Department Neuromuscular Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Russian
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Electromyography
  • Neuroimaging (mri, Pet, Spect, Meg Scans)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • ALS with Frontotemporal Dementia
  • Amyotrophic Lateral Sclerosis (ALS)
  • Bulbar Palsy
  • Hereditary Spastic Paraparesis
  • Kennedy's Disease
  • Motor Neuron Disease
  • Multiple System Atrophy
  • Neuromuscular Disease
  • Post-polio Syndrome
  • Primary Lateral Sclerosis
  • Progressive Spinal Muscular Atrophy
  • Pseudobulbar Palsy
  • Spinal Muscular Atrophy
View all 13 Specialties +


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About Erik Pioro, MD, PhD

Erik P. Pioro, MD, PhD, FRCPC, is Director of the Section of Amyotrophic Lateral Sclerosis and Related Disorders at Cleveland Clinic, Cleveland, Ohio, where he specializes in the care of patients with ALS and other complex neurodegenerative motor neuron disorders and runs clinical trials to find effective treatments for these diseases. His primary research focus is using magnetic resonance imaging to identify and monitor the progression of motor neuron degeneration in the brains of patients with ALS and related conditions, and the correlation of imaging changes with human and mouse ALS brain tissue.

Dr. Pioro received his medical degree from the University of Calgary in Alberta, Canada, which was followed by a doctorate in philosophy (PhD) at the University of Oxford in England as a Rhodes Scholar. He completed his neurology residency at the Montreal Neurologic Institute at McGill University in Montreal, Canada, where he also completed a fellowship in magnetic resonance spectroscopy. He also trained as a clinical and research fellow in electromyography/neuromuscular diseases at Cleveland Clinic, where he remained on staff.

Dr. Pioro is the recipient of several awards well as grants from the National Institutes of Health, the ALS Association and the Packard Center for ALS Research at Johns Hopkins University. He is a member of several professional associations, including the American Academy of Neurology, Society for Neurosciences, American Association of Neuromuscular and Electrodiagnostic Medicine and World Federation of Neurology. He serves on the scientific committee for the international ALS CARE Database. He holds the Barry Winovich Chair for ALS Research at the Lerner Research Institute of Cleveland Clinic.

Dr Pioro has published numerous journal articles, book chapters and abstracts on clinical and basic-science topics related to neuromuscular function and disease, particularly in relation to ALS and related disorders. He also serves on the Editorial Board of the journal Neuroscience Imaging, and he serves as an ad hoc reviewer for several journals, including ALS and Motor Neuron Disorders, Annals of Neurology, Brain, Muscle and Nerve, Journal of Neurochemistry, Journal of Neuroimmunology, Journal of Neuroscience, Molecular Neurobiology, and Neurology.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
EMG/Neuromuscular Disease
Cleveland, OH USA

Fellowship - Montreal Neurological Institute and Hospital
Magnetic Resonance Spectrosco
Montreal, Quebec,

Residency - Montreal Neurological Institute and Hospital
Montreal, Quebec,

Residency - Mayo Clinic
Anatomic Pathology
Rochester, MN USA

Residency - University of Calgary

Internship - University of Western Ontario
London, Ontario,

Graduate School - Oxford University Medical School

Medical Education - The University of Calgary Faculty of Medicine
Calgary, Alberta,

Undergraduate - University of Saskatchewan
Saskatoon, Saskatche,

Professional Highlights

  • Barry Winovich Chair in ALS Research


  • Psychiatry and Neurology - Neurology
  • Psychiatry and Neurology - Clinical Neurophysiology

Specialty Interests

Neuromuscular diseases, Motor neuron diseases, including ALS, ALS with frontotemporal dementia (ALS-FTD), primary lateral sclerosis (PLS), Kennedy's disease, Conditions causing pseudobulbar affect (PBA), including stroke, traumatic brain injury, neurodegenerative diseases; Clinical Trials, EMG, Neuroimaging (MRI, MRS).

Awards & Honors

  • Rhodes Scholarship


  • American Academy of Neurology
  • American Association of Electrodiagnostic Medicine
  • Canadian Neurological Society
  • Royal College of Physicians and Surgeons (Canada)
  • Society for Neuroscience
Research & Publications

Research & Publications

See publications for Erik Pioro, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/14/2021, Dr. Pioro has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Pioro receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • ITF Pharma, Inc.
  • Mitsubishi Tanabe Pharma Corporation
  • Avanir Pharmaceuticals, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

91 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Courtesy, Respect & Concern 4.8
Patient Rating of Doctor 4.8

20 Patient Comments

Reviewed on Dec 17, 2020

I always appreciate the attentiveness and time spent with me by Dr Pioro. He's very thorough and knowledgeable

Reviewed on Dec 16, 2020

I have been telling my friends that my experience was that the Cleveland Clinic and their doctors and nurses are like the Disney of healthcare. Everyone was friendly, helpful and understanding.

Reviewed on Dec 3, 2020

Dr. Pioro is the best!

Reviewed on Nov 18, 2020

outstanding physician care

Reviewed on Nov 16, 2020

the doctor was very attentive and listened to me and was concerned about my issues

Reviewed on Nov 9, 2020

Dr. Pioro was a very good listener.

Reviewed on Nov 9, 2020

Even though I was not a patient of Dr. Pioro he explained everything in detail and didn't seem to be in a hurry which I really appreciated.

Reviewed on Oct 27, 2020

Dr Pioro was the best experience I have had with any of my healthcare providers in trying to get to the root of my problem. He is intent in listening to your problem description and provides a clear and precise evaluation.

Reviewed on Oct 12, 2020

dr. Pioro was great.

Reviewed on Oct 12, 2020

he's a great Dr. can't tell me something that's not there.

Reviewed on Oct 8, 2020

I appreciated that Dr. Pioro took the time to listen to what I had to say and my background. knowing my personal history definitely has considerable bearing on my condition.

Reviewed on Sep 1, 2020

I was very appreciative of the time Dr. Pioro afforded me and how closely he listened to my description of issue(s).

Reviewed on Jul 16, 2020

Were extremely pleased with Dr. Pioro's professional demeanor and the thoroughness of his exam and the questions he asked. He acted truly concerned and was very patient and polite. Would highly recommend him to anybody.

Reviewed on Jun 25, 2020

dr.pioro was excellent very thorough and straight forward very concerned for my well being

Reviewed on May 21, 2020

It was a good virtual appointment. Doc was very paitient and through. Look forward to a trip to Cleveland Clinic

Reviewed on May 18, 2020

Dr Pioro is very good at answering our questions and caring about what is going on.

Reviewed on Mar 5, 2020


Reviewed on Feb 12, 2020

dr was very nice

Reviewed on Jan 31, 2020

love Dr Pioro's focused attention (he really listens and isn't in a hurry to get done).

Reviewed on Jan 20, 2020

As always, Dr. Pioro is professional and compassionate!

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