Department Hematology and Medical Oncology
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Cancer Center
  • Cardio-Oncology Center
  • Chemotherapy
  • Clinical Trials
  • Medical Oncology
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Adrenal Cancer
  • Bladder Cancer
  • Cancer
  • Facts About Bladder Cancer
  • Kidney Cancer
  • Non-Clear Cell Kidney Cancer
  • Prostate Cancer
  • Testicular Cancer
View all 8 Specialties +


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About Brian Rini, MD

Brian I. Rini, MD, is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University in Cleveland, Ohio. A Staff member of the Department of Solid Tumor Oncology, Dr. Rini’s work focuses on genitourinary malignancies.

Dr. Rini earned his medical degree at the Ohio State University College of Medicine in Columbus, Ohio. After completing a residency program in internal medicine at University of Chicago Hospitals in Illinois, Dr. Rini was awarded a fellowship in hematology and oncology at the University of Chicago. Dr. Rini was an Assistant Professor at the University of California San Francisco before moving to Cleveland Clinic.

At Cleveland Clinic, Dr. Rini’s primary research has been in renal cell carcinoma (RCC) and prostate cancer, with special focus on antiangiogenic therapy and immunotherapy. Dr. Rini’s research has been published in peer-reviewed journals that include Journal of the National Cancer Institute, Journal of Clinical Oncology, Cancer, Lancet and JAMA. He is a member of the editorial boards of Journal of Clinical Oncology, Cancer and British Journal of Urology.

Certified in Medical Oncology by the American Board of Internal Medicine, Dr. Rini is active in numerous professional organizations, including the American Society of Clinical Oncology (ASCO), American Association for Cancer Research and the Kidney Cancer Association National Medical Advisory Board. He serves on the ASCO Board of Experts and on the External Review Board for the ASCO Cancer Therapy Evaluation Program.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - University of Chicago Hospitals
Hematology / Oncology
Chicago, IL USA

Residency - University of Chicago Hospitals
Internal Medicine
Chicago, IL USA

Internship - University of Chicago Hospitals
Internal Medicine
Chicago, IL USA

Medical Education - The Ohio State University College of Medicine and Public Health
Columbus, OH USA

Undergraduate - University of Notre Dame
Notre Dame, IN USA


  • Internal Medicine - Medical Oncology

Specialty Interests

Kidney cancer, renal cell cancer, prostate cancer, adrenal cancer, testicular cancer, bladder cancer, anti-angiogenic therapy, immunotherapy, clinical trials, cancer

Awards & Honors

  • Eugene P. Schonfeld Career Achievement Award (KCA) 2015
  • Sam and Maria Miller Professional Excellence Award (Clinical Research) 2011
  • ASCO/AACR Workshop on Methods in Clinical Cancer Research Merrill J. Egorin Outstanding Mentor Award  2011
  • Case Comprehensive Cancer Center Program Leader of the Year 2011
  • Solid Tumor Oncology Teacher of the Year 2011-2012
  • CCF Department of Molecular Cardiology Page Award for Best Publication 2012
  • Cleveland’s Best Doctors 2005-2015
  • Fellow in FACP 2009
  • CCF Research Programs Council Award Project: Immunoregulatory Effects of Cyclooxygenase-2 (COX-2) Expression in Renal Cell Carcinoma 2006, 2007
  • Department of Defense: New Investigator Award: CTLA-4 Blockade Based Immunotherapy in Prostate Cancer 2004
  • Illinois Medical Oncology Society. Best Submitted ASCO Abstract Award 2001
  • ASCO Abstract Merit Award: Rini BI et al.: Allogeneic Stem Cell Transplantation of Metastatic RCC after Non-myeloablative Chemotherapy 2001
  • ASCO/AACR Methods in Clinical Cancer Research workshop 1999
Research & Publications

Research & Publications

See publications for Brian Rini, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/1/2019, Dr. Rini has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Rini receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Novartis International, AG
  • Pfizer, Inc.
  • Bristol-Myers Squibb

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

171 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.8
Courtesy, Respect & Concern 4.9
Knows Medical History 4.8
Time Spent with Patient 4.9
Patient Rating of Doctor 4.9

12 Patient Comments

Reviewed on Jul 23, 2019

Dr. Rini is a good communicator and very good at listening / being open to my comments. I enjoyed our time together, and because of his openness to my comments, even more than our last visit. He is very comforting, and in dealing with Cancer, that is very helpful.

Reviewed on Jul 18, 2019

I was referred to Dr Rini by my Oncologist Dr Bir @ HIMG, Huntington, Wv. as a consult which was very good

Reviewed on Jul 2, 2019

Dr. Rini and his team have been very informative , helpful and courteous

Reviewed on May 30, 2019

Professor Dr. Rini is a very special doctor. He is very dedicated to his patient. He is very patience, kind and caring. He was always answering to my questions.

Reviewed on May 10, 2019

I am very fortunate to have Dr. Rini as my oncologist!

Reviewed on Apr 2, 2019

Sat in the room for 1hr and 10 min and then left. After the nurse took the vitals, she said the doc will be in shortly. 70 min is not shortly.

Reviewed on Mar 21, 2019

Dr. Rini is a wonderful doctor. He is easy to talk to and listens completely to any questions or concerns I have. I would definitely recommend him to others.

Reviewed on Mar 19, 2019

Have been a patient of Dr. Rini for over a year. He has always been polite upbeat and comforting to be with.

Reviewed on Mar 19, 2019

Pleasant listened to questions and made sure Dr. Rini had the information

Reviewed on Dec 18, 2018

My provider was very reassuring, I left feeling that chose the right Doctor.

Reviewed on Nov 27, 2018

Dr. Rini combines knowledge with charm. He is blunt and honest which is exactly what I want. At the same time he is compassionate and willing to listen.

Reviewed on Aug 30, 2018

We never had to wait on the receptionist, nurse, scheduler, or Doctor. Dr. Rini had me get an ultrasound and there were no openings. He felt it was a priority to do it immediately so he found a way to fit me in within 45 minutes.

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