How is persistent pulmonary hypertension in the neonate (PPHN) diagnosed?

The following tests may be used to diagnose PPHN:

  • Blood tests.
  • Pulse oximetry (a noninvasive way to measure oxygen levels in the blood).
  • Chest X-ray.
  • Echocardiogram (a detailed ultrasound of the baby’s heart).

Last reviewed by a Cleveland Clinic medical professional on 10/01/2019.


  • National Association of Neonatal Nurses. PPHN Parent Info Page.
  • Steinhorn RH. Neonatal pulmonary hypertension. Pediatr Crit Care Med. 2010;11(2 Suppl):S79-84.

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