also so impressed with how the entire department runs. Communication is prompt and clear, wait times are almost non-existent, and every person you encounter is respectful and kind. It makes such a difference especially when you are nervous/anxious for the appointment.

Reviewed on Aug 26, 2020

Please see previous response. I can't say enough good things about Dr. Bartholomew and his staff!

Reviewed on Aug 26, 2020

I had a great experience at Cleveland Clinic and with Dr. Bartholomew and his team. I would highly recommend to anyone.

Reviewed on Aug 12, 2020

I love that doctor Bartholomew is very open and thorough

Reviewed on Aug 5, 2020

Dr. Bartholomew and his Team are awesome!

Reviewed on Aug 3, 2020

we love Dr Barthalowmew and his staff and ALWAYS HAVE A VERY GREAT EXPERIENCE!

Reviewed on Aug 3, 2020

Dr. Bartholomew was very thorough in discussing options for my Reynaud's.

Reviewed on Jul 28, 2020

The office staff was very kind. Dr. Bartholomew did not make me feel rushed at all. He seemed to have a genuine concern for my current condition. He provided me with a folder of information that included education. very much appreciated. He was a very kind man with wonderful bed side manner!

Reviewed on Jul 27, 2020

Dr. Bartholomew was outstanding in all respects.

Reviewed on Jul 21, 2020

I live in Indianapolis and drive to Cleveland for my appointments. The doctor and staff are always very helpful in coordinating my tests and doctor's visits so I can complete everything the same day and early enough in the day should anything else arise such as lab work for any studies I participate in.

Reviewed on Jul 14, 2020

CC changing the doctor experience. much appreciated. gone are the waiting lines ...

Reviewed on Jul 14, 2020

dr bartholomew is retiring. his approach is worth emulating by his replacement

Reviewed on Jul 13, 2020

Dr. Bartholomew is hands down one of the best physicians I have ever had

Reviewed on Jul 1, 2020

I would recommend Dr. Bartholomew to anyone....kindest and most professional doctor ever!

Reviewed on Jul 1, 2020

my appointment with Dr. Bartholomew was wonderful and he is very knowledgeable with lymphedema and was very supportive in providing me with the proper information and did a very thorough exam. Also gave me information to educate myself to slow the growth of my condition.

Reviewed on Jun 29, 2020

Even if I have to wait weeks, Dr. Bartholomew is worth waiting for..

Reviewed on Jun 29, 2020

Dr. B is one of the best physicians at the Clinic. He is thorough and reviews our cases and knows our history. We have been with him for 16 years.

Reviewed on Jun 22, 2020

Dr B has always been a pleasure to work with

Reviewed on Jun 19, 2020

Dr. Bartholomew answered all of my questions completely, explained the purpose of tests and did a good exam of leg circulation.

Reviewed on Jun 18, 2020

Dr Bartholomew is one of the most patient centric clinicians I've ever known. He deals in reality with the most phenomenal level of patient care and concern.

Reviewed on Jun 15, 2020

I have most utmost respect and confidence in Dr. Bartholomew and the staff.

Reviewed on Jun 15, 2020

just a wonderful caring and through

Reviewed on Jun 9, 2020

I have always had good visits with Dr. Bartholomew. He is kind and caring. Also, I brought up a procedure that he said he hadn't heard of before, but while we were talking, he looked it up on the computer and remembered being at a seminar where it was discussed. He also said he would check with the surgeons to see if they performed it.

Reviewed on Jun 3, 2020

wonderful meeting Dr. Bartholomew. I had a great level of comfort discussing my medical conditions with him. Excellent professional that I have recommended to several friends. His demeanor made me feel very comfortable during my visit.

Reviewed on Jun 3, 2020

I live 35 minutes from Pittsburgh and yet it is my choice to seek treatment from physicians that provide a level of comfort.

Reviewed on May 27, 2020

Dr. Bartholomew is simply the best. I am so very grateful for his care and advice.

Reviewed on May 22, 2020

He is a fabulous doctor. We need more like him.

Reviewed on May 22, 2020

doctor was extremely thorough and professional

Reviewed on May 20, 2020

dr Bartholomew is the best! He listens and truly helps you with your problems!

Reviewed on May 13, 2020

Dr. Bartholomew is one of the best doctors I've ever had

Reviewed on Apr 27, 2020

Dr. Bartholomew is a very caring and interested physician. He asks very good qustions and takes notes to follow up as needed.

Reviewed on Apr 27, 2020

Dr. Barholomew took notes and will refer to the appropriates specialists.

Reviewed on Apr 20, 2020

Dr. Barthalamew was amazing! He was very thorough and explained everything very well. he took his time with my daughter and explained everything he was doing and why.

Reviewed on Mar 18, 2020

no complaints about Dr. John Bartholomew or his staff. Dr. B and his RN is kind, friendly and respectful.

Reviewed on Mar 16, 2020

confidence in doctor, encouraging, informative

Reviewed on Feb 26, 2020

a fantastic Dr and Laura his nurse is incredible

Reviewed on Feb 18, 2020

My experience from valet parking to having the red coat girl push me in a wheelchair to the people behind the desk to Dr B's nurse practitioner to Dr Bartholomew I was treated with respect and kindness from everyone.

Reviewed on Feb 18, 2020

excellent experience Dr Barthalomew squeezed me in on a same day appointment during his lunch break. He is an exceptional doctor and human being. He took wonderful care of my father and now cares for me. An outstanding physician and compassionate individual always putting his patients first.

Reviewed on Feb 3, 2020

Treatment was good and kind from the doctor and nurses.

Reviewed on Jan 29, 2020

Cleveland Clinic is an amazing place. doctor Bartholomew was outstanding in his knowledge of my case.

Reviewed on Jan 29, 2020

Dr. Bartholomew is very thorough and informative. After seeing over 20 specialists, he is the only one that could and did help me.

Reviewed on Jan 15, 2020

dr b seems like an old friend who is interested in you as a person

Reviewed on Jan 14, 2020

Dr. Bartholomew was thorough in his examination and discussion of possible courses of treatment. I feel confident in his assessment of my condition interpretation of tests that were performed. I have complete confidence in Dr. Bartholomew.

Reviewed on Jan 13, 2020

Dr. Bartholomew is an awesome provider. I was really surprised during this visit how rushed I felt. Usually he is not like this. I know he was under a lot of pressure in this day. I hope he gets an opportunity to have some lighter days soon. I still love & respect him as my provider. He is awesome

Reviewed on Jan 13, 2020

when I read Dr. Bartholomew's biography on the Cleveland Clinic, I knew he was the person I wanted to see. I had in a previous job sponsored research physicians to present at grand rounds at the teaching hospitals where I am from. You soon become familiar with those who not only are excellent in their specialty, but who are also able to relate well with patients. I felt that was the kind of doctor Dr. Bartholomew was and I was not disappointed. His human relations skills were as impressive as his medical knowledge of my disorder.

Reviewed on Jan 13, 2020

Dr. Bartholomew is an amazing doctor. I have CRPS and Erythromelalgia. he takes time to listen to everything I tell him. I take photos of my condition at it's worse days or when something wierd happens. This time it just so happens, that I occasionally have blood vessels burst and I had taken some pictures. He knew right away what it was. He said it is rare and I'm probably the 1st person diagnosed with a that has Erythromelalgia. most people have fibromyalgia there are about 24 people with it. so, my stress level with my health issue are very high. but, having a doctor that is so understanding. Helps so much. Thank you

Reviewed on Jan 10, 2020

Dr. Bartholomew is very dedicated. He explains what he is doing and asks if I ok. He is humorous, pleasant, respectful and of course knowledgeable.

Reviewed on Dec 27, 2019

Dr John and his staff are all very good. One of the few doctors I trust completely

Reviewed on Dec 24, 2019

smart and detailed physician who was looking to help

Reviewed on Dec 23, 2019

very good doctor and knowledgeable

Reviewed on Dec 23, 2019

would refer any of my family to doctor

Reviewed on Dec 11, 2019

dr John was very thorough and a good communicator

Reviewed on Dec 10, 2019

I am so glad I visited Cleveland clinic and the stuff are so kind and helpful and Doctor John answered all the questions I had and I am so concerned about my health and finally I am being referred to a specialist for a second opinion about lymphadema and the news was heart broken that there no cure for it just there is treatments and surgery and God will take care of the rest.Thank you Cleveland clinic and Doctor John and staff,Merry Christmas to all.

Reviewed on Dec 10, 2019

dr. bartholomew is an amazing physician. the time he spends is above and beyond. his compassion shows.

Reviewed on Dec 10, 2019

I can't say enough about dr bartholomew, he is an exceptional physician!

Reviewed on Dec 3, 2019

very empathic staff and Doctor

Reviewed on Dec 3, 2019

For the first time in a long time I was actually listened to and heard about this issues that bought me to the appointment. I wasn't rushed and I left feeling that my provider provided the proper course of action for my condition as well as going the extra mile to provide me with some awsome literature concerning my condition

Reviewed on Dec 2, 2019

Dr. Bartholomew is a very caring individual. He is courteous and tries to fully explain your condition and treatment for it accordingly.

Reviewed on Nov 26, 2019

Doctor Bartholomew is an excellent caregiver and showed compassion and kindness towards me as this is my first experience at Vascular medicine. I'm not quite sure what is next besides cutting out all night shade Foods.

Reviewed on Nov 25, 2019

Dr Bartholomew was extremely professional and thorough. It was an excellent appointment in every way.

Reviewed on Nov 20, 2019

Dr Bartholomew took excellent care of my person. A sonagram was ordered to determine if I should continue Eliquis. 1 less drug I take. His personality is Awesome. Please take care and Appreciate him more. Thanks

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