What are the side effects of BOTOX® injections?

The most common side effects of BOTOX® injections are temporary bruising and slight pain with injection. Headaches, which go away in 24 to 48 hours, can occur, but this is rare.

A very small percentage of patients may develop eyebrow or eyelid drooping, drooping of the corner of the mouth, or inability to use a straw, depending on where the BOTOX® is injected. For this reason, one should not rub the treated area for 12 hours after injection, or lie down for three to four hours after injection. No serious side effects have been noted when using BOTOX® at the dermatologic (prescribed) doses.

Who should NOT receive BOTOX® injections?

Patients who should not use BOTOX® are those who:

  • are pregnant;
  • are breastfeeding;
  • have a neurological disease; or,
  • are allergic to albumin or a constituent (part) of the preservative.

As BOTOX® does not work for all wrinkles, a consultation with a doctor is recommended.

Last reviewed by a Cleveland Clinic medical professional on 03/23/2016.


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