Epilepsy

Pediatric Epilepsy: Seizure Severity

Seizure Severity in Medically Treated Pediatric Epilepsy Patients (N = 2021)

2009 – 2018

The effect of medical treatment on seizure severity was assessed using the Liverpool Seizure Severity Scale (LSSS), a validated patient-completed questionnaire developed to quantify seizure severity. Of the 2021 patients seen from 2009 through 2018, 44.9% improved, 39.6% remained stable, and 15.4% had a worsening in seizure severity. Clinically meaningful change was defined as a total point change of ≥ 5.

Seizure Severity in Surgically Treated Pediatric Epilepsy Patients (N = 238)

2009 – 2018

The effect of surgical treatment on seizure severity was assessed using the LSSS. Of the 238 patients seen from 2009 through 2018, 77.7% improved, 9.2% remained stable, and 13% had a worsening in seizure severity. Clinically meaningful change was defined as a total point change of ≥ 5.

References
  1. Scott-Lennox J, Bryant-Comstock L, Lennox R, Baker GA. Reliability, validity and responsiveness of a revised scoring system for the Liverpool Seizure Severity Scale. Epilepsy Res. 2001 Apr;44(1):53-63.