Department Mellen Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Consultation and Long-term Care
  • Lumbar Puncture (Spinal Tap)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Autoimmune Encephalitis
  • Devic's Disease (Neuromyelitis Optica)
  • Multiple Sclerosis
  • Neuroimmunology
  • Optic Neuritis
  • Transverse Myelitis
View all 6 Specialties +


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About Alexander Duart Rae-Grant, MD

Dr. Alex Rae-Grant is a Board Certified Staff Neurologist at the Cleveland Clinic. He is a Professor of Medicine (Neurology) at the Cleveland Clinic Lerner College of Medicine. His area of expertise is in multiple sclerosis and related disorders. He is involved in many educational activities at the Clinic and regionally. He has written a number of text books in neurology and multiple sclerosis.

He joined the staff at the Neurological Institute in 2007 and works at the Mellen Center for MS. At the Mellen Center he directs educational efforts including website management, regional and national conferences, and patient education material development. He is active in clinical trials in the treatment of MS with the Experimental therapeutics program at the Mellen Center. He is also the director of the Center for Continuing Education for the Cleveland Clinic.

He has written three textbooks of neurology: "Ultimate review in Neurology",  "Neurology for the House Officer" and "Comprehensive Review in Clinical Neurology A Multiple Choice Question Book for the Wards and Boards", and co-edited another textbook of neurology "The 5 minute consult in Neurology". He has co authored a text book on Multiple Sclerosis with Dr. Jeffrey Cohen titled "Handbook of Multiple Sclerosis" and coedited another textbook with Dr. Robert Fox and Dr. Francois Bethoux entitled "Multiple sclerosis and related disorders". He is active in neurology resident education and medical student education.  He serves on the Guideline Development, Dissemination and Implementation Committee of the American Academy of Neurology which develops critical guidelines for patient care in neurology.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - University of Western Ontario, London Health Sciences Centre
London, ON Canada

Residency - Sunnybrook Health Science Center
Internal Medicine
North York, Ontario,

Internship - Sunnybrook Hospital
Internal Medicine

Medical Education - McMaster University Faculty of Health Sciences
Hamilton, ON Canada

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • Teacher of the Year Neurology Residency Cleveland Clinic 2009
  • Serves on the Guideline Development, Dissemination and implementation committee of the American Academy of Neurology
  • Chair, MS quality measures committee, American Academy of Neurology 2015
  • Acting Director, Center for Brain Health, Cleveland Clinic, 2009-2014
  • Chair, CAC committee, Buckeye chapter, National Multiple Sclerosis Society
  • Section Editor, Neurology, Dynamic Medical


  • Neurology

Specialty Interests

multiple sclerosis, Devic's disease, memory impairment, memory loss, mild cognitive impairment, neuroimmunology, neurocognitive disorders including Alzheimer's disease


  • American Academy of Neurology
  • Consortium of Multiple Sclerosis Centers
Research & Publications

Research & Publications

See publications for Alexander Duart Rae-Grant, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/28/2019, Dr. Rae-Grant has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

77 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.8
Courtesy, Respect & Concern 4.8
Knows Medical History 4.6
Time Spent with Patient 4.8
Patient Rating of Doctor 4.8

12 Patient Comments

Reviewed on May 30, 2019

Dr. Rae Grant is absolutely amazing. I am not sure where I would be, had I not found him 4 years ago. I am convinced there is not a better neurologist in the world.

Reviewed on May 17, 2019

the doctor was very knowledgeable and thorough in the exam. I appreciated his expertise and guidance for hiw to manage this situation

Reviewed on May 14, 2019

Dr. Alexander Rae-Grant and his staff has been the utmost patient and understanding with my disorder and care. They have not given up on me and in turn I have not given up. If I had not found Dr. Grant, I probably would not be here today, already given up on fighting through this disorder and trying. It gets very tiresome trying. But I sincerely feel he and his staff want to give me a quality life as much as I want a quality life, so it makes me want to keep trying, too.

Reviewed on May 14, 2019

I DO recommend Dr. Grant to anyone that asks me who suffer from similar disorder. I have not met another physician that is as sincerely attentive to, truly listens, is brutally honest, explains all the medical terms and procedures that are easily to comprehend, and is very motivating. I am involved in an Encephalopathy group on a social forum, and I am constantly sharing my positive experience these past three or four years with Dr. Grant and his staff as well as The Cleveland Clinic. It is far worth the two hour drive there and two hour drive back home for each appointment, at least to me because I trust them completely with my life.

Reviewed on Apr 24, 2019

dr Rae- grant has always listened and been very knowledgeable and helpful

Reviewed on Apr 24, 2019

Staff - from checkin to coffee on the way out - are excellent. And Dr Rae-Grant is so knowledgeable and kind. I know I'm at the best place when I'm at Cleveland Clinic.

Reviewed on Apr 24, 2019

Dr Rae-Grant is the best. I am fortunate that he is my neurologist.

Reviewed on Apr 12, 2019

Dr. Rae-Grant made me feel so at ease and listened and took his time with me.

Reviewed on Mar 15, 2019

Dr. Rae-Grant is great! I appreciate his time in each appointment and the breadth of information he shares. His resident, however, had an awkward bedside manner.

Reviewed on Mar 1, 2019

the doctor was the best he explained everything in layman's term and he made our trip worthwhile. I have nothing but High Praise for everyone we came in contact with during our visit

Reviewed on Feb 26, 2019

We found Dr. Rae-Grant to be as good or better than we had hoped. His credentials and reputation are outstanding, and know first-hand why. He explained things so we understood and answered all our questions. We did not feel rushed.

Reviewed on Nov 16, 2018

This visit was for a second opinion. If the Clinic wasn't five hours of drive time away I would be a consistent patient for this particular provider. He is THAT good.

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