What is the prognosis (outlook) for people with stiff person syndrome?

The prognosis for stiff person syndrome varies depending on a person’s symptoms. The severity of the syndrome and speed of decline varies from person to person.

Over time, walking can become more and more difficult. In addition, a person’s ability to perform daily, routine tasks may also decline over time. Various treatments may be helpful in reducing the symptoms in some patients. The increased risk of falls becomes a growing concern as the disorder worsens. Some people may need to use a cane, walker or wheelchair for assistance.

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