Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Cancer Center
  • Cardio-Oncology Center
  • Chemotherapy
  • Clinical Trials
  • Medical Oncology
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Adrenal Cancer
  • Bladder Cancer
  • Cancer
  • Facts About Bladder Cancer
  • Kidney Cancer
  • Prostate Cancer
  • Testicular Cancer
View all 7 Specialties +


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About Brian Rini, MD

Brian I. Rini, MD, is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University in Cleveland, Ohio. A Staff member of the Department of Solid Tumor Oncology, Dr. Rini’s work focuses on genitourinary malignancies.

Dr. Rini earned his medical degree at the Ohio State University College of Medicine in Columbus, Ohio. After completing a residency program in internal medicine at University of Chicago Hospitals in Illinois, Dr. Rini was awarded a fellowship in hematology and oncology at the University of Chicago. Dr. Rini was an Assistant Professor at the University of California San Francisco before moving to Cleveland Clinic.

At Cleveland Clinic, Dr. Rini’s primary research has been in renal cell carcinoma (RCC) and prostate cancer, with special focus on antiangiogenic therapy and immunotherapy. Dr. Rini’s research has been published in peer-reviewed journals that include Journal of the National Cancer Institute, Journal of Clinical Oncology, Cancer, Lancet and JAMA. He is a member of the editorial boards of Journal of Clinical Oncology, Cancer and British Journal of Urology.

Certified in Medical Oncology by the American Board of Internal Medicine, Dr. Rini is active in numerous professional organizations, including the American Society of Clinical Oncology (ASCO), American Association for Cancer Research and the Kidney Cancer Association National Medical Advisory Board. He serves on the ASCO Board of Experts and on the External Review Board for the ASCO Cancer Therapy Evaluation Program.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - University of Chicago Hospitals
Hematology / Oncology
Chicago, IL USA

Residency - University of Chicago Hospitals
Internal Medicine
Chicago, IL USA

Internship - University of Chicago Hospitals
Internal Medicine
Chicago, IL USA

Medical School - The Ohio State University College of Medicine and Public Health
Columbus, OH USA

Undergraduate - University of Notre Dame
Notre Dame, IN USA


  • Internal Medicine - Medical Oncology

Specialty Interests

Kidney cancer, renal cell cancer, prostate cancer, adrenal cancer, testicular cancer, bladder cancer, anti-angiogenic therapy, immunotherapy, clinical trials, cancer

Awards & Honors

  • Eugene P. Schonfeld Career Achievement Award (KCA) 2015
  • Sam and Maria Miller Professional Excellence Award (Clinical Research) 2011
  • ASCO/AACR Workshop on Methods in Clinical Cancer Research Merrill J. Egorin Outstanding Mentor Award  2011
  • Case Comprehensive Cancer Center Program Leader of the Year 2011
  • Solid Tumor Oncology Teacher of the Year 2011-2012
  • CCF Department of Molecular Cardiology Page Award for Best Publication 2012
  • Cleveland’s Best Doctors 2005-2015
  • Fellow in FACP 2009
  • CCF Research Programs Council Award Project: Immunoregulatory Effects of Cyclooxygenase-2 (COX-2) Expression in Renal Cell Carcinoma 2006, 2007
  • Department of Defense: New Investigator Award: CTLA-4 Blockade Based Immunotherapy in Prostate Cancer 2004
  • Illinois Medical Oncology Society. Best Submitted ASCO Abstract Award 2001
  • ASCO Abstract Merit Award: Rini BI et al.: Allogeneic Stem Cell Transplantation of Metastatic RCC after Non-myeloablative Chemotherapy 2001
  • ASCO/AACR Methods in Clinical Cancer Research workshop 1999
Research & Publications

Research & Publications

See publications for Brian Rini, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/22/2018, Dr. Rini has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Rini receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Merck & Co., Inc.
  • Pfizer, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

176 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.9
Courtesy, Respect & Concern 5
Knows Medical History 5
Time Spent with Patient 4.9
Patient Rating of Doctor 4.9

15 Patient Comments

Reviewed on Aug 30, 2018

We never had to wait on the receptionist, nurse, scheduler, or Doctor. Dr. Rini had me get an ultrasound and there were no openings. He felt it was a priority to do it immediately so he found a way to fit me in within 45 minutes.

Reviewed on Aug 23, 2018

Dr. Rini is absolutely brilliant and fantastic as a physician and researcher. I consider myself fortunate to be able to consult with him. His Office Administrator Yvonne was incredibly professional and helpful in getting my records for my drs visit. She is one of the very best office administrators I have ever met.

Reviewed on Aug 7, 2018

I felt completely at ease with Dr. Rini. He gave me a fresh perspective on my disease and on treatment choices going forward. He listened patiently to my questions and answered them clearly.

Reviewed on Jul 19, 2018

Dr. Rini is an excellent doctor. He is easy to understand, always takes time to listen to concerns, comfortable to be around and I enjoy my visits with him.

Reviewed on Jun 26, 2018


Reviewed on Jun 7, 2018

i trust dr rini and his team implicitly and i am that with doctors

Reviewed on May 29, 2018

Dr. Rini is a very compassionate doctor. Very knowledgeable yet explains in a way you are able to grasp medical information.

Reviewed on May 29, 2018

A very knowledgeable doctor taking time to go over my medical history explaining the recommended care they were providing

Reviewed on Apr 24, 2018

I am grateful to be in the care of Dr. Rini and his team. They have provided me with excellent care and kindness since the onset of my illness. I have complete trust in their decisions for my care.

Reviewed on Apr 12, 2018

Dr. Rini and the staff are "the best"!

Reviewed on Apr 5, 2018

Dr. Rini is the best of the best!

Reviewed on Apr 5, 2018

Dr. Rini is the best of the best!

Reviewed on Feb 22, 2018

Dr Rini and his intern provided excellent care

Reviewed on Jan 18, 2018

I have complete confidence and trust in Dr. Rini.

Reviewed on Dec 17, 2017

Never seen the billing process but the love, care, timing and process of caring for patients is outstanding.

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