How is epididymitis treated?

Epididymitis caused by bacteria is treated with antibiotics, most often doxycycline (Oracea®, Monodox®), ciprofloxacin (Cipro®), levofloxacin (Levaquin®), or trimethoprim-sulfamethoxazole (Bactrim®). Antibiotics are usually taken for 1 to 2 weeks.

Men who have epididymitis can also relieve their symptoms by:

  • Resting
  • Elevating the scrotum
  • Applying ice packs to the affected area
  • Drinking fluids
  • Taking anti-inflammatory medications for the pain

What are complications of epididymitis?

If epididymitis is not treated, complications can develop, including an abscess (pus-filled sac) in the scrotum. The scrotum’s skin may open because of swelling and infection.

In rare cases, epididymitis can cause fertility problems in men. Early diagnosis and treatment can help prevent these complications.

Last reviewed by a Cleveland Clinic medical professional on 02/07/2018.


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