Apostolos Kontzias, MD

Department Rheumatologic and Immunologic Disease
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, Greek
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • General Rheumatology
  • General Rheumatology including Lupus
  • Joint Aspiration
  • Medical Management of Early Osteoarthritis
  • Musculoskeletal Evaluation
  • Musculoskeletal Treatment For Joint Pain
  • Pericardial Diseases Center
  • Rheumatology
View all 8 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult Onset Still's Disease
  • Antiphospholipid Syndrome
  • Arthritic Knee Problems
  • Arthritis
  • Arthritis of the Foot and Ankle
  • Arthritis Of The Hip
  • Arthritis Of The Knee
  • Autoinflammatory Syndromes
  • Blau Syndrome
  • Bursitis
  • Connective Tissue Diseases
  • Connective Tissue Disorders
  • Cryopyrin Associated Periodic Syndromes (CAPS)
  • Familial Cold Urticaria
  • Familial Mediterranean Fever
  • Familial Mediterranean Fever (FMF) Syndrome
  • Fever of Unknown Origin (FUO)
  • Hip Pain
  • Hyper IgD syndrome (HIDS)
  • Inflammatory Arthritis
  • Joint Disorders
  • Knee Joint Disorders
  • Knee Pain
  • Lupus
  • Majeed Syndrome
  • Muckle-Wells syndrome (MWS)
  • Musculoskeletal Disorders
  • Musculoskeletal Pain
  • Myositis
  • Osteoarthritis Of The Hips And Knees In The Elderly
  • Osteopenia
  • Painful Joints
  • Periodic Fever Syndromes
  • Periodic Fevers, Aphthous Stomatitis, Pharyngitis, and Adenopathy (PFAPA) Syndrome
  • Rheumatoid Arthritis: How to Treat
  • SAPHO syndrome
  • Schnitzler Syndrome
  • Seronegative Spondyloarthropathies
  • Shoulder Arthritis
  • Spondylitis
  • TNF-Receptor Associated Periodic Syndrome (TRAPS)
View all 41 Specialties +


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About Apostolos Kontzias, MD

Apostolos Kontzias, MD, is a Staff Physician in the Orthopedic and Rheumatologic Institute at Cleveland Clinic. Dr. Kontzias is also an Assistant Professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. Dr Kontzias has a research focus on autoinflammatory syndromes which are conditions of innate immunity frequently genetically inherited presenting with fever, rash and arthritis. He is the Director of the Autoinflammatory Clinic which operates within the The R. J. Fasenmyer Center for Clinical Immunology. He has established a biobank registry in collaboration with the Genomics Institute at the Cleveland Clinic and has forged national and international collaborations to study these conditions.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - National Institutes of Health
Bethesda, MD USA

Residency - Lincoln Medical and Mental Health Center
Internal Medicine
Bronx, NY USA

Medical School - University of Athens Faculty of Medicine, National & Kapodistrian
Athens, Greece


  • Internal Medicine
  • Internal Medicine - Rheumatology

Specialty Interests

Autoinflammatory diseases Innate Immunity diseases Periodic Fever syndromes Fever of Unknown Origin Familial Mediterranean Fever TNF receptor associated periodic syndrome Cryopyrin associated periodic syndromes (Muckle Wells, Familial cold urticarial, NOMID) Adult onset Still's Disease Spondyloarthritis Ankylosing spondylitis

Research & Publications

Research & Publications

See publications for Apostolos Kontzias, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/29/2016, Dr. Kontzias has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

223 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.8 out of 5
Explains 4.8
Listens 4.9
Courtesy, Respect & Concern 4.9
Knows Medical History 4.7
Time Spent with Patient 4.9
Patient Rating of Doctor 4.8

21 Patient Comments

Reviewed on Mar 22, 2017

Dr. Kontzias was the first doctor who was able to diagnosis my condition (SAPPHO) after 7 months of pain and visits to 10+ doctors at Emory, MD Anderson, and other centers of excellence. He is a hero in my family!

Reviewed on Mar 1, 2017

Dr. Kontzias and his fellow were both wonderful. They both were sincere in their concern for my health and asked questions I would have never thought were of importance. They also explained WHY those questions were important and Dr. Kontzias explained what labs he was ordering and why, as well as what medication he was changing and why.

Reviewed on Feb 3, 2017

Offered OT for finger splints if I felt I wanted to try. Also offered nsaid gel for pain

Reviewed on Jan 26, 2017

Sorry for the all caps but Dr. Kontzias is AWESOME. I am so happy that I was finally sent a survey about him. He is the best doctor ever! In addition to being very charismatic, Dr. Kontzias has been kind, caring, and compassionate. I am the type of rheumatology patient who has a constellation of signs and symptoms, but no explicit diagnosis at this time. The original reason I was referred to a rheumatologist was because I have late onset Raynaud's Phenomenon. Although I know Dr. Kontzias will provide a diagnosis if or when appropriate, he has always been focused on me - not any disease label. He is concerned about any discomfort or pain I may be having, and about anything that is detrimental to my quality of life. I so look forward to my appointments with Dr. Kontzias - the date of any upcoming appointment I have with him is like another holiday on my calendar! Thank you for asking for my opinion and for giving me the chance to offer praise about Dr. Kontzias.

Reviewed on Jan 20, 2017

Dr. K was excellent

Reviewed on Jan 16, 2017

I think Dr. Kontzias is a great doctor. My sister, who is a nurse, after sitting in on my appointment asked him if he would accept her as a patient if needed in the future. She was very impressed with him!

Reviewed on Jan 11, 2017

I am so impressed by my overall Cleveland Clinic experience! I especially appreciate EVERYONE'S friendliness & willingness to listen & trust the information I provided!

Reviewed on Dec 27, 2016


Reviewed on Nov 30, 2016

all good. my wife and I were not planning on being there so long but considering I've waited five years to find an expert that wouldn't look at me like I'm crazy I feel that time was definitely exceptional and well spent. thank you all and please keep up the good work.

Reviewed on Nov 7, 2016

Dr. Kontzias and I have a mutual, open two way communication on my treatment plan with an explanation of the rationale and a plan. He is EXCELLENT and helping me understand the newest research on meds and my diseases.

Reviewed on Oct 26, 2016

very smoothly run on all counts. very pleasant people

Reviewed on Sep 27, 2016


Reviewed on Sep 9, 2016

He's excellent!

Reviewed on Sep 6, 2016

One of the best physicians I have ever seen. A very caring individual who provides excellent care.

Reviewed on Aug 30, 2016

always very helpful

Reviewed on Aug 16, 2016

Words to describe Dr. Kontzias are exceptional, superb, extraordinary, outstanding, wonderful, listens diligently, phenomenal, etc.

Reviewed on Jun 13, 2016


Reviewed on May 24, 2016

Doctor was/is very thorough.

Reviewed on May 24, 2016

He is intelligent and kind. He spoke to me like an equal, which I appreciate. Dr. K understands that he knows that I live with the illness.

Reviewed on May 2, 2016

The physician is great. In addition to being a very competent physician, he is a nice personable caring individual. He asked appropriate questions. He inquired about a hospitalization I had in January. He have obviously reviewed my chart before coming in and knew all of my comorbidities. When I told him that I had two articles published about me in April he seemed genuinely interested and seemed to want to know more about them. I like physicians who I can establish a more personal relationship with. I have no idea if he treats all of his patients that way but to me, a Clinic frequent flier, he is great. I have recommended him to several people.

Reviewed on Apr 29, 2016

Dr. Kontzias is one of the best doctors I have ever had. He makes me feel like his only patient for the day because he never rushes me, he patiently listens to and then thoroughly answers all of my questions and concerns, he explains things in a way that he's sure I will understand, he always goes over my options with me and most importantly, it is evident that he is invested in and genuinely cares about his patients. As all doctors should be. Furthermore, he approaches everything with an optimistic attitude, making it so that challenging or overwhelming situations and/or chronic illnesses do not defeat or define me. I consider myself very fortunate to have him for my Rhuematologist.

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