How is inclusion body myositis (IBM) treated?

There is no effective course of treatment for IBM. The disease is not responsive to corticosteroids and immunosuppressive drugs – two drugs that often treat inflammatory or autoimmune conditions. Some evidence suggests that intravenous immunoglobulin may help slightly in a small number of cases, but the benefit does not last long.

Physical therapy may be helpful in maintaining mobility and helping to keep joints mobile. Other therapy, including treatments for the swallowing problems, is symptomatic and supportive.

Last reviewed by a Cleveland Clinic medical professional on 04/02/2019.

References

  • Ropper AH, Samuels MA, Klein JP. Chapter 48. Diseases of Muscle. In: Ropper AH, Samuels MA, Klein JP. eds. Adams & Victor's Principles of Neurology, 10e. New York, NY: McGraw-Hill; 2014.
  • Dalakas MC. Chapter 388. Polymyositis, Dermatomyositis, and Inclusion Body Myositis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 18e. New York, NY: McGraw-Hill; 2012.
  • World Gastroenterology Organisation Practice Guidelines. Dysphagia. Accessed 4/3/2019.
  • Genetic and Rare Diseases Information Center. Inclusion body myositis. Accessed 4/3/2019.

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