How is bullous pemphigoid diagnosed?

Your doctor will usually begin an exam to see if you have bullous pemphigoid by asking a series of questions, such as:

  • When did your symptoms begi?
  • Do your blisters have pus or blood?
  • Have you had a fever?
  • Have you started any new medications?

Your doctor may then perform tests to confirm the diagnosis. These include blood tests and a skin biopsy.

Last reviewed by a Cleveland Clinic medical professional on 10/10/2019.


  • Kirtschig G, Middleton P, Bennett C, Murrell DF, Wojnarowska F, Khumalo NP. Interventions for bullous pemphigoid. Cochrane Database of Systematic Reviews 2010, Issue 10.
  • Joly P, Benichou J, Lok C, Hellot MF, Saiag P, Tancrede-Bohin E, Sassolas B, Labeille B, Doutre MS, Gorin I, Pauwels C, Chosidow O, Caux F, Estève E, Dutronc Y, Sigal M, Prost C, Maillard H, Guillaume JC, Roujeau JC. Prediction of survival for patients with bullous pemphigoid: a prospective study. Arch Dermatol. 2005 Jun;141(6):691-8.
  • American Osteopathic College of Dermatology. Bullous pemphigoid. Accessed 11/27/2019.

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