What is the outlook for people with acromegaly?

Outcomes for people with acromegaly depend on how severe the disease is and how effectively therapies treat the symptoms. Many people see a significant improvement in symptoms after treatment.

If it is not treated, acromegaly can cause disabling and disfiguring symptoms. These symptoms can greatly affect the person’s self-image and quality of life. Support groups help some people deal with the challenges they face because of acromegaly.

Health complications such as heart disease or Type 2 diabetes can also decrease quality of life and even shorten the lifespan. In the most severe cases, these complications can cause life-changing effects.

Last reviewed by a Cleveland Clinic medical professional on 03/16/2018.


  • National Institute of Diabetes and Digestive and Kidney Diseases. Acromegaly. Accessed 4/2/2018.
  • The Pituitary Society. Acromegaly. Accessed 4/2/2018.
  • National Center for Advancing Translational Sciences. Acromegaly. Accessed 4/2/2018.

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