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Department Colorectal Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Locations Specialties & Treatments

Treatment & Services

  • Abdominal Perineal Resection
  • Abdominal Surgery
  • Advanced Laparoscopic Surgery
  • Advanced Operative Laparoscopy
  • Anorectal Fistula Treatment
  • Anorectal Surgery
  • Anoscopy
  • Clinical Trials
  • Colectomy
  • Colon And Rectal Surgical Procedures
  • Colon Surgery
  • Colonoscopy
  • Colorectal Cancer - Prevention
  • Colorectal Cancer Diagnosis
  • Colorectal Cancer Research
  • Colorectal Cancer Screening Strategies
  • Colorectal Cancer Treatment
  • Colorectal Surgery
  • Colostomy
  • Fecal Diversion
  • Flexible Sigmoidoscopy
  • Hemorrhoidectomy
  • Ileoanal Pouch
  • Ileostomy
  • Intestinal Stomas
  • J Pouch
  • Laparoscopic Abdominal Perineal Resection
  • Laparoscopic Colectomy
  • Laparoscopic Colon Resection
  • Laparoscopic Colon Surgery
  • Laparoscopic Colorectal Surgery
  • Laparoscopic Fecal Diversion
  • Laparoscopic Ileocolectomy
  • Laparoscopic J-pouch Surgery
  • Laparoscopic Proctosigmoidectomy
  • Laparoscopic Surgery
  • Laparoscopic Surgery for Digestive Diseases
  • Laparoscopy
  • Lesbian Gay Bisexual and Transgender( LGBT Health)
  • Minimally Invasive Colorectal Surgery
  • Pelvic Pouch Surgery for Ulcerative Colitis
  • Pouch Center
  • Pouchoscopy
  • Rectal Cancer Surgery
  • Rectum Reoperative Abdominopelvic Surgery
  • Re-Do Rectal Surgery
  • Reoperative Abdominal and Pelvic Surgery
  • Reoperative Abdominal Surgery
  • Reoperative Pelvic Surgery
  • Reoperative Surgery
  • Resection of Colon and Rectal Diseases
  • Rigid Sigmoidoscopy
  • Robotic Colorectal Surgery
  • Robotic Female Surgery
  • Robotic Surgery
  • Robotic-Assisted Laparoscopic Surgery
  • Rubber Band Ligation Of Hemorrhoids
  • Second Opinion
  • Sphincter Sparing Surgery
  • Stoma Surgery
  • Strictureplasty
  • Surgery
  • Surgery For Carcinoma Of The Colon
  • Surgery For Crohn's Disease
  • Surgery for Crohn's Disease and Ulcerative Colitis
  • Surgery for Rectovaginal Fistula
  • Surgical Management for Ulcerative Colitis
  • Surgical Treatment for Mucosal Ulcerative Colitis
  • Total Abdominal Colectomy
  • Tracheal Intubation
  • Treatment for Anal Fissure
  • Treatment for Anal Fistula
View all 72 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Abscess
  • Adenomatous Polyps
  • Anal Abscesses
  • Anal Cancer
  • Anal Fissures
  • Anal Fistula
  • Benign Anorectal Disease
  • Cancer
  • Cancer of the Colon, Rectum and Anus
  • Carcinoma of the Colon
  • Carcinoma of the small and large bowel
  • Colon Cancer
  • Colon Diseases
  • Colon Polyps
  • Colonic Neoplasia
  • Colovaginal Fistula
  • Colovesticle Fistula
  • Crohn's Disease
  • Diverticulitis
  • Diverticulosis
  • Diverticulum
  • Enterocutaneious Fistula
  • Fissure
  • Hemorrhoids
  • Inflammatory Bowel Disease (IBD)
  • Intestinal Fistula
  • Intestinal Fistulae
  • Intestinal Ischemic Syndrome
  • Large Bowel Cancer
  • Large Intestine Cancer
  • Small Bowel Cancer
  • Small Intestine Cancer
  • Stoma Related Problems
  • Ulcerative Colitis
  • Volvulus
View all 35 Specialties +
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Biography

About Amy Lightner, MD

Dr. Lightner is an Associate Professor of Surgery in the Department of Colon and Rectal Surgery at Cleveland Clinic, OH and associate chief of surgical research, and is the Primary Investigator of the surgical inflammatory bowel disease translational laboratory.  Thus, her time is split between operating, conducting research, and overseeing/directing the research fellows in colorectal surgery.

Prior to coming to Cleveland Clinic, she completed her surgical training in General Surgery at University of California at Los Angeles and post-doctoral work at Stanford University under a California Institute of Regenerative Medicine Training Grant focused on the differentiation pathways of embryonic stem cells.  After completing her fellowship at Mayo Clinic, she stayed on as surgical faculty and was the Director of the Translation, Implementation and Practice Platform within the Center for Regenerative Medicine at Mayo Clinic, enterprise-wide. She was recruited to Cleveland Clinic for her translational laboratory work and clinical trial work in stem cell therapy for Crohn’s disease.

Dr. Lightner has received an extramural career development award to study the use of stem cell based therapies for IBD and has received additional internal funding for ongoing clinical trials in stem cell based therapy for perianal and rectovaginal fistulizing Crohn’s disease.  In addition, she is currently the primary investigator of a multi-center international randomized control trial studying a variation in surgical technique for ileocolic Crohn’s disease and the primary investigator for an industry sponsored trial for stem cell therapy in Crohn’s disease. she is a member of the editorial board of Inflammatory Bowel Diseases, Colorectal Disease and Diseases of the Colon and Rectum, is the surgical chair for the Crohn’s and Colitis Foundation annual meeting, and is the associate chair of the IBD committee within the American Society of Colon and Rectal Surgeons. She is considered a leading expert in regenerative surgery and how it applies to IBD and is regularly invited to give talks nationally and internationally on this topic.

Education & Professional Highlights

Education & Professional Highlights

Appointed
2019

Education & Fellowships

Fellowship - Mayo Clinic
Colon & Rectal Surgery
Rochester, MN USA
2016

Residency - David Geffen School of Medicine @ UCLA
General Surgery
Los Angeles, CA USA
2015

Medical Education - Boston University School of Medicine
Boston, MA USA
2008

Undergraduate - Stanford University School of Medicine
Human Biology
Stanford, CA USA
2003

Additional Training

  • Postdoctoral fellowship in Stem Cell Biology at Stanford University

Professional Highlights

  • Stem cell therapy for Crohn's disease
  • Reconstructive pouch surgery

Certifications

  • Surgery - General Surgery
  • Colon and Rectal Surgery

Specialty Interests

inflammatory bowel disease, stem cell therapy, pouch reconstruction

Awards & Honors

  • Sherman Prize for Emerging Leader in Inflammatory Bowel Disease. Awarded to an emerging leader in inflammatory bowel disease with monetary support for research endeavors. 2018.

    2018 Transform the Practice Award, Translational work cost for “The intra-arterial delivery of mesenchymal stem cells for the treatment of luminal Crohn’s disease: safety, efficacy, and its implications for disease discovery.” Primary Investigator, Mayo Clinic, Rochester MN, 2019-2021.

    Center for Regenerative Medicine Research Award, The local delivery of mesenchymal stem cells for the treatment of fistulas related to Crohn’s disease of the pouch” Primary Investigator, Mayo Clinic, Rochester MN, 2019-2021.

    Center for Regenerative Medicine Research Award, The local delivery of mesenchymal stem cells for the treatment of rectovaginal fistulas related to Crohn’s disease” Primary Investigator, Mayo Clinic, Rochester MN, 2019-2021.

    2018 Department of Surgery Small Research Grant, Translational work cost for Mesenchymal Stem Cells for Fistulizing Crohn’s Disease: Optimizing the Cellular Product for Future Investigation.”Primary Investigator, Mayo Clinic, Rochester MN, 2018-2020.

    2018 Research Career Support and Advancement Award, Translational work cost for “The intra-arterial delivery of mesenchymal stem cells for the treatment of luminal Crohn’s disease: safety, efficacy, and its implications for disease discovery.”, Primary Investigator, Mayo Clinic, Rochester MN, 2018-2020.

    American Society of Colon and Rectal Surgeons Career Development Award, Targeted, intra-arterial delivery of mesenchymal stem cells for the treatment of luminal Crohn’s disease, Primary Investigator, Mayo Clinic, Rochester MN, 2018-2020.

    Advance the Practice Research Award, Imaging biomarkers derived from integrated Time-of-flight (TOF) FDG PET/MR Enterography for differentiating predominantly fibrotic from predominantly inflammatory enteric strictures in patients with Crohn's disease, Co-Investigator, Mayo Clinic, Rochester MN, 2018-2020.

    Center for Regenerative Medicine 2016 Career Development Regenerative Medicine Award, Career Development Award, Translational work cost for “Angiographic delivery of mesenchymal derived stem cells for the treatment of severe medically refractory Ulcerative colitis (UC)”, Mayo Clinic, Rochester, MN, 2016-2018.

    California Institute of Regenerative Medicine (CIRM) Training Grant, Stem Cell Biology (TG2-01159), 2010-2012.

    Training Grant, Molecular and Cellular Immunobiology (5 T32 AI07290), 2010-2011.

Memberships

  • 2018-present Associate Editor, Diseases of the Colon and Rectum

    2017-present Associate Editor, Colorectal Disease

    2017-present Associate Editor, Inflammatory Bowel Disease

    2017-present CCF Abstract Review Committee

    2017-present CCF Chair of Surgical Planning Committee

    2017-present ASCRS Practice Guideline Writing Committee

    2017-present ASCRS Associate Chair of the Inflammatory Bowel Disease Committee

    2015-present Member, European Crohn’s and Colitis Organization

    2015-present Member, American Society of Colon and Rectal Surgeons

    2015-present Member, Surgical Society of the Alimentary Tract

    2015-present Member, Crohn’s and Colitis Foundation

Research & Publications

Research & Publications

See publications for Amy Lightner, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 11/1/2021, Dr. Lightner has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Lightner receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Ossium Health, Inc.
  • Mesoblast, Inc.

Fiduciary Role. Dr. Lightner serves in a fiduciary capacity, such as an elected officer, director or chief medical officer, for the following companies or other entities:

  • RegenTX, LLC

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

119 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.7
Courtesy, Respect & Concern 4.8
Time Spent with Patient 5
Patient Rating of Doctor 4.8

18 Patient Comments

Reviewed on Sep 7, 2021

It was my understanding she was to review my exam and appointment with my gastro doctor so he would make an assessment of the next step in my care. The summary of my appointment did not show that that actually happened. I have not heard from the gastro doctor as well.

Reviewed on Aug 31, 2021

Dr. Lightner was very kind and caring. She explained everything well.

Reviewed on Aug 31, 2021

Wish she would communicate with husband in phone after surgery per my request. I alsoHad complications from one surgery and it took much longer but ince again poor communication to my husband by staff. Dr. Lightner is great!

Reviewed on Aug 24, 2021

Dr Lavery was my doctor before. He saved my life by fixing a fistula and did a second surgery to put my intestines back up and secured them in place. Dr Lightner was not very positive about doing another internal surgery for another fistula. I know her expertise is Crohn's disease. I wonder if there is someone on staff whose expertise is fixing Fistulas and dealing with radiation damage and intestinal loops that have fallen down low.

Reviewed on Aug 17, 2021

Dr. Lightner is the most caring doctor I've ever had. She is one of a kind.

Reviewed on Aug 10, 2021

I ANSWERED THIS BY TEXT YESTERDAY. I WANT TO STRESS AGAIN THAT IT IS DIFFICULT FOR ME TO GIVE ANY NEGATIVE FEED BACK BUT THIS TIME,I FELT AFTER BEING IN SO MUCH PAIN FOR OVER A YEAR AND MAKING A VERY DIFFICULT TRIP TO CLEVELAND FROM GEORGIA BUT WITH GREAT HOPE IN RECEIVING HELP,I NEEDED TO VENT MY DISAPPOINTMENT. I AM NOT SURE THAT DR LIGHTNER EVEN EXAMINED THE LARGE FISSURE I HAVE AND THE WAY MY SKIN WAS (AND IS)PEELING OFF. THE WOUND CARE NURSES SHE CALLED WERE APPRECIATED, THE DR I SAW IN DERMATOLOGY SEEMED CONCERNED AND SPENT A REASONABLE AMOUNT OF TIME WITH ME BUT DID SAY SHE REALLY HAD NOT SEEN ANYTHING LIKE MY CONDITION(ALTHO AT FIRST SIGHT THOUGHT IT WAS CROHNS)BUT TOLD ME THIS WAS NOT HER EXPERTISE AND SHE WAS AN ESTHETIC DERMATOLOGIST. I APPRECIATED HER EFFORT A,LL THE SAME. I BASCIALLY CAME HOME WITH LITTLE TO NO HELP AND ALOT DISAPPOINTMENT AND PAIN AND HAVING SPENT A GREAT DEAL OF MONEY TO SEE DOCTORS I THOUGHT COULD HELP ME

Reviewed on Aug 10, 2021

I had been in sever pain for over a year. I was very hopeful that I would receive help at the Cleveland clinic. However,the Dr spent little time with me and less time doing any exam. She just said she had not seen anything like this condition I had. She did call the wound care nurses and they were very professional and caring. I waited for two days to see dermatology. The Dr I saw was nice and spent some time with me but then said she was not sure what my condition might be . No one really gave me any plan for care. I came home in worse condition due to the pain of travel and disappointment of lack of guidance.

Reviewed on Jun 19, 2021

My doctor is great.

Reviewed on May 4, 2021

I have already recommended Dr. Lightner.

Reviewed on Apr 13, 2021

Dr. Lightner was exactly what I hoped for in trying to solve my medical issues.

Reviewed on Apr 6, 2021

Dr Lightner was very empathic to my current health status

Reviewed on Apr 6, 2021

Dr. Lightner consider all aspects of a procedure.She plans to make sure the patient is comfortable and is very thoughtful and kind during an embarrassing procedure. Dr. Lighter is an outstanding doctor.

Reviewed on Mar 9, 2021

dr. Amy Lightner is a tremendous asset to the Cleveland Clinic. She is conscientious, professional, extremely talented, and very informed when all up-to-date procedures concerning my surgery. I was in the Cleveland clinic twice for a total of 17 days. She saw me every day and was never rushed and took as much time as I needed. she is caring, compassionate, And strives very diligently to ensure the patient's comfort, and peace of mind. She is an unbelievable asset to the Cleveland Clinic and I would return to the clinic based on my experience.

Reviewed on Feb 9, 2021

Dr Lightner is a world class, brilliant physician! She is simply the best

Reviewed on Jan 5, 2021

I took me over a week to get put through to my doctor's office. The scheduling phone number was the only number I had and I was put through to a voice message center several times and was not able to leave messages.

Reviewed on Dec 15, 2020

No bad experience. Dr Lightner was professional, caring, helpful and understanding.

Reviewed on Dec 15, 2020

Dr. lightener was excellent and I look forward to my trip to Cleveland

Reviewed on Dec 3, 2020

*Dr. Lightner and her team are amazing.

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