Department Vascular Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Spanish
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Cardiovascular Medicine Department
  • Debridement of Skin and Wound
  • Non-Invasive Diagnostic Testing
  • Non-invasive Testing for Vascular Disease
  • Pseudoaneurysm Injection
  • Sclerotherapy
  • Thrombolytic Therapy
  • Unna Boot Application
  • Vascular Medicine Section
View all 9 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Aortic Aneurysm
  • Adverse Effects Anticoagulants
  • Antiphospholipid Syndrome
  • Aorta Disease
  • Aortic Aneurysms
  • Aortic Occlusion (blockage)
  • Arteriosclerosis Obliterans
  • Atheroembolism
  • Atherosclerosis (vascular)
  • Axillo Subclavian Vein Thrombosis
  • Bleeding Disorders
  • Blood Clots
  • Cardiovascular Risk Prevention
  • Carotid Artery Disease
  • Cellulitis
  • Cerebrovascular Occlusive Disease
  • Chronic Venous Insufficiency (CVI)
  • Coumadin Skin Necrosis
  • Cystic Adventitial Disease
  • Deep Vein Thrombosis
  • Edema
  • Erythema Ab Igne
  • Erythromelalgia
  • External Iliac Artery Endofibrosis
  • Factor V Leiden
  • Fibromuscular Dysplasia (FMD)
  • Frostbite
  • Heparin-induced Thrombocytopenia
  • Hepatic Artery Aneurysm
  • Iliac Artery Occlusion (blockage)
  • Intestinal Ischemic Syndrome
  • Ischemic Digits (Upper Extremity)
  • Klippel-Trenaunay Syndrome (KTS)
  • Leg Circulation Problems
  • Lipedema
  • Lower Extremity Ulcers
  • Lupus Anticoagulant
  • Lymphedema
  • Marfan Syndrome
  • May-Thurner Syndrome (MTS)
  • Median Arcuate Ligament Syndrome
  • Peripheral Artery Disease
  • Popliteal Artery Aneurysms
  • Popliteal Artery Entrapment Syndrome
  • Post-Phlebitic (Thrombotic) Syndrome
  • Protein C and S Deficiencies
  • Prothrombin Gene Mutation
  • Pulmonary Embolism
  • Raynaud's Phenomenon
  • Renal Artery Aneurysm
  • Renovascular Hypertension
  • Restless Leg Syndrome
  • Splenic Artery Aneurysm
  • Stenosis - Spinal
  • Superior Vena Cava Syndrome
  • Swollen Leg
  • Takayasu's Arteritis
  • Thoracic Outlet Syndrome
  • Thromboangitis Obliterans
  • Ulnar Artery Aneurysm
  • Varicose Veins
  • Vascular Anomalies
  • Vascular Diseases
  • Venous Insufficiency
  • Venous Stasis Leg Ulcers
  • Visceral Artery Aneurysms
  • Visceral Ischemic Syndrome
View all 67 Specialties +


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About John Bartholomew, MD

John R. Bartholomew, MD, is Director of the Thrombosis Center and a staff physician in the Sydell and Arnold Miller Family Heart & Vascular Institute at Cleveland Clinic. He has a joint appointment to the Department of Hematology/Oncology. Dr. Bartholomew is board-certified as a Diplomat of the American Board of Internal Medicine and the American Board of Vascular Medicine. He is a Professor of Medicine for the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.

Specialty/Clinical interests: New oral anticoagulants, adverse effects of anticoagulants, heparin-induced thrombocytopenia, blood clots, hypercoagulable states (thrombophilia), deep vein thrombosis (DVT), pulmonary embolism, thrombosis in unusual locations, inferior vena cava filters, general vascular medicine, peripheral arterial disease, unusual vascular disorders including erythromelalgia, pernio, lymphedema and lipedema.

Number of Procedures Performed:  Throughout his career, Dr. Bartholomew has performed more than 20,000 sclerotherapy procedures for patients with varicose and spider veins.

Success Rates: The Section of Vascular Medicine at Cleveland Clinic is one of the most active Vascular Medicine programs in the United States. Our specialists treat patients with a wide variety of vascular problems, including all forms of arterial, venous, and lymphatic disorders, cardiovascular risk factor management, thrombotic disorders, hypercoagulable states and wound care. In addition, we have expertise on the use of the new oral anticoagulants. Cleveland Clinic has specialty clinics for patients with a number of disorders, including fibromuscular dysplasia, retrieval of Inferior vena cava filters, endovenous laser ablation (first nationally accredited academic practice), and lymphedema. Patients also benefit from programs designed as a result of the department’s close collaborations with Medical Genetics, Pulmonary Function lab and Physical Therapy. Success rates for specific procedures are available at

Education and Training: Dr. Bartholomew completed his undergraduate work at Central Michigan University, and received his medical degree from the Autonomous Universidad De Guadalajara, in Guadalajara, Jalisco, Mexico. He completed his internship and residency at Maryland General Hospital in Baltimore, where he was Chief Resident. Dr. Bartholomew was awarded a fellowship by the Johns Hopkins Hospital and appointed Senior Clinical Fellow in the Division of Hematology. While at Johns Hopkins, he received the William Bell Award for Patient Care.

Prior to joining the Cleveland Clinic in 1988, Dr. Bartholomew was the Assistant Director of Internal Medicine Education at St. Joseph Hospital at Michigan State University, where he was given the Instructor of the Year Award for the Family Practice Residency Program. He also served as Director of the Eastern Michigan Hemophilia Center.

Dr. Bartholomew is the Director of the Vascular Medicine Section’s anticoagulation clinic. In 2003, Dr. Bartholomew was part of the clinical faculty for the Joint Commission Resources, Inc., for the Joint Commission on Accreditation of Hospital Organizations (JCAHO). He has also been a member of the Deep Vein Thrombosis Steering Committee for the National Quality Forum, which sets the national standards for the care of patients with Deep Vein Thrombosis and Pulmonary Embolism. He currently serves as the Director of the Cleveland Clinic Health Systems efforts to prevent and treat deep vein thrombosis and pulmonary embolism. He has a joint clinic with Interventional Radiology to evaluate patients for retrieval of their inferior vena cava filters and is Co-Director of the Pulmonary Embolism Response Team.

Research, Publications and Speaking: Dr. Bartholomew has published numerous articles and abstracts in professional scientific journals, including the Annals of Internal Medicine, Journal of Thrombosis and Hemostasis, Journal of Thrombosis and Thrombolysis, Transfusion, Cardiovascular Surgery, Circulation, the Cleveland Clinic Journal of Medicine, Chest, Archives of Internal Medicine, American Journal of Cardiology, Journal of American College of Cardiology, Journal of Pediatrics, Vascular and Endovascular Surgery, and Vascular Medicine. His publications focus on topics related to smokeless tobacco and cardiovascular risk, peripheral artery disease, pulmonary embolism, and heparin-induced thrombocytopenia, and deep vein thrombosis, among others. He has written more than 45 chapters in medical textbooks related to atheromatous embolization, stasis leg ulcers, hypercoagulable states, heparin-induced thrombocytopenia, and peripheral arterial disease.

Dr. Bartholomew has spoken at many major national meetings, workshops, symposiums and conferences about the diagnosis and treatment of patients with deep vein and pulmonary embolism and peripheral arterial disease, and the diagnosis and management of patients with hypercoagulable states and heparin-induced thrombocytopenia, as well as patients with unusual vascular disorders and lymphedema and lipedema.

About Dr. Bartholomew: “I enjoy my field because many of the patients I treat have disorders that are not well known to other physicians. In that way, patients are extremely thankful that there are physicians that deal with these unusual and often complicated diseases. Many of our patients go from doctor to doctor before they find the right answer to their medical problems, and it is gratifying to let them know that someone understands what is wrong with them. In addition, I like the opportunity to use the newer anticoagulants to treat patients who have blood clots and to help advance the field of medicine related to those events.”

Leisure Activities: In his spare time, Dr. Bartholomew enjoys fishing, hiking, skiing, writing and reading.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Johns Hopkins Hospital
Baltimore, MD USA

Residency - Maryland General Hospital
Internal Medicine
Baltimore, MD USA

Internship - Maryland General Hospital
Fifth Pathway
Baltimore, MD USA

Medical Education - Universidad Autonoma De Guadalajara
Guadalajara, Jalisco, New Mexico

Undergraduate - Central Michigan University
Mt. Pleasant, MI USA


  • Internal Medicine

Specialty Interests

New oral anticoagulants, adverse effects of anticoagulants, heparin-induced thrombocytopenia, blood clots, hypercoagulable states (thrombophilia), deep vein thrombosis (DVT), pulmonary embolism, thrombosis in unusual locations, inferior vena cava filters, general vascular medicine, peripheral arterial disease, unusual vascular disorders including erythromelalgia, pernio, lymphedema and lipedema

Awards & Honors

  • 2014 Regional Top Doctor, Castle Connolly
  • Cleveland’s Best Doctors, Cleveland Magazine
  • Teacher of the Year, Cleveland Clinic Department of Vascular Medicine
Research & Publications

Research & Publications

See publications for John Bartholomew, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/4/2019, Dr. Bartholomew has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Royalty Payments. Dr. Bartholomew receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • Cleveland Clinic Foundation

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

217 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.9
Courtesy, Respect & Concern 4.9
Knows Medical History 4.7
Time Spent with Patient 4.9
Patient Rating of Doctor 4.9

46 Patient Comments

Reviewed on Aug 26, 2019

he upset me. He was too direct and kind of scary. it would have been nice if you had a female Doctor. I feel their easier to talk to. I had hard time answering his questions it felt like badgering. I was scared after talking to him all I wants was sailean in my bulging leg vein now I am signed up for exploring of my leg vein to see if I am a candidate for vein surgery.this test or wear support hose for the rest of your life Yuck. I was not prepared for this outcome

Reviewed on Aug 21, 2019

Good, Dr. Bartholomew is very caring and kind and spends time listening to you. I have recommended him to many people that have gone to him.

Reviewed on Aug 19, 2019

as always Dr. Bartholomew goes above & beyond to answer questions & give patient 100% of his attention.

Reviewed on Aug 14, 2019

Dr. Bartholomew is FANTASTIC and truly cares about me as his patient.

Reviewed on Aug 9, 2019

Dr. Bartholomew is one of the most kind, understanding and compassionate physicians I have ever met.

Reviewed on Jul 31, 2019

Dr B was excellent! we definitely felt like the 7 hour drive was worth it, he explained our daughters genetic condition to us in ways that was understandable and also spoke directly to her and she loved his sense of humor

Reviewed on Jul 11, 2019

Dr. Bartholomew listened carefully to both my wife and me and answered all of both of our questions patiently. I give him the highest grade.

Reviewed on Jul 8, 2019

Dr. Bartholomew is an outstanding, knowledgeable doctor.

Reviewed on Jul 5, 2019

seldom can one schedule an appt at my location in Strongsville--usually have to go 25 to 50 miles away if you aren't already connected to a physician in Strongsville. It is the same with with tests. you can't get anything done with the clinic in less than 30 days and it is usually closer to 60 days. when you are already working with a physician, things usually work a little better. the clinic scheduling system is pretty much a total disaster. I have never run into anyone who would disagree and I have talked with a good many people.

Reviewed on Jul 5, 2019

Dr Bartholomew is outstanding!!!

Reviewed on Jun 14, 2019

Dr. Bartholomew is an excellent Dr., he is very thorough and he is pretty prompt on your appointment time. I prefer the Strongsville Clinic as opposed to the main campus.

Reviewed on Jun 14, 2019

We thoroughly enjoyed Doctor Bartholomew. A real genuine doctor that gives you a thorough explanation and cares about you as a patient.

Reviewed on Jun 7, 2019

Dr. Bartholomew was extremely knowledgeable, easy to understand, and provided excellent care to my Mom.

Reviewed on Jun 6, 2019

I was late to my apt because I was in the wrong waiting room. I was still seen by the Doctor even though I was a complicated case and I interrupted his schedule. I appreciate everyone trying to work with me and not making me feel bad for being late due to I was in the wrong waiting room.

Reviewed on May 24, 2019

Dr Bartholomew is very caring and considerate of your problem

Reviewed on May 24, 2019

The world needs more doctors like him!

Reviewed on May 20, 2019

Dr. Bsrtholomew find the balance between being an exceptional medical provider and extending care and compassion. I drive quite a distance to see him, and it's worth it. I know he continues to take exceptional care of me and I am confident his treatment plan is the best one for me.

Reviewed on May 14, 2019

Dr Bartholomew is wonderful and knowledgeable and has great people skills

Reviewed on May 3, 2019

Excellent doctor. Kind, courteous, very professional. Actually talked to me, answered my questions. Thorough exam with explanations as it progressed. Took the time to answer my questions. I received a thorough "visit summary" that covered everything we discussed. Above and beyond my usual experiences with other clinic visits I've had in recent past. Dr. Bartholomew is a 5- star Doctor!!

Reviewed on Apr 23, 2019

Dr. Bartholomew is always personable and patient, listening to my concerns and taking care of me.

Reviewed on Apr 17, 2019

Very pleased with the doctor and the staff

Reviewed on Apr 16, 2019

excellent doctor. been with him over 20 years. Trust him and implicitly

Reviewed on Apr 16, 2019

Dr.B had very pointed questions and got to the heart of the matter.

Reviewed on Apr 10, 2019

I look forward to my appointments with Dr. John. He is very knowledgeable, informative, and caring.

Reviewed on Apr 4, 2019

dr Bartholomew is the best dr and human being!!!

Reviewed on Mar 15, 2019

One of the nicest doctors I've met. He instilled a lot of confidence in me about having my procedure done.

Reviewed on Mar 6, 2019

Dr. Bartholomew was very nice supportive and spent quality time addressing my concerns

Reviewed on Mar 5, 2019

i liked laura and dr. Bartholomew and there team

Reviewed on Mar 4, 2019

Excellent experience! Love Dr. Bartholomew!

Reviewed on Feb 20, 2019

dr. Bartholomew was exactly on time, courteous and extremely knowledgeable about my condition. He spent a long time with me going over the situation and I was extremely happy with my care

Reviewed on Feb 18, 2019

Dr. Bartholomew is very knowledgeable, professional, and caring. I am very confident in his care.

Reviewed on Feb 18, 2019

Dr. Bartholomew was wonderful....very thorough, respectful and my concerns were addressed.

Reviewed on Feb 11, 2019

Dr. Bartolomew was extemely professional, yet affable. He was very thoughtful in his approach of analyzing potential issues. I felt as though I was his only patient for the day. One of the best physicians I've ever encountered. Period. First class.

Reviewed on Feb 5, 2019

Most impressive was Dr Bartholomew escorted me to my next appointment. Never felt like anyone was rushing through my appointment. Felt genuinely listened to.

Reviewed on Feb 4, 2019

I think Dr. Bartholomew is excellent. I can't think of another doctor who provides better explanations, or tries to help a patient understand, than he does.

Reviewed on Jan 25, 2019

Dr. Bartholomew had reviewed my medical history and was totally up to date before I saw him for my visit. He asked pointed questions, explained everything to me satisfactorily and performed a very thorough examination. He referred me to have blood tests and a urinalysis and got back to me to explain the results as soon as he received them. I would recommend him, without reservation.

Reviewed on Jan 21, 2019

Dr Bartholomew and his nurse, Laura Brees were excellent in making my 2nd opinion at Cleveland Clinic very relaxing and comforting. At the time of the visit, Cleveland was experiencing a hugh snow storm and coming from Pennsylvania, the two of them made the trip worthwhile. Thank you for maintaining an excellent clinic and hope it continues to be such in the future

Reviewed on Jan 15, 2019

professional. caring very good experience : the doctor explains everything and has the expertise and experience to give me the the best care which is why I travel to Cleveland .

Reviewed on Jan 14, 2019

Dr. B came highly recommended by my PCP; several of the staff commented Dr B was the 'best' in the department; he exceeded my expectations.

Reviewed on Jan 11, 2019

One of the best visits I have had with a doctor. All of the above items he exceeded expectations. Very impressed.

Reviewed on Jan 8, 2019

The Staff was excellent from the scheduling of the appointment up to and including the examination. Dr. Bartholomew was very thorough with my exam and had reviewed my file before the appointment. He was very knowledgeable of my condition and previous treatment. Excellent patient care and medical expertise.

Reviewed on Oct 18, 2018

I really appreciated it that Dr. Bartolomew sent a letter, along with all test results, clearly explaining his analysis of my condition and his recommendations for the future. That is very valuable, I loved receiving it. It makes certain that I clearly understand his opinion and can accurately share his analysis with my other doctors.

Reviewed on Sep 28, 2018

Dr Bartholemew is the best doctor in the state. bar none

Reviewed on Sep 26, 2018

Provider was sarcasticsarcasm. Thought he knew everything. Made a comment "you know your not the only patient we have today". Bad experience with provider and first time at main campus. He did not want to take the extra time.

Reviewed on Sep 25, 2018

he was kind enough to get me to a GI consultation right after our appointment. GI doctor didn't explain or listen well.

Reviewed on Sep 18, 2018

I don't usually take the time to complete these type of surveys, but that was by far the best experience I've had at the Clinic (or at any doctor's office for that matter). The staff was very courteous and the provider was extremely knowledgeable and helpful in diagnosing/resolving my health issues. Also took the time to explain what was happening in terms that I can actually understand.

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