How is Peyronie’s disease diagnosed?

The doctor will ask the patient about anything that may have happened before the symptoms appeared, such as an injury. The doctor will feel the hardened tissue caused by the disease, although sometimes it is necessary to do the examination when the penis is erect.

In some cases, the doctor may perform a biopsy. A biopsy is the removal of cells or tissue for examination. The sample will be sent for testing and will be looked at under a microscope.

Last reviewed by a Cleveland Clinic medical professional on 08/08/2018.


  • The National Institute of Diabetes and Digestive and Kidney Diseases. Peyronie's Disease. Accessed 7/24/2015.
  • National Kidney and Urologic Diseases Information Clearinghouse. Erectile Dysfunction. Accessed 8/8/2018.
  • American Urological Association. What is Peyronie’s Disease? Accessed 8/8/2018.

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