Neurological Institute Outcomes
Immunotherapy for Neuromuscular Disorders and Infection Risk
Infection Rate Following Immunotherapy for Neuromuscular Disorders
2015 – 2020
Immunotherapy is the most effective treatment for a number of neuromuscular disorders, including inflammatory myopathy, myasthenia gravis, Lambert-Eaton myasthenic syndrome, and chronic inflammatory demyelinating polyneuropathy. Commonly used treatments may include corticosteroids, azathioprine, mycophenolate mofetil, methotrexate, cyclosporine, rituximab, intravenous immunoglobulin, and plasmapheresis. While effective, these treatments can weaken the immune system, leading to complications of infection. At times, resulting infections are severe, requiring hospitalization. Balancing the efficacy of treatment and the risk of infection is often the key in the successful treatment of immune-mediated neuromuscular disorders.