Department Mellen Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Consultation and Long-term Care
  • Lumbar Puncture (Spinal Tap)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • Autoimmune Encephalitis
  • Devic's Disease (Neuromyelitis Optica)
  • Multiple Sclerosis
  • Neuroimmunology
  • Optic Neuritis
  • Transverse Myelitis
View all 6 Specialties +


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About Alexander Duart Rae-Grant, MD

Dr. Alex Rae-Grant is a Board Certified Staff Neurologist at the Cleveland Clinic. He is a Professor of Medicine (Neurology) at the Cleveland Clinic Lerner College of Medicine. His area of expertise is in multiple sclerosis and related disorders. He is involved in many educational activities at the Clinic and regionally. He has written a number of text books in neurology and multiple sclerosis.

He joined the staff at the Neurological Institute in 2007 and works at the Mellen Center for MS. At the Mellen Center he directs educational efforts including website management, regional and national conferences, and patient education material development. He is active in clinical trials in the treatment of MS with the Experimental therapeutics program at the Mellen Center. He is also the director of the Center for Continuing Education for the Cleveland Clinic.

He has written three textbooks of neurology: "Ultimate review in Neurology",  "Neurology for the House Officer" and "Comprehensive Review in Clinical Neurology A Multiple Choice Question Book for the Wards and Boards", and co-edited another textbook of neurology "The 5 minute consult in Neurology". He has co authored a text book on Multiple Sclerosis with Dr. Jeffrey Cohen titled "Handbook of Multiple Sclerosis" and coedited another textbook with Dr. Robert Fox and Dr. Francois Bethoux entitled "Multiple sclerosis and related disorders". He is active in neurology resident education and medical student education.  He serves on the Guideline Development, Dissemination and Implementation Committee of the American Academy of Neurology which develops critical guidelines for patient care in neurology.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Residency - University of Western Ontario, London Health Sciences Centre
London, ON Canada

Residency - Sunnybrook Health Science Center
Internal Medicine
North York, Ontario,

Internship - Sunnybrook Hospital
Internal Medicine

Medical Education - McMaster University Faculty of Health Sciences
Hamilton, ON Canada

Undergraduate - Yale University
New Haven, CT USA

Professional Highlights

  • Teacher of the Year Neurology Residency Cleveland Clinic 2009
  • Serves on the Guideline Development, Dissemination and implementation committee of the American Academy of Neurology
  • Chair, MS quality measures committee, American Academy of Neurology 2015
  • Acting Director, Center for Brain Health, Cleveland Clinic, 2009-2014
  • Chair, CAC committee, Buckeye chapter, National Multiple Sclerosis Society
  • Section Editor, Neurology, Dynamic Medical


  • Psychiatry and Neurology - Neurology

Specialty Interests

multiple sclerosis, Devic's disease, memory impairment, memory loss, mild cognitive impairment, neuroimmunology, neurocognitive disorders including Alzheimer's disease


  • American Academy of Neurology
  • Consortium of Multiple Sclerosis Centers
Research & Publications

Research & Publications

See publications for Alexander Duart Rae-Grant, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 10/28/2019, Dr. Rae-Grant has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

76 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.8

12 Patient Comments

Reviewed on Jun 11, 2020

Dr Rae-Grant is an excellent physician! I drive 6 hours to see him. I am going to miss his attention to my care.

Reviewed on May 15, 2020

Dr. RaeGrant is an extraordinary physcian that demonstrates outstanding care for his patients.

Reviewed on Mar 26, 2020

I was particularly happy to have scheduled an appointment the day after I called to schedule an appointment with such an experienced, knowledgeable doctor.

Reviewed on Dec 27, 2019

I couldn't have asked for a better doctor. The resident fellow, Dr. Abbatemarco was so thorough in his examination and explaining everything to me. he was very courteous and friendly. Overall, I felt I was cared about.

Reviewed on Dec 27, 2019

always responsive service. Dr Rae-Grant's schedule is always busy, so understandably may need to wait at times

Reviewed on Dec 27, 2019

Very much appreciate Dr. Rae- Grant's continued involvement in my care. Having a complex medical condition stinks, having a dr who genuinely cares, knows your history, and tries to help makes it stink a little less:)

Reviewed on Dec 26, 2019

I was extremely impressed with the doctor. he spent plenty of time with me, discussed everything in detail, and I could truly say I saw how passionate he is about his work and his patients. I'm glad to have found Dr. Rey-Grant and I look forward to trusting him with my medical needs.

Reviewed on Dec 26, 2019

Dr. Rae Grant was very helpful and thorough with my appointment.

Reviewed on Dec 11, 2019

Dr. Rae-Grant was absolutely fabulous. I am a physician and hence have very high expectations for my own providers. He was exactly what I would want in a doc in every manner!!

Reviewed on Dec 10, 2019

Dr Rae Grant is an angel. he is smart, kind and he saved me.

Reviewed on Oct 31, 2019

Dr. Rae-Grant is excellent in all the above categories. I have complete confidence (both in the past and at my recent visit) in him listening, understanding when I describe my symptoms, skilled in exam and very knowledgeable.

Reviewed on Oct 30, 2019

Dr. Rae- Grant is very professional and knowledgeable..we travel from out of town (6 hour drive ) twice a year just so we can see this dr. I always feel validated when I am here. and feel very fortunate to have Dr Rae- Grant as my neurologist...and to have this wonderful facility to come to.. I would highly recommend Dr Rae- Grant and the Mellen center.

Related Videos Featuring Alexander Duart Rae-Grant, MD

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