What is the prognosis (outlook) for patients who have leukoplakia?
Anyone who has leukoplakia should follow up with a doctor every three to six months, with biopsies as needed, to watch for possible changes in the condition.
Even if patches are surgically removed, an examination every six to 12 months is recommended, because leukoplakia frequently returns. Treatment sites that remain free of abnormalities for three years may not need to be observed any more.
If leukoplakia returns after treatment, you should continue to have follow-up examinations for as long as your healthcare provider recommends.