How are the causes of changes in urine diagnosed?

If you have changes in the color, odor, or consistency of your urine that last more than a few days and do not seem tied to any diet or medicine changes, you should contact your healthcare provider.

Your doctor will most likely begin your appointment by asking you to describe the changes. This includes asking about how long you have had these changes and whether you have seen any blood in your urine. The doctor will also ask about any dietary or medicine changes and how much water or liquids you are drinking. He or she will also ask if you are feeling pain when urinating or have pain in your abdomen or bladder area. You may also be asked about any appetite or thirst changes. These questions will help determine if an underlying condition could be causing the changes in your urine. If the doctor remains concerned that something abnormal is going on, a urine sample may be taken. This sample will be tested. The test looks for blood, protein, inflammation (urinalysis), and possibly bacteria that could be causing an infection (urine culture) if a UTI is suspected.

A blood test may also be taken to check for possible kidney damage, diabetes, or a buildup of liver enzymes.

Last reviewed by a Cleveland Clinic medical professional on 01/06/2020.

References

  • American Kidney Fund. Blood in urine (hematuria). Accessed 1/8/2020.
  • Ferri FF. Ferri's Differential Diagnosis: A practical guide to the differential diagnosis of symptoms, signs and clinical disorders. 2nd ed. Philadelphia, Pa.: Mosby Elsevier; 2011:82.
  • Foot CL, et al. Uroscopic rainbow: Modern matula medicine. Postgraduate Medical Journal. 2006;82:126.
  • Gerber GS, et al. Evaluation of the urologic patient: History, physical examination, and urinalysis. In: Wein AJ, et al. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2007.
  • Israni AK, Kasiske BL. Laboratory assessment of kidney disease: clearance, urinalysis, and kidney biopsy. In: Brenner BM, ed. Brenner and Rector's The Kidney. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 23.
  • Landry DW, Bazari H. Approach to the patient with renal disease. In: Goldman L, Ausiello D, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 116.
  • McPherson RA, et al. Basic examination of urine. In: McPherson RA, et al. Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. Philadelphia, Pa.: Saunders Elsevier; 2007.
  • US Department of Health and Human Services, National Institute of Diabetes and Digestive and Kidney Disease. Albuminuria: Albumin in the Urine. Accessed 1/8/2020.
  • American Kidney Fund. Protein in urine. Accessed 1/8/2020.
  • National Kidney Foundation. What You Should Know About Albuminuria (Proteinuria). Accessed 1/8/2020.

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