How is Stevens-Johnson syndrome treated?

  • Stopping the medication that has caused the problem
  • Replacing electrolytes with intravenous (IV) fluids
  • Using non-adhesive dressings
  • Using high-calorie food, possibly by tube-feeding, to promote healing
  • Using antibiotics when needed to prevent infection
  • Providing pain relief medications
  • Treating in an intensive care or burn unit in a hospital
  • Using specialist teams from dermatology and ophthalmology (if eyes are affected)
  • In some cases, treating with IV immunoglobulin or amniotic membrane grafts (for eyes)

What are the complications of Stevens-Johnson syndrome?

The most severe complication of SJS and toxic epidermal necrolysis (TEN) is death. Death happens in about 10% of cases of SJS, and about 50% of TEN. Other complications could include:

  • Pneumonia
  • Sepsis (massive bacterial infections)
  • Shock
  • Multiple organ failure

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