How can myelofibrosis be prevented?

Myelofibrosis cannot be prevented, but allogeneic hematopoietic cell transplantation (HCT) may be a potential cure. The procedure involves replacing a patient’s immune system with that of a suitable donor. This new immune system seeks out and kills the cancerous cells in the bone marrow of the myelofibrosis patient as well as provides healthy blood-making bone marrow cells. Immediately before the transplant, the patient must undergo chemotherapy and/or radiation therapy to suppress his or her own immune system, so the cells from the donor will take.

HCT carries a high risk of complications and is only suitable for certain patients. The risk of a complication is higher for people with other medical conditions. Various factors must be taken into account for patients who may be candidates for the procedure, including their age, the severity of their symptoms, other risk factors, and the likelihood of success.

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