How is fifth disease diagnosed?

Fifth disease is usually diagnosed based on your symptoms. The “slapped cheek” rash is a strong sign of this condition — and when it’s accompanied by the other main flu-like symptoms — your healthcare provider can usually diagnose fifth disease in the office without any other tests. In rare cases, your provider may order blood tests to confirm fifth disease.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy