What is the outlook for patients with eosinophilic granulomatosis with polyangiitis (EGPA)?

Although EGPA can be an increasingly serious illness, many patients do extremely well. On average, after 5 years of illness, more than 80% of patients survive the effects of EGPA. How patients with EGPA do is strongly related to how severe their illness is.

The best opportunity to limit damage to the organs is when treatment starts right away and is carefully supervised by a doctor who is knowledgeable about EGPA. Even patients who have the most severe EGPA can go into remission when they are treated quickly and followed closely.

After a patient goes into remission, it is possible that the EGPA can come back ("relapse"). People with asthma or nasal allergies can often have worsening of these symptoms that is separate from vasculitis.

Relapses involving vasculitis occur in about 30% to 50% of people with EGPA. These relapses may be similar to what the person experienced at the time of their vasculitis diagnosis.

It’s possible to reduce the likelihood of a severe relapse by reporting any new symptoms to the doctor right away, seeing the doctor on a regular basis, and having regular checkups with laboratory tests and imaging. The treatment approach for relapses is similar to that of newly diagnosed disease, and it’s possible again for these patients to go into remission again.

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