Rheumatoid Arthritis

Infusion Reactions in Patients With Rheumatic Diseases Treated in a Rheumatology Infusion Center (2016-2020)

Infusion Reactions in Patients With Rheumatic Diseases Treated in a Rheumatology Infusion Center (N=16593)

2015-2019

The Rheumatology Infusion Center administered 3034 infusions in 2015, 3033 infusions in 2016, 3301 infusions in 2017, 3544 infusions in 2018, and 3681 in 2019. Both biologic and nonbiologic medications were used to treat a large number of patients with rheumatic diseases. Infusion reactions can be serious complications and require established protocols to guarantee appropriate premedication, infusion rates, and treatment for drug reactions to ensure patient safety. In 2015, reactions occurred in 36 of 3034 infusions (1.2%), and were mild in 1, moderate in 29, and severe in 6 infusions. In 2016, reactions occurred in 48 of 3033 infusions (1.6%), and were mild in 1, moderate in 45, and severe in 2 infusions. In 2017, reactions occurred in 80 of 3301 patients (2.4%), and were mild in 4, moderate in 75, and severe in 1 infusions. In 2018, reactions occurred in 51 of the 3544 patients (1.4%), and were mild in 4, moderate in 47, and severe in zero infusions. In 2019, reactions occurred in 79 of the 3681 patients (2.1%), and were mild in 4, moderate in 74, and severe in 1 infusions. Only 15 patients were not able to complete the infusions (0.09%) in 2015-2019.