Department Neuromuscular Center
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Russian
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Electromyography
  • Neuroimaging (mri, Pet, Spect, Meg Scans)
View all 2 Treatment & Services +

Specialty in Diseases & Conditions

  • ALS with Frontotemporal Dementia
  • Amyotrophic Lateral Sclerosis (ALS)
  • Bulbar Palsy
  • Hereditary Spastic Paraparesis
  • Kennedy's Disease
  • Motor Neuron Disease
  • Multiple System Atrophy
  • Neuromuscular Disease
  • Post-polio Syndrome
  • Primary Lateral Sclerosis
  • Progressive Spinal Muscular Atrophy
  • Pseudobulbar Palsy
  • Spinal Muscular Atrophy
View all 13 Specialties +


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About Erik Pioro, MD, PhD

Erik P. Pioro, MD, PhD, FRCPC, is Director of the Section of Amyotrophic Lateral Sclerosis and Related Disorders at Cleveland Clinic, Cleveland, Ohio, where he specializes in the care of patients with ALS and other complex neurodegenerative motor neuron disorders and runs clinical trials to find effective treatments for these diseases. His primary research focus is using magnetic resonance imaging to identify and monitor the progression of motor neuron degeneration in the brains of patients with ALS and related conditions, and the correlation of imaging changes with human and mouse ALS brain tissue.

Dr. Pioro received his medical degree from the University of Calgary in Alberta, Canada, which was followed by a doctorate in philosophy (PhD) at the University of Oxford in England as a Rhodes Scholar. He completed his neurology residency at the Montreal Neurologic Institute at McGill University in Montreal, Canada, where he also completed a fellowship in magnetic resonance spectroscopy. He also trained as a clinical and research fellow in electromyography/neuromuscular diseases at Cleveland Clinic, where he remained on staff.

Dr. Pioro is the recipient of several awards well as grants from the National Institutes of Health, the ALS Association and the Packard Center for ALS Research at Johns Hopkins University. He is a member of several professional associations, including the American Academy of Neurology, Society for Neurosciences, American Association of Neuromuscular and Electrodiagnostic Medicine and World Federation of Neurology. He serves on the scientific committee for the international ALS CARE Database. He holds the Barry Winovich Chair for ALS Research at the Lerner Research Institute of Cleveland Clinic.

Dr Pioro has published numerous journal articles, book chapters and abstracts on clinical and basic-science topics related to neuromuscular function and disease, particularly in relation to ALS and related disorders. He also serves on the Editorial Board of the journal Neuroscience Imaging, and he serves as an ad hoc reviewer for several journals, including ALS and Motor Neuron Disorders, Annals of Neurology, Brain, Muscle and Nerve, Journal of Neurochemistry, Journal of Neuroimmunology, Journal of Neuroscience, Molecular Neurobiology, and Neurology.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
EMG/Neuromuscular Disease
Cleveland, OH USA

Fellowship - Montreal Neurological Institute and Hospital
Magnetic Resonance Spectrosco
Montreal, Quebec,

Residency - Montreal Neurological Institute and Hospital
Montreal, Quebec,

Residency - Mayo Clinic
Anatomic Pathology
Rochester, MN USA

Residency - University of Calgary

Internship - University of Western Ontario
London, Ontario,

Graduate School - Oxford University Medical School

Medical Education - The University of Calgary Faculty of Medicine
Calgary, Alberta,

Undergraduate - University of Saskatchewan
Saskatoon, Saskatche,

Professional Highlights

  • Barry Winovich Chair in ALS Research


  • Neurology
  • Neurology - Clinical Neurophysiology

Specialty Interests

Neuromuscular diseases, Motor neuron diseases, including ALS, ALS with frontotemporal dementia (ALS-FTD), primary lateral sclerosis (PLS), Kennedy's disease, Conditions causing pseudobulbar affect (PBA), including stroke, traumatic brain injury, neurodegenerative diseases; Clinical Trials, EMG, Neuroimaging (MRI, MRS).

Awards & Honors

  • Rhodes Scholarship


  • American Academy of Neurology
  • American Association of Electrodiagnostic Medicine
  • Canadian Neurological Society
  • Royal College of Physicians and Surgeons (Canada)
  • Society for Neuroscience
Research & Publications

Research & Publications

See publications for Erik Pioro, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/25/2019, Dr. Pioro has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Pioro receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • ITF Pharma, Inc.
  • Mitsubishi Tanabe Pharma Corporation

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

98 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.9
Courtesy, Respect & Concern 4.9
Knows Medical History 4.6
Time Spent with Patient 4.8
Patient Rating of Doctor 4.8

18 Patient Comments

Reviewed on Jun 17, 2019

Dr. Pioro was very friendly and informative. He provided a very comprehensive discussion about the medical problem and steps to take. This was an excellent experience!

Reviewed on Jun 3, 2019

my physical problems have been going on for over 13 years and none of the local Doctors have been able to pinpoint my problems. Dr. Pioro was unbelievable, he systematically went through each of my concerns and for the first time in year's I'm optimistic about coming up with a definitive diagnosis. I was really impressed!!!!!

Reviewed on May 17, 2019

Incredible the EXTREMELY THOROUGH nature of Dr Pioro's exam. The amount of time he spent with me was incredible. Extremely attentive listener. An incredible physician. I did have to wait for him past my appointment time but that is to be expected. There is no way to appropriately schedule problems perfectly. He was well worth the wait!! An extremely compassionate and caring physician! He is INCREDIBLE!

Reviewed on Apr 25, 2019

This was an excellent meeting with Dr. Pioro and Claudia and their staff. They took the time and patience to examine me and explain to me their assessments. A wonderful doctor, the best I have seen. The Cleveland Clinic accomodated me, my stay there was a great experience. All in all, I don't think there is any room for improvement.

Reviewed on Feb 1, 2019

Dr Pioro was amazing. His opinions are so much appreciated and his professionalism beyond question. I feel confident ant hopeful working with him.

Reviewed on Jan 28, 2019

Dr. Pioro is the best neurologist I have seen. He gave me hope in finding some relief from pain from my rare disease. I look forward to seeing him again.

Reviewed on Jan 17, 2019

Dr Piori is the best!! Taked as much time as needed. genuinely concerned. Well worth enduring any amount of wait time.

Reviewed on Jan 14, 2019

Dr. Pioro, Claudia & staff have always been very helpful & have went above my expectations in providing prompt, respectful, & the best medical care I have ever received. I have been a patient now since 2013, I was referred here for 1 thing & learned so much more! Without that referral I would absolutely be in a nursing facility or worse. I am so grateful for the care I have received here. The only thing I can think of that could be better is the accessibility to parking garages and the maneuverability of the campus.

Reviewed on Jan 14, 2019

I would most definitely recommend Dr Pioro to anyone in need of his specialty. Without Dr Pioro I fear I would have not gotten my diagnosis and the treatment I so desperately needed. My life has changed dramatically since I met Dr Pioro in the best possible way given my condition. He provided answers to my husband and I that we had been searching for. He was able to explain, diagnose, and treat a very rare condition. I owe my quality of life to Dr Pioro. I couldn't ask for a more reception and caring physician.

Reviewed on Dec 20, 2018

Doctor was held up due to circumstances beyond his control. Nurse was very helpful.

Reviewed on Dec 13, 2018

we waited and waited and waited! We waited for one hour (no one ever checked in with us concerning the long delay); I finally opened our door and looked down the hallway and that was where I finally saw my Doctor; he then came to the exam room.

Reviewed on Dec 11, 2018

Dr was very informative and listened to me when explaining what is going on.

Reviewed on Nov 9, 2018

Dr . Piero was thorough and excellent

Reviewed on Oct 17, 2018

Dr Pioro is a the neurologist who treats my ALS. He is a such great doctor that gives me good advice and treatment. He also has an excellent team. We greatly appreciated his help.

Reviewed on Sep 21, 2018

Doctor explained everything in detail and very patient.

Reviewed on Sep 21, 2018

Very thorough doctor. Very detailed.

Reviewed on Sep 21, 2018

Dr., Erik Pioro had the best people skills of any physician I have ever met.

Reviewed on Sep 7, 2018

Excellent visit with Dr. Eric Pioro.He was extremely thorough.

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