How is acanthosis nigricans diagnosed?

The condition can be diagnosed by a doctor through a medical history and physical examination. Blood work might be done to investigate the cause of acanthosis nigricans. Occasionally, a skin biopsy is performed to get a detailed look at the tissue in a laboratory if the diagnosis is not straightforward on physical examination.

Last reviewed by a Cleveland Clinic medical professional on 03/02/2015.


  • Cleveland Clinic Journal of Medicine
  • Acanthosis Nigricans: Clinical Dermatology

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