Department Mellen Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Consultation and Long-term Care
  • Lumbar Puncture (Spinal Tap)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Autoimmune Encephalitis
  • Devic's Disease (Neuromyelitis Optica)
  • Multiple Sclerosis
  • Neuroimmunology
  • Optic Neuritis
  • Transverse Myelitis
View all 6 Specialties +


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About Alexander Duart Rae-Grant, MD

Dr. Alex Rae-Grant is a Board Certified Staff Neurologist at the Cleveland Clinic. He is a Professor of Medicine (Neurology) at the Cleveland Clinic Lerner College of Medicine. His area of expertise is in multiple sclerosis and related disorders. He is involved in many educational activities at the Clinic and regionally. He has written a number of text books in neurology and multiple sclerosis.

He joined the staff at the Neurological Institute in 2007 and works at the Mellen Center for MS. At the Mellen Center he directs educational efforts including website management, regional and national conferences, and patient education material development. He is active in clinical trials in the treatment of MS with the Experimental therapeutics program at the Mellen Center. He is also the director of the Center for Continuing Education for the Cleveland Clinic.

He has written three textbooks of neurology: "Ultimate review in Neurology",  "Neurology for the House Officer" and "Comprehensive Review in Clinical Neurology A Multiple Choice Question Book for the Wards and Boards", and co-edited another textbook of neurology "The 5 minute consult in Neurology". He has co authored a text book on Multiple Sclerosis with Dr. Jeffrey Cohen titled "Handbook of Multiple Sclerosis" and coedited another textbook with Dr. Robert Fox and Dr. Francois Bethoux entitled "Multiple sclerosis and related disorders". He is active in neurology resident education and medical student education.  He serves on the Guideline Development, Dissemination and Implementation Committee of the American Academy of Neurology which develops critical guidelines for patient care in neurology.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - University of Western Ontario, London Health Sciences Centre
London, ON Canada

Residency - Sunnybrook Health Science Center
Internal Medicine
North York, Ontario,

Internship - Sunnybrook Hospital
Internal Medicine

Medical School - McMaster University Faculty of Health Sciences
Hamilton, ON Canada

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • Teacher of the Year Neurology Residency Cleveland Clinic 2009
  • Serves on the Guideline Development, Dissemination and implementation committee of the American Academy of Neurology
  • Chair, MS quality measures committee, American Academy of Neurology 2015
  • Acting Director, Center for Brain Health, Cleveland Clinic, 2009-2014
  • Chair, CAC committee, Buckeye chapter, National Multiple Sclerosis Society
  • Section Editor, Neurology, Dynamic Medical


  • Neurology

Specialty Interests

multiple sclerosis, Devic's disease, memory impairment, memory loss, mild cognitive impairment, neuroimmunology, neurocognitive disorders including Alzheimer's disease


  • American Academy of Neurology
  • Consortium of Multiple Sclerosis Centers
Research & Publications

Research & Publications

See publications for Alexander Duart Rae-Grant, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/23/2018, Dr. Rae-Grant has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

74 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.9
Courtesy, Respect & Concern 4.9
Knows Medical History 4.7
Time Spent with Patient 4.9
Patient Rating of Doctor 4.9

10 Patient Comments

Reviewed on Oct 24, 2018

dr Rae- grant is the best dr. everything about the mellen center is awesome. all of the staff are very nice. they get..MS

Reviewed on Oct 24, 2018

dr Rae-grant. is best dr.

Reviewed on Aug 28, 2018

Dr. Rae-Grant is a remarkable doctor: knowledgeable, compassionate, and intuitive, he also treats you as a human being, looks at your problems holistically, and doesn't forget about you as soon as you leave his office. A 6 hour drive is worth it every time!

Reviewed on Jul 27, 2018

Dr Rae-Grant was amazing! He was everything you would want in a Dr. he was knowledgeable and attentive. I traveled a far distance to see him and it was worth it! thank you!!!

Reviewed on Jul 25, 2018

Dr. Alexander Rae-Grant is hands down the best Neurologist I have ever been to. His compassion and desire to help me goes beyond anything I could imagine from a caregiver. I am pleased that he is my healthcare provider as he is an exceptional Neurologist.

Reviewed on Jun 16, 2018

Dr Rae Grant is the kindest, sweetest, caring doctor you could ever meet. He was my doctor 10 years ago, and I came back to him now, not caring his miles away for a second opinion and he still is the same doctor, he is the best asset any hospital could have, you are lucky to have him. I am grateful for him.My family and me like him very much.

Reviewed on Jun 14, 2018

because of the doctors speciallty it was difficult to get a timely appointment. I was happy however with the way he spent time with me reviewing my case

Reviewed on Jun 14, 2018

I love Dr. Rae Grant he help me understand MS my body and valadates what I am facong. Every time I leave my appointment I feel better. He is so knowledgeable kind and full of resourceful help. He has excellent bedside manners. This last visit he gave me a referral to tackle a problem I had shamefully suffered with for years. I am very very thankful to have him as my doctor.

Reviewed on Apr 11, 2018

I think Dr. Rae Grant is wonderful

Reviewed on Jan 11, 2018

Dr Rae-Grant has been extremely helpful in managing my health concerns over the past 2 years. He is open minded, responsive, reasonable and supportive - I always feel included in my care. Because of his care I was able to achieve next career milestone and continue to maintain my demanding work schedule relatively okay.

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