How is pouchitis treated?

Pouchitis is usually treated with a 14-day course of antibiotics. The doctor may also recommend probiotics (“good” bacteria that normally live in the digestive tract) such as Lactobacillus, Bifidobacterium and Thermophilus.

Some patients may develop chronic (long-term) pouchitis A low-carbohydrate and/or low-fiber and high protein diet may help relieve symptoms of chronic pouchitis, or the patient may require therapy with anti-inflammatory agents or even biological agents. Antidiarrheal agents may be used to treat frequent or loose bowel movements.

What can be expected after treatment for pouchitis?

Patients who are having a first episode of pouchitis are almost always treated successfully with antibiotics. However, in many cases, the disease relapses (comes back) at a later time.

Last reviewed by a Cleveland Clinic medical professional on 01/16/2019.

References

  • Shen B, Lashner BA. Diagnosis and Treatment of Pouchitis. Gastroenterol Hepatol (N Y) May 2008;4(5): 355–361.
  • Shen B. Pouchitis: What Every Gastroenterologist Needs to Know. Clinical Gastroenterology and Hepatology, December 2013 Volume 11, Issue 12, Pages 1538–1549. DOI: https://doi.org/10.1016/j.cgh.2013.03.033
  • Achkar J-P, Al-Haddad M, Lashner B, et al. Differentiating Risk Factors for Acute and Chronic Pouchitis. Clinical Gastroenterology and Hepatology 2005;3:60–66.
  • Gionchetti P, Calafiore A, Riso D, et al. The role of antibiotics and probiotics in pouchitis. Ann Gastroenterol. 2012; 25(2): 100–105.

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