COVID-19 booster guidance for Moderna and Johnson & Johnson

The Centers for Disease Control and Prevention (CDC) and U.S. Food and Drug Administration (FDA) have approved a booster dose of the COVID-19 Moderna and Johnson & Johnson (Janssen) vaccines for certain individuals.  

Guidance for the Moderna COVID-19 vaccine

A booster dose of the Moderna vaccine has been approved for the following groups, at least six months after completion of their second vaccine: 

  • Individuals 65 years and older 
  • Individuals ages 18-64 who have underlying medical conditions that place them at higher risk for severe COVID-19.  The CDC has indicated that this is a determination made by the vaccine recipient, but those eligible are encouraged to talk to their healthcare providers if they have any questions.
  • Individuals ages 18-64 who live in long-term care settings 
  • Individuals ages 18-64 who work or live in high-risk settings. The CDC has indicated that this is a determination made by the vaccine recipient. This includes healthcare workers.

Guidance for the Johnson & Johnson COVID-19 vaccine

A booster dose of the Johnson & Johnson vaccine has been approved for individuals 18 years of age and older at least two months after their initial one-dose vaccine.  

Can I receive a different booster from the original vaccine product I received? 

The FDA and CDC have authorized individuals to receive a booster dose that is a different brand than their initial vaccines. For example, someone who received an initial dose of the Johnson & Johnson vaccine, can receive a Pfizer or Moderna booster dose.  

What booster product is Cleveland Clinic offering?

Cleveland Clinic is currently offering Pfizer booster doses. Patients and caregivers can schedule their Pfizer booster through MyChart or by calling 216.448.4117 at any of our vaccination locations. Our schedulers are available Tuesday – Friday from 9 a.m. to 4 p.m. Click here to view instructions on how to schedule a Pfizer booster in MyChart.

What if I want a Moderna booster?

More information will be available in the coming days regarding scheduling a Moderna booster dose at a Cleveland Clinic location as well as walk-in options for caregivers. We appreciate your patience.

Can I get a booster outside of Cleveland Clinic?

Caregivers seeking alternative locations can receive their COVID-19 vaccine and booster doses at any available location including local retail pharmacies.

Is a booster dose different than a third dose for people with compromised immune systems?

Yes. A booster dose is given a letast six months following the second dose of the Pfizer or Moderna COVID-19 vaccine. For people with compromised immune systems, the third dose must be given at least 28 days after a patient’s second dose.

The COVID-19 vaccines are the best way to protect yourself and others from severe illness and death from COVID-19.  We encourage everyone who is eligible to receive a COVID-19 vaccine.