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Department Cardiovascular Medicine
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only, Researcher
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Cardiac Rehabilitation
  • Cardiovascular Disease Risk Prevention
  • C-Reactive Protein Testing
  • Preventive Cardiology
  • Preventive Cardiology and Rehabilitation Section
  • Preventive Cardiology Section
View all 6 Treatment & Services +

Specialty in Diseases & Conditions

  • Atherosclerosis
  • Cardiovascular Disease
  • Coronary Artery Disease
  • Heart Disease
  • High Cholesterol
View all 5 Specialties +


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About Stanley Hazen, MD, PhD

Stanley Hazen, MD, PhD, received clinical training in Internal Medicine and subspecialty training in Diabetes, Endocrinology and Metabolism from Barnes/Jewish Hospital, St. Louis, MO, and a PhD in Biophysical Chemistry and Molecular Biology from Washington University School of Medicine, St. Louis, MO. He holds multiple leadership positions at the Cleveland Clinic including chair, Department of Cardiovascular & Metabolic Sciences, Lerner Research Institute, co-Section head, Preventive Cardiology & Rehabilitation, Heart, Vascular & Thoracic Institute, and Director, Center for Microbiome & Human Health. Dr. Hazen sees patients within the Preventive Cardiology Clinic, specializing in preventive cardiovascular medicine care of patients including treatment of hyperlipidemia, hypertension, obesity and diabetes. He also sees patients within the Cardiovascular Rehabilitation program. His research interests include studies of mechanisms for the development of cardiovascular disease, with emphasis on understanding the role of the gut microbiome, inflammation and oxidant stress in the pathogenesis of atherosclerosis and other inflammatory diseases.

A renowned physician scientist, Dr. Hazen has made pioneering discoveries in new understandings of mechanisms contributing to cardiovascular and inflammatory disease research. He is credited with numerous seminal discoveries linking gut microbial pathways to cardiovascular disease pathogenesis, as well as enumerating the role of myeloperoxidase and other inflammatory and oxidative pathways in cardiovascular disease. Dr. Hazen is among the top 0.1% cited researchers in the world with over 140,000 citations. He has published over 475 peer-reviewed articles in top tier basic and clinical journals alike in the fields of atherosclerosis, lipoprotein metabolism, gut microbiome, inflammation, vascular biology, and other topics related to preventive cardiovascular medicine. His research in multiple areas has impacted clinical practice, and lays the foundation for FDA- and EU-cleared diagnostic tests for cardiovascular disease risk assessment in use worldwide. He is listed as inventor on over 100 patents, and his research has helped to spawn pharmaceutical development of cardiovascular disease drugs in clinical trials.

Dr. Hazen has received numerous awards including being the Inaugural recipient of the Top 10 Clinical Discovery of the Year (2011) Award, Clinical Research Forum; the American Heart Association/American Stroke Association “top 10 advance in heart disease and stroke science” award (2013); and the American Heart Association Distinguished Scientist Award (2017). Dr Hazen has been honored with election of membership into honorary societies in both science and clinical arenas alike, including the American Society for Clinical Investigation (ASCI) and the American Association of Physicians (AAP). Dr. Hazen is an elected fellow of the American Association for the Advancement of Science (AAAS). Dr. Hazen also is an elected member of the National Academy of Medicine, USA.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Barnes-Jewish Hospital
St. Louis, MO

Residency - Barnes-Jewish Hospital
Internal Medicine
St. Louis, MO

Medical Education - Washington University School of Medicine
St. Louis, MO

Medical Education - Washington University
St. Louis, MO

Undergraduate - Washington University
St. Louis, MO

Additional Training

Professional Highlights

  • Chair, Gordon Research Conference on Oxygen Radicals
  • Jeffrey M Hoeg Arteriosclerosis, Thrombosis and Vascular Biology Award for Basic Science and Clinical Research
  • Election, Association of American Physicians (AAP)
  • Election, Fellow of American Heart Association Scientific Council for Arteriosclerosis
  • Election, American Society for Clinical Investigation


  • Internal Medicine

Specialty Interests

Cardiovascular risk evaluation, coronary artery disease, high cholesterol, cardiovascular disease, cardiac rehabilitation, C-reactive protein testing, preventive cardiology

Awards & Honors

  • Howard Hughes Medical Institute Research Fellowship for Physicians Award, 1995-1997 
  • AAP, ASCI, and AFMR Certificate of Achievement Award, 1997 
  • Marilyn Hansen American Thoracic Society Award, 1997
  • Junior Faculty Award, American Federation of Medical Research, 1999 
  • Gill Heart Institute Physician Scientist Award, University of Kentucky, Lexington Ky., 2001 
  • Election, American Society for Clinical Investigation, 2003 
  • John J. Ferchill Award for Innovation, Cleveland Clinic, 2004 
  • Nomination, Howard Hughes Medical Institute Investigator Award, 2004 
  • Vice-Chair, Gordon Research Conference on Oxygen Radicals, 2006 
  •  Jeffrey M Hoeg Arteriosclerosis, Thrombosis and Vascular, 2007 

Innovations & Patents

  • Patent Title: Diagnostic Methods for Asthma; U.S. Serial Number 09/253,380
  • Patent Title: Myeloperoxidase, a Risk Indicator for Cardiovascular Disease; U.S., Serial Number 10/039,753
  • Patent Title: Treating Inflammation and Associated Complications; Patent Reference Number 09531-030P01 (Pending)
  • Patent Title: Methods of Identifying Subjects at Increased Risk for Cardiovascular Disease; U.S. Serial Number 60/259,340 (Pending)
  • Patent Title: Monitoring Anti-inflammatory and Anti-oxidant Actions of Therapies; U.S. Serial Number (Pending)
  • Patent Title: Diagnostic Method for Identifying Subjects at Risk for Atherosclerosis and its Complications; U.S. Serial Number (Pending)


  • American Society for Clinical Investigation
  • American Association for the Advancement of Science
  • American Heart Association Scientific Council for Arteriosclerosis
  • American Society for Investigative Pathology
  • American College of Cardiology
Research & Publications

Research & Publications

See publications for Stanley Hazen, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 3/4/2024, Dr. Hazen has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Hazen receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Zehna Therapeutics, LLC

Royalty Payments. Dr. Hazen receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • Zehna Therapeutics, LLC
  • Cleveland HeartLab, Inc. (a wholly-owned subsidiary of Quest Diagnostics, Incorporated)

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Hazen may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • Zehna Therapeutics, LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

45 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.8

13 Patient Comments

Reviewed on Jun 24, 2024

Could not be more favorably impressed with Dr Hazen in all respects, personally and professionally. Kind, concerned, and an expert in his field.

Reviewed on May 13, 2024

Dr. Hazel was thorough and looked through my health record in advance of my appointment.

Reviewed on May 6, 2024

Dr. Hazen is knowledgeable and demonstrates the basic tenets inherent in exceptional patient care.

Reviewed on Apr 8, 2024

A month before the visit I was told by staff all documents to be reviewed were received. As it turned out two documents were not available to Dr Hazen.

Reviewed on Jan 8, 2024

The evidenced based explanations and adjustments to my treatment plan was all that I hoped for. Dr. Hazen made a difficult process thoughtful and understandable.

Reviewed on Jan 8, 2024

Very impressed with Dr Hazen. He addressed my Lp(a), giving ways to help with my LDL, plus cardio daily. Thank you!

Reviewed on Jan 8, 2024

Dr. Hazen was very professional with his knowledge and addressing my Lpa. Treating LDL.

Reviewed on Dec 18, 2023

Dr. Hazen never rushes. He provides me with all of the details associated with options for my care. I feel genuinely cared for by Dr hazen.

Reviewed on Nov 6, 2023

Dr. Hazen was exceptionally thoughtful and spent quite a lot of time reviewing my test results and meetings with other professionals. Apparently he did not have access to the documents that I uploaded to the website and I had to review the lab results verbally. However, despite these technical issues, Dr. Hazen provided excellent recommendations and carefully explained the rationale for his suggestions. I have recommended him to others for preventative cardiology. I give him 5 stars for knowledge, professionalism and personalized care.

Reviewed on Nov 6, 2023

Dr. Hazen reviewed my medical history and ordered an ultrasound of my carotid arteries for my next visit due to my age. He was very thorough and answered all my questions. He is an excellent provider.

Reviewed on Oct 9, 2023

Extremely good provider with patients health of utmost concern.

Reviewed on Jul 31, 2023

Excellent physician whose decion making is evidence based.

Reviewed on Jul 10, 2023

Dr. Hazen was thorough, discussed alternatives of care, and never acted rushed. Everything was explained fully and understandably.

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