Are there any treatments for cognitive impairment in multiple sclerosis?

Two of the standard FDA-approved medications for MS (Avonex® and Betaseron®) have been shown to slow a worsening in cognition in MS compared with placebo. One medication used in MS treatment improved measures of cognitive compared with placebo (natalizumab). In addition, a medication used for Alzheimer’s disease, donepezil, has been shown to measurably improve cognition in MS. Other medications are presently under study for this problem.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy